hes only using 300 mg of deca if hes that senistive to progesterone / prolactin he should never use deca or tren again .and at 500 mg of test WITH 12.5 mg of aromasin i doubt its estrogen but its possible . upping the aromasin to 25 should be fine. letro just drives estrogen into the ground , the goal of antiestrogen meds is to CONTROL estrogen not DESTROY it.
I totally agree, its most likely paranoia, most of the time on the boards it is.
I think your right about pgr as well cause ive went all the way to 800 deca and still not had problems.
there is a big misconception about letro though, I think the reason is because the studies on women show that it wipes out estrogen up to 99%.
letro is strong and its not always necessary, but most of the time it will not wipe out estrogen.
in studies on men it only reduced estrogen like 65%. im not very sensitive to estrogen and ive use it as much as 1.25mg EOD without any issues.
When we take a look at its effects in men, Letrozole actually reduced estrogen in one test subject to undetectable levels (2). In another clinical study, intravenous administration of Letrozole (2.5mcg for 28 days),
Letrozole lowered Estrogen by 46% in the young men tested, and 62% in the elderly subjects. In addition, Letrozole also significantly increased LH levels to a whopping 339 and 323% in the young and the elderly, respectively and Testosterone by 146 and 99%, respectively. (3) Letrozole was also able to produce a peak LH response to Gonadatropin Releasing Hormone equal to a 152 and 52% increase from baseline in either young or older men, respectively.
As you can see, Letrozole is a very powerful drug, and as a result, only very tiny doses are necessary. An effective daily dose of Letrozole for most people is usually about .25-.5mg/day, even though clinically, it is typically used at 2.5mgs/day. Twenty micrograms of Letro was enough, in one study done on men, to reduce estrogen levels by almost a third. (4)
Letrozole normalizes serum testosterone ... [Diabetes Obes Metab. 2005] - PubMed - NCBI
i know 20mcg is a very small dose, but these are men not taking testostoerone.
1 subject did get his estro almost wiped out, so really it just depends on the individual.
what makes one Aromatase inhibitor (AI) stronger than another is the ability to reach dense lipid cells, so really it depends on where the majority of the aroma is happening. this is why some people swear that letro is the only thing that works for them.
taking a 1/4 of a pill of letro E3D is about the same dose they used in the study. so for those who use letro I would say start with that and work up if need be.
