Aminos during intensive training

Blondie_Bombshell

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Its rats, but its interesting.

A biological obstacle in the way of performance during training is the accumulation of ammonia in the blood. We experience this as fatigue. Under normal conditions ammonia is the waste product from protein metabolism, but during an intensive training session the main source of ammonia is the increased production of the energy molecule ATP in the muscle.

In all these processes the body first converts amino acids into their keto-analogues. And in this process the amino group separates from the amino acid in the form of ammonia. The body can also do the opposite, attaching amino groups to keto-amino acids. Thats why doctors use keto-amino acids as a medicine to treat chronic kidney disease. In patients suffering from kidney disease the amount of ammonia in the blood increases dramatically, but the keto-amino acids in a medicine like Ketosteril [see above] lower the concentration.

So could this also work in athletes? Or people who do sports that involve high intensity training? This is what the Brazilians wanted to know.


They tested the idea out on young male rats, of which half had learned to do a kind of strength training on a machine. [Ex] On the day of the experiment, the fitness rats had to do a total of 50 reps at 75 percent of the weight at which they could just manage 1 rep. The remaining half of the lab animals did nothing.

Half of the fitness rats and half of the inactive rats were given 0.1 g Ketosteril orally one hour before the training session started. [KAAA] Thats equivalent to 0.3 g/kg bodyweight

 
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