Ace-031 interest.. Has anyone experimented with this?

[Bjjguy91]

Has anyone ran ace-031 and if so how were the results? What dose? Very interested to learn more about this stuff

 

[JimiThing]

I havent used it but I too am interested.
Myostatin inhibitors def intrigue me and Id love to hear from anyone with some experience with ACE as well.

 

[3J]

so this ace is a myo inhibitor?? is it a peptide?? oral?

i have yet to see a legit myo inhibitor backed by scientific data

 

[JimiThing]

so this ace is a myo inhibitor?? is it a peptide?? oral?

i have yet to see a legit myo inhibitor backed by scientific data

Its an injectable peptide.
I agree, I too havent seen that in humans with the exception of yk-11, which is proven to inhibit myostatin in humans. Thats why Id be interested in hearing more about ACE if anyone can chime in...

 

[3J]

<- frantically looking up yk-11 lol

 

[JimiThing]

<- frantically looking up yk-11 lol

lol, even that, while it is proven to work as a myo inhib in humans there is so little on WHAT that actually translates into as far as effects you know?

 

[3J]

yea there are no human studies out there...

looks like we will have to wait a few years before we have a clear understanding..

interesting that a partial ARM could have full androgen effects.. again, not verified..

but the fact that it states its a much more potent myo inhibitor than dht makes me happy inside lol..

 

[cybrsage]

ACE-031 was discontinued because ALL test subjects started having unaccountable nose bleeds...the nose bleeds stopped when they stopped taking the ACE-031 (and it cleared their system). I would stay away from it. YK-11 is another myostatin inhibitor. Its only side effect (as reported by the body building community - the medical community says they have found none yet) is a weakening of the tendons and other connective tissues. I would recommend using it with something that strengthens them.

Here is my write up on YK-11

http://www.steroidology.com/forum/a...650-yk11-log-sourced-through-sarmssearch.html

I started using it, but that was at the same time I started to have the symptoms that lead to my neck surgery. The two are not related in any way, it was discovered I had two bone spurs on my C7 vertebrae that were literally touching my spinal cord. I will eventually start back up on the YK11, but not for some time (want to fully heal first).

 

[cybrsage]

Here is an article about it. They were testing it for people with Muscular Dystrophy.

Below is the original Quest story titled ACE-031 Clinical Trials in Duchenne MD Stopped for Now, which was published May 3, 2011.

Biopharmaceutical companies Acceleron Pharma and Shire announced April 21, 2011, that MDA-supported clinical trials of ACE-031 for Duchenne muscular dystrophy (DMD) have been halted.

A phase 2, dose-escalation study of ACE-031 in boys with DMD has been terminated, and the extension study for boys who have completed the original study has been suspended, based on preliminary safety data.

Both studies were being conducted in Canada, and the plan was to open study sites in the United States some time in the future.

The adverse events that the trial participants experienced ***8212; minor nose and gum bleeding and dilation of blood vessels in the skin ***8212; were not, in and of themselves, considered dangerous. However, the companies and regulatory agencies involved say they need to fully understand these events before continuing clinical studies of ACE-031.

UPDATE: ACE-031 Clinical Trials in Duchenne MD | Quest Magazine Online