Dr. finally proscribed 1mg Arimidex per week....now what?

[ajgnaples]

So my Etradiol went from 70 to 106. My Doc gave me a script for 1mg of Arimidex per week and told me I no longer need to take DIM. He says if Estrogen doesn't go down then he would recommend 2 X 1mg of Arimidex a week until I have lost more weight. I am about 25% BMI, 48 years old with Testosterone Pellets.

He said some patients lose water weight because Estrogen retains water in the body but no other side effects unless I took too much Arimidex. Does it make sense to do just one 1mg per week or should I break the tabs up to .50 X twice a week?

Any input appreciated.

 

[tx045]

I'd break your arimidex down to twice a week but its really going to be a matter of getting dialed in what works for you. Some are really sensitive to ai's, including me.

Either your doc doesnt know jack shit or he's lying to you if he thinks that is the only side caused by high e2.

How do you feel? Your e2 is high and out of range but I think people get caught up in numbers too much

 

[Milton]

would it be possible to get some blood results?

 

[juced_porkchop]

would it be possible to get some blood results?

^^ This......

also i would split the AI dose into 2-4

 

[ajgnaples]

My blood work. I am also starting slowing on Nature Throid to deal with elevated TSH.... 1/4 grain. I will ramp up from there.

Test Name Result Flag Reference Range Lab
FASTING:YES
LIPID PANEL
CHOLESTEROL, TOTAL 138 125-200 mg/dL 01
HDL CHOLESTEROL 42 > OR = 40 mg/dL 01
TRIGLYCERIDES 83 <150 mg/dL 01
LDL-CHOLESTEROL 79 <130 mg/dL (calc) 01

Desirable range <100 mg/dL for patients with CHD or
diabetes and <70 mg/dL for diabetic patients with
known heart disease.

CHOL/HDLC RATIO 3.3 < OR = 5.0 (calc) 01
NON HDL CHOLESTEROL 96 mg/dL (calc) 01
Target for non-HDL cholesterol is 30 mg/dL higher than
LDL cholesterol target.
TSH
TSH 3.10 0.40-4.50 mIU/L 01
ESTRADIOL, ULTRASENSITIVE LC/MS/MS
ESTRADIOL, ULTRASENSITIVE LC/MS/MS 106 HIGH < OR = 29 pg/mL 02

This test was developed and its analytical performance
characteristics have been determined by Quest Diagnostics
Nichols Institute San Juan Capistrano. It has not been
cleared or approved by FDA. This assay has been validated
pursuant to the CLIA regulations and is used for clinical
purposes.
IGF 1, LC/MS
IGF 1, LC/MS 144 52-328 ng/mL 02
Z SCORE (MALE) 0.0 -2.0 - +2.0 SD 02

This test was developed and its analytical performance
characteristics have been determined by Quest Diagnostics
Nichols Institute San Juan Capistrano. It has not been
cleared or approved by FDA. This assay has been validated
pursuant to the CLIA regulations and is used for clinical
purposes.

Z SCORE (FEMALE) DNR 02
CBC (INCLUDES DIFF/PLT)
WHITE BLOOD CELL COUNT 4.2 3.8-10.8 Thousand/uL 01
RED BLOOD CELL COUNT 4.69 4.20-5.80 Million/uL 01
HEMOGLOBIN 15.3 13.2-17.1 g/dL 01
HEMATOCRIT 46.1 38.5-50.0 % 01
MCV 98.3 80.0-100.0 fL 01
MCH 32.6 27.0-33.0 pg 01
MCHC 33.2 32.0-36.0 g/dL 01
RDW 13.7 11.0-15.0 % 01
PLATELET COUNT 172 140-400 Thousand/uL 01
MPV 9.5 7.5-11.5 fL 01
ABSOLUTE NEUTROPHILS 2146 1500-7800 cells/uL 01
ABSOLUTE BAND NEUTROPHILS DNR 0-750 cells/uL 01
1 of 2
ABSOLUTE METAMYELOCYTES DNR 0 cells/uL 01
ABSOLUTE MYELOCYTES DNR 0 cells/uL 01
ABSOLUTE PROMYELOCYTES DNR 0 cells/uL 01
ABSOLUTE LYMPHOCYTES 1558 850-3900 cells/uL 01
ABSOLUTE MONOCYTES 307 200-950 cells/uL 01
ABSOLUTE EOSINOPHILS 176 15-500 cells/uL 01
ABSOLUTE BASOPHILS 13 0-200 cells/uL 01
ABSOLUTE BLASTS DNR 0 cells/uL 01
ABSOLUTE NUCLEATED RBC DNR 0 cells/uL 01
NEUTROPHILS 51.1 % 01
BAND NEUTROPHILS DNR % 01
METAMYELOCYTES DNR % 01
MYELOCYTES DNR % 01
PROMYELOCYTES DNR % 01
LYMPHOCYTES 37.1 % 01
REACTIVE LYMPHOCYTES DNR 0-10 % 01
MONOCYTES 7.3 % 01
EOSINOPHILS 4.2 % 01
BASOPHILS 0.3 % 01
BLASTS DNR % 01
NUCLEATED RBC DNR 0 /100 WBC 01
COMMENT(S) DNR 01
DHEA SULFATE
DHEA SULFATE 194 70-495 mcg/dL 01

DHEA-S values fall with advancing age.
For reference, the reference intervals for 31-40 year
old patients are:

Male: 106-464 mcg/dL
Female: 23-266 mcg/dL

PSA, TOTAL
PSA, TOTAL 0.9 < OR = 4.0 ng/mL 01

This test was performed using the Siemens
chemiluminescent method. Values obtained from
different assay methods cannot be used
interchangeably. PSA levels, regardless of
value, should not be interpreted as absolute
evidence of the presence or absence of disease.

TESTOSTERONE,FR(DIALYSIS) AND TOTAL(LC/MS/MS)
TESTOSTERONE, TOTAL, LC/MS/MS 2265 HIGH 250-1100 ng/dL 03

For more information on this test, go to
education.questdiagnostics.com/faq/
TotalTestosteroneLCMSMS

FREE TESTOSTERONE 434.9 HIGH 35.0-155.0 pg/mL 03

 

[ajgnaples]

I'd break your arimidex down to twice a week but its really going to be a matter of getting dialed in what works for you. Some are really sensitive to ai's, including me.

Either your doc doesnt know jack shit or he's lying to you if he thinks that is the only side caused by high e2.

How do you feel? Your e2 is high and out of range but I think people get caught up in numbers too much

LOL! No I have sensitive nipples after running, I am a bit emotional too (weepy), my libido is not great, too. My muscle building isn't great but I am focusing on losing weight but I suspect with Estradiol above 100, it sounds like accomplishing this is a bit up hill.

 

[Dreaded Pirate Roberts]

I'd break your arimidex down to twice a week but its really going to be a matter of getting dialed in what works for you. Some are really sensitive to ai's, including me.

Either your doc doesnt know jack shit or he's lying to you if he thinks that is the only side caused by high e2.

How do you feel? Your e2 is high and out of range but I think people get caught up in numbers too much

I agree split the pill and take twice a week.

 

[ajgnaples]

Follow-up

I agree split the pill and take twice a week.

Yea I might start at an 1/8 of am mg or .25mg every 3 days to begin with. I guess some people can be very sensitive to AI and totally shutdown production of E.... I tend to be sensitive to medicine. I am taking blood every two weeks so I will slowly ramp up.

I just started also taking 1/4 Grain of Nature Throid to increase my thyroid gland.....

 

[Megatron28]

Your problem is that your TT is at 2265ng/dl. You are not on TRT. You are running a cycle. That is way too high for TRT. Lower your test dose and your E2 will drop.

How much test does your doc have you on?

 

[ajgnaples]

Your problem is that your TT is at 2265ng/dl. You are not on TRT. You are running a cycle. That is way too high for TRT. Lower your test dose and your E2 will drop.

How much test does your doc have you on?

Good question. I am on 10 pellets or roughly 2000mg. I believe it is Testopel. The Test comes into the bloodstream based on being drawn down subcutaneously after work outs. Supposed to last as long as 6 months. Since the pellets are in subcutaneously they are in for the long-term and I can't take them out.

 

[Megatron28]

Good question. I am on 10 pellets or roughly 2000mg. I believe it is Testopel. The Test comes into the bloodstream based on being drawn down subcutaneously after work outs. Supposed to last as long as 6 months. Since the pellets are in subcutaneously they are in for the long-term and I can't take them out.

Pellets suck. You should switch to injections. And get your doc to put you on a TRT dose -- not a cycle.

 

[ajgnaples]

Pellets suck. You should switch to injections. And get your doc to put you on a TRT dose -- not a cycle.

What is the difference Megatron? I appreciate your understanding a lot.

 

[IMT staff]

Way too high

 

[Megatron28]

What is the difference Megatron? I appreciate your understanding a lot.

Pellets involve cutting you open and surgically implanting them. There is increased risk with surgery. And the cost is much more -- but I am sure you doc doesn't mind billing it out as a surgical procedure for the rest of your life.

With injections, it would be really easy to adjust your dosage. You are unfortunately locked in for quite some time now at an unhealthy supraphysiological dose of testosterone right now until the pellets wear off. Injections is much cheaper. They can be done at home by you. You don't have to see your doctor as often as he can just call in a refill for you to the pharmacy. No surgical risk.

I just can't see why anyone would go down the pellets route. I don't see one advantage to doing it that way for the patient. If you are a farmer and you want to get some better yield out of your cows, pellets clearly are the way to go. But you aren't a cow.

 

[Milton]

did you make the switch to injections?

 

[ajgnaples]

I have 3 or more months still to go on Pellets. I will say its very convenient but the loss of control is what I don't like.