5 Weeks in testosterone replacement therapy (TRT) Blood Results

[coldbeerz81]

5 Weeks in TRT Blood Results

Hi guys,
5 weeks into my testosterone replacement therapy (TRT) program and I just got my bloods.
Total test 1197 ng/dl (292-1052)
Free test 29.4 ng/dl (4.8-25.0)
SHBG 35.0 nmol/l
Estradiol 21.1 pg/ml (0.0-56.0)

I'm on 200 mg test per week, 1000 Iu of Human Chorionic Gonadotropin (HCG), and 1 mg of Arimidex, all split into 2 doses per week (Saturday and Wednesday). I feel great! Sex drive is way up, gains in the gym are crazy good, and my energy level is amazing. Just wondering what you guys think about the bloods. I think I might be where I need to be.

 

[Megatron28]

When was the blood drawn relative to your last Test injection? And was the Estradiol test sensitive or regular? Your Estradiol may be too low.

 

[coldbeerz81]

Bloods were drawn on Friday. I take my injections on Saturday and Wednesday. Not sure if the estrogen was sensitive or regular. My primary care doc did the test.

 

[Megatron28]

I think you look pretty good, but I would back down on the Aromatase inhibitor (AI). Low E isn't good for you. Best part is that you are feeling great! Hopefully like a new man.

 

[coldbeerz81]

Yeah buddy! Feeling pretty good I must say. I was trying to stay on a half of a mg of Arimidex, but my nipples got sore around the end of week 3.

 

[Megatron28]

Try .25 three times a week perhaps.

 

[tiredguy]

Hi guys,
5 weeks into my testosterone replacement therapy (TRT) program and I just got my bloods.
Total test 1197 ng/dl (292-1052)
Free test 29.4 ng/dl (4.8-25.0)
SHBG 35.0 nmol/l
Estradiol 21.1 pg/ml (0.0-56.0)

I'm on 200 mg test per week, 1000 Iu of Human Chorionic Gonadotropin (HCG), and 1 mg of Arimidex, all split into 2 doses per week (Saturday and Wednesday). I feel great! Sex drive is way up, gains in the gym are crazy good, and my energy level is amazing. Just wondering what you guys think about the bloods. I think I might be where I need to be.

you do the Human Chorionic Gonadotropin (HCG) and the test same day?

 

[coldbeerz81]

Yep. I dose everything on Saturday and Wednesday. Seems to be working alright so far.

 

[halfwit]

Wow, talk about nice dialing in of the hormones! I agree with Megatron, keep an eye on that E2 - you're not terribly low yet, but it's a lot harder to bring it back up than to drop it down. A pretty good indicator of going too low on the estradiol is when your morning wood stops happening. Man, it's so nice to see such great levels.

 

[ws2006]

Great job bro - glad you are seeeing the up side of everything! Made me wonder why I did not start sooner when things turned around for me! I have had to do a little adjusting but not too much and finally feel like I am about right where I want to be.

 

[Daniel_IMT_Staff]

Keep up the good work. Sweet spot for e2 is said to be 24ish, everybody is different. It's a learning period for everybody to get dialed in, looks like you are doing pretty damn good so far.

 

[Megatron28]

Keep up the good work. Sweet spot for e2 is said to be 24ish, everybody is different. It's a learning period for everybody to get dialed in, looks like you are doing pretty damn good so far.

Daniel, I have heard some people suggest that the ratio of Total Test to E2 is important. More so than just the E2 number in a vacuum. Do you have any thoughts on that?

 

[Daniel_IMT_Staff]

Yes, I just posted a Estrogen article I was working on before, the second part of the article will be explaining some of that. Here is a short excerpt:

Libido or sexual desire in men is controlled heavily between a testosterone to estrogen ratio. When your estrogen levels become too high then the resulting ratio of testosterone to estrogen will be lower than desired. Medically, it has been determined that an approximate to this ratio should be 250:1 (tT:e2)

*citation for the ratio missing at the moment, have to look through and see where I got it. It's nothing you should follow either way IMO!

Estrogen is very important and in relation to testosterone it will produce certain effects, personally I see them having a ying-yang relationship. BUT and this is a very big BUT, what does that matter if you establish a relationship in regards to two hormones when they have expressions which vary greatly from individual to individual. Mainly your question is in regards to libido and libido itself is a mystery all together. Rather than looking at a person's labs and trying to make deductions based from numbers; it is more accurate to simply ask "how are you feeling?" rather then measuring serum levels. The main physical effects you want to avoid from estrogen is bloat and gynecomastia, estrogen plays an important part in lipid management among sebaceous gland secretion and actually is seen to improve acne if levels of estrogen is too low. Other than that, the mental effects from estrogen can be horrible on mood swings and emotions, the interaction between neurotransmitters and other hormones of the nuclear family is important as well but testosterone will also exhibit effects on neurotransmitters such as dopamine. It's honestly all too complicated taking in account to all the effects they place and the chain of action they express.

To answer your question, is the tT:e2 ratio important? Yes, and to how it applies in testosterone replacement therapy (TRT), keep an eye on it so it doesn't go below or above range too much but subjective information from the patient is going to tell you more.

 

[Megatron28]

Thanks!

 

[coldbeerz81]

Very informative Daniel. Really appreciate everyone's input! Definitely gonna keep a check on that e2. Probably get more blood work done in a few more weeks.

 

[jomamma007]

Yes, I just posted a Estrogen article I was working on before, the second part of the article will be explaining some of that. Here is a short excerpt:


*citation for the ratio missing at the moment, have to look through and see where I got it. It's nothing you should follow either way IMO!

Estrogen is very important and in relation to testosterone it will produce certain effects, personally I see them having a ying-yang relationship. BUT and this is a very big BUT, what does that matter if you establish a relationship in regards to two hormones when they have expressions which vary greatly from individual to individual. Mainly your question is in regards to libido and libido itself is a mystery all together. Rather than looking at a person's labs and trying to make deductions based from numbers; it is more accurate to simply ask "how are you feeling?" rather then measuring serum levels. The main physical effects you want to avoid from estrogen is bloat and gynecomastia, estrogen plays an important part in lipid management among sebaceous gland secretion and actually is seen to improve acne if levels of estrogen is too low. Other than that, the mental effects from estrogen can be horrible on mood swings and emotions, the interaction between neurotransmitters and other hormones of the nuclear family is important as well but testosterone will also exhibit effects on neurotransmitters such as dopamine. It's honestly all too complicated taking in account to all the effects they place and the chain of action they express.

To answer your question, is the tT:e2 ratio important? Yes, and to how it applies in testosterone replacement therapy (TRT), keep an eye on it so it doesn't go below or above range too much but subjective information from the patient is going to tell you more.

250:1 TT:e2.. Am I missing something. So 1000 test level with 4 estrogen? Unless it's a typo 25:1?

 

[Schweddy]

I bet you can dial down your T injection and cut out the AI.