I agree its totally trial and error. Its also wise to get this figured out right away so you always have something to fall back on when you decide to experiment.
if someone is taking 3mg of adex a week there is a problem. it would be silly not to switch to letro even if its just for the cost factor.
the human body is suppose to aromatase roughly .3% if its way out of control its telling you something.
If i had to take that much i would have to question my dose of T, i would most likely reduce since im wasting it converting to E. and figure out if its my thyroid or what the hell is making it do that. While I have no problem taking a marginal dose of testosterone, even though it can effect my cholesterol. im not willing to take the risk of what 3mg of adex will do to my lipids.
"In several small studies, anastrozole showed no marked effects on lipid profile (Dewar et al, 2000; Kataja et al, 2002; Sawada and Sato, 2003; Wojtacki et al, 2004). Kataja et al, (2002) showed LDL levels fell with both exemestane and anastrozole and triglycerides fell with exemestane, but remained stable with anastrozole. However, anastrozole was associated with a higher incidence of hypercholesterolaemia than tamoxifen in the ATAC study (ATAC Trialists Group, 2002). In the Italian Tamoxifen Arimidex (ITA) trial, patients switching to anastrozole after 2 or more years of tamoxifen were also found to have higher levels of hypercholesterolaemia than those continuing on tamoxifen, 8.1 and 2.7%, respectively (Boccardo et al, 2003). In addition, a recent study of the effect of anastrozole on serum lipid profiles in 38 postmenopausal patients with breast cancer
found significant increases in total cholesterol, LDL and HDL cholesterol, apolipoprotein A1, B and lp(a) (Hozumi et al, 2004). Anastrozole was associated with a slightly higher incidence of ischaemic cardiovascular disease than tamoxifen in the ATAC study, but this was not significant (ATAC Trialists Group, 2002)."
http://www.nature.com/bjc/journal/v93/n1s/full/6602692a.html
