Exemestane and HPTA?

[808Surfa]

Hey guys, so I'm thinking of *testing* out some RUI stane on my lab rat to clear up or reduce some non gear related gyno. Not that much really, but definitely annoying.

Anyways, I was wondering if anyone's come across anything regarding Exemestane and its effects on the HPTA? I know it's a steroidal Aromatase inhibitor (AI), and that makes me a little worried. My lab rat's never done gear, and at only 21, is not looking to do gear for at least the next decade, if ever...

But he really wants to do something to reduce gyno. I've been researching and it seems like the only effects Stane would have are indirect, from lowering estrogen, thereby triggering greater LH release. But since it is a steroidal compound, I just want to be as near to 100% sure that it DOES NOT have any direct anabolic/androgenic/HPTA modulating abilities, and that it's only actions are to bind up aromatase.

Thanks for the help

 

[THAISEXGIRLS]

Aromasin(exemestane) increases testosterone levels so it must either mimick or increase the production of luteinizing hormone or follicle stimulating hormone in order to do that thus it must effect the hypothalamic pituitary axis. I mean my knowledge is very limited but it is my understanding that in order to raise indigenous testosterone levels the drug must stimulate of mimick LH or FSH so therefore the HTPA must be effected. I am interested to see what some other people at ology think about that.

If gyno is the problem doesn't it make more sense to take a selective estrogen receptor modulator (SERM) such as nolvadex to bind with the estrogen receptors in breast tissue preventing further gynecomastia symptoms?

 

[808Surfa]

Yeah I thought so too until I read this,

Health and fitness articles: Clomid & Nolvadex Toxic Side Effects Exposed

and this

16 Ways to Fight Gynecomastia

what I mean is, does this Steroidal Aromatase inhibitor (AI) have any effects which could trigger the negative feedback loop, thereby reducing production of LH? It seems to me that there's really been nothing done to see whether Exemestane raises testosterone directly or indirectly via LH. That's a little scary because lab rat don't want to take anything that could in any way shutdown or reduce natural test production

 

[Kane_Red_Machine]

if you want to get my point of view, letrozole is better to reduce gyno.