E2 control for TRT...............

[Alpin]

Noticed my recent labs have Estradiol(regular panel) result of 134 pmol/l (36 pg/ml) 2 days before my last ADEX dose which was 0.25 mg, I took 0.25 mg ADEX again before that 2 days earlier.
The reason for the second dosing 2 days before the last blood labs was noticing lump in pec....
I know this means elevated E2....at least for me. Cause I had it before in the past.
I'm running 1000 i.u./week of HCG and 140 mg T split in 2 shots....
I'm not noticing that much higher libido in general even though my TT is 1268 ng/dl....
I'm thinking my E2 is not dialed in yet...
Just feel a little tired, low libido, erections,
What do you guys think ?
def. E4D dosing of ADEX doesn't look like it's gonna cut it. I'm also prone to anxiety if I lower my E2 level too much i.e. below 75 pmol/l which is 20 pg/ml

 

[HammerT1]

Have you thought about trying Stane instead of the adex? Stane works better for me then the adex and my lipids are much happier too. Maybe that much hcg spiking the estrogen too. I normally only run 250iux2 but more does feel better.
It sucks when things get out of whack and trying to dial them back in.

 

[STAUNCHED427]

def. E4D dosing of ADEX doesn't look like it's gonna cut it. I'm also prone to anxiety if I lower my E2 level too much i.e. below 75 pmol/l which is 20 pg/ml

E4D dosing of adex is a little wide, I'd go E3D at most, in fact try that and see how you go it seems the more logical option. I remember you saying E4D dosing was your choice not your doctors... may I ask why you choose E4D over at least E3D considering it may be the right dose to lower your e2 into a bit more appropriate level?

Maybe go 250IU split twice a week with the hCG or drop the T dose a little to bring your TT level closer to 1000ng/dl which could help the e2 itself.

 

[Alpin]

E4D dosing of adex is a little wide, I'd go E3D at most, in fact try that and see how you go it seems the more logical option. I remember you saying E4D dosing was your choice not your doctors... may I ask why you choose E4D over at least E3D considering it may be the right dose to lower your e2 into a bit more appropriate level?

Maybe go 250IU split twice a week with the hCG or drop the T dose a little to bring your TT level closer to 1000ng/dl which could help the e2 itself.

Might try that (lower T dose...) don't think I need to cruise at 1270 ng/dl ....lol
When fist hoping on TRT I would dose ADEX EOD at this dose....
I got vicious anxiety!!!!
I mean vicious...would sit down to eat without finishing the meal and my heart would beat faster and would have endless nervous energy that only 2-3 hours of training could bring down.
Backed off the ADEX for a week and felt better. Splitted up the shots and felt all this anxiety subside so I went to E4D dosing of the ADEX....
My PSA needs help too....
1.59 ug/l and I'm thinking my E2 is cruising at 40-55 pg/ml on this protocol....
and I'll tell you why....
took an extra ADEX dose(cause I felt a gyno lump starting to develop) 48 hours before my bloodwork and E2 came back as 36 pg/ml on this test. This tells me I was a bit higher the days before.

 

[STAUNCHED427]

Me personally I'm happy being at 1200ng/dl on TRT at my age and it isn't overly high but I choose to do so for the extra libido, sense of well-being, body comp basically all the goodies just a little more amplified without going drastic.

Just goes to show how one persons body will react differently to others, .25mg EOD for you dumps your e2 quite well, whereas for me 1mg ED does jack shit!

The half life of adex with E4D dosing would create a bit of an up and down rollercoaster I'd say aswell.

Is PSA possibly a result of e2 being a little on the high side maybe? It could also be the high test or a combo...

 

[Alpin]

I'm 1268 ng/dl two days from 70 mg pin....
I pin 70 mg T E3D.
I wouldn't mind 1100 ng/dl.....
that ain't bad either....
I doubt my levels fall much though before shot on 3rd day...
I don't want to go in again and get "trough" level on paper if i'm cruising at 1200+ before next shot.
I don't want that shit on paper....

 

[jomamma007]

I'm 1268 ng/dl two days from 70 mg pin....
I pin 70 mg T E3D.
I wouldn't mind 1100 ng/dl.....
that ain't bad either....
I doubt my levels fall much though before shot on 3rd day...
I don't want to go in again and get "trough" level on paper if i'm cruising at 1200+ before next shot.
I don't want that shit on paper....

Lower your test dose to 60mgs E3D and lower hcg to 250iu 2-3 times a week.
Buy some aromasin and take it daily or EoD to keep things more consistent.
1268 is your trough if it's right before your next pin. Do you mean peak?

 

[Spunkey71]

Apollon always does Peak testing (according to his multiple posts) so 1268 really isn't all that high for a peak, I would guess his trough is somewhere around 900-1000.

 

[Alpin]

Lower your test dose to 60mgs E3D and lower hcg to 250iu 2-3 times a week.
Buy some aromasin and take it daily or EoD to keep things more consistent.
1268 is your trough if it's right before your next pin. Do you mean peak?

I don't know....
I took labs 2 days from pin....
I pin E3D's so I imagine the drop is not much by the next day....

 

[jomamma007]

I don't know....
I took labs 2 days from pin....
I pin E3D's so I imagine the drop is not much by the next day....

yeah so you have a trough of 1268 which is pretty dam high,

 

[STAUNCHED427]

I'd aim for a trough no lower than 900, pref 1000 so at the peak you'll be somewhere around 1200 and will keep you (hopefully) in check with e2 side of things.

 

[Alpin]

yeah so you have a trough of 1268 which is pretty dam high,

feels normal to me....
and I've suffered with anxiety for years.....
goes to show u.

 

[STAUNCHED427]

feels normal to me....
and I've suffered with anxiety for years.....
goes to show u.

Well if you feel great at 1200ng/dl maybe look at lowering the hCG dose and try the adex E3D, let us know how it goes.

 

[Soybean70]

I love stane. 5mg at bedtime. If i dont take it, my sex drive and energy drops

 

[Alpin]

I love stane. 5mg at bedtime. If i dont take it, my sex drive and energy drops

Stane ?

 

[Alpin]

Well if you feel great at 1200ng/dl maybe look at lowering the hCG dose and try the adex E3D, let us know how it goes.

Not lowering nothing...
bwahahhaha. Taking ADEX E3D now.

 

[Alpin]

I'd aim for a trough no lower than 900, pref 1000 so at the peak you'll be somewhere around 1200 and will keep you (hopefully) in check with e2 side of things.

I noticed there's not much diff between "peak" and "trough" when shooting T E3D.
It's basically one constant level with little variance.

 

[Soybean70]

Liquid stane=aromasin (exemestane)

 

[Alpin]

Liquid stane=aromasin (exemestane)

is it FDA approved for men ?
I'm not too familiar with it

 

[STAUNCHED427]

Not lowering nothing...
bwahahhaha. Taking ADEX E3D now.

Haha fair enough I agree to be honest, I like having my T levels around 1500ng/dl, when Im older and retire from bodybuilding I lower them to a more appropriate 1000ng/dl.

I noticed there's not much diff between "peak" and "trough" when shooting T E3D.
It's basically one constant level with little variance.

Yep that's what you want, I'm on E3.5D it works out to every 82 hours. Much, much better than once a week.

Stane has to be dosed ED, stick with adex if you can. There are benefeits, but you have to weigh up the extra cost/daily dosing if that's not a hassle then go for it. I'm switching back to adex again hopefully it won't bum on me like previously I will be getting a different brand as well, it's easier to dose E2D or E3D, plus stane crushes my e2 pretty damn good.