TheJasonSensation
New member
After, reading mixed things on the web about glutamine, I did some research and found a reliable study on glutamine using academic search complete through my school.
Abstract: We examined the effect of a post-exercise oral carbohydrate (CHO, 1 gkg–1h–1) and essential amino acid
(EAA, 9.25 g) solution containing glutamine (0.3 g/kg BW; GLN trial) versus an isoenergetic CHO–EAA solution without
glutamine (control, CON trial) on muscle glycogen resynthesis and whole-body protein turnover following 90 min of cycling
at 65% VO2 peak. Over the course of 3 h of recovery, muscle biopsies were taken to measure glycogen resynthesis
and mixed muscle protein synthesis (MPS), by incorporation of [ring-2H5] phenylalanine. Infusion of [1-13C] leucine was
used to measure whole-body protein turnover. Exercise resulted in a significant decrease in muscle glycogen (p < 0.05)
with similar declines in each trial. Glycogen resynthesis following 3 h of recovery indicated no difference in total accumulation
or rate of repletion. Leucine oxidation increased 2.5 fold (p < 0.05) during exercise, returned to resting levels immediately
post-exercise,and was again elevated at 3 h post-exercise (p < 0.05). Leucine flux, an index of whole-body protein
breakdown rate, was reduced during exercise, but increased to resting levels immediately post-exercise, and was further increased
at 3 h post-exercise (p < 0.05), but only during the CON trial. Exercise resulted in a marked suppression of
whole-body protein synthesis (50% of rest; p < 0.05), which was restored post-exercise; however, the addition of glutamine
did not affect whole-body protein synthesis post-exercise. The rate of MPS was not different between trials. The addition
of glutamine to a CHO + EAA beverage had no effect on post-exercise muscle glycogen resynthesis or muscle
protein synthesis, but may suppress a rise in whole-body proteolysis during the later stages of recovery.
I can't attach the document as it is 6kb too big, but if you can view it here:
web.ebscohost.com.proxy.ohiolink.edu:9099/ehost/pdfviewer/pdfviewer?sid=05c807df-6c05-40cf-8543-7f0a089c7d94%40sessionmgr14&vid=6&hid=17
Abstract: We examined the effect of a post-exercise oral carbohydrate (CHO, 1 gkg–1h–1) and essential amino acid
(EAA, 9.25 g) solution containing glutamine (0.3 g/kg BW; GLN trial) versus an isoenergetic CHO–EAA solution without
glutamine (control, CON trial) on muscle glycogen resynthesis and whole-body protein turnover following 90 min of cycling
at 65% VO2 peak. Over the course of 3 h of recovery, muscle biopsies were taken to measure glycogen resynthesis
and mixed muscle protein synthesis (MPS), by incorporation of [ring-2H5] phenylalanine. Infusion of [1-13C] leucine was
used to measure whole-body protein turnover. Exercise resulted in a significant decrease in muscle glycogen (p < 0.05)
with similar declines in each trial. Glycogen resynthesis following 3 h of recovery indicated no difference in total accumulation
or rate of repletion. Leucine oxidation increased 2.5 fold (p < 0.05) during exercise, returned to resting levels immediately
post-exercise,and was again elevated at 3 h post-exercise (p < 0.05). Leucine flux, an index of whole-body protein
breakdown rate, was reduced during exercise, but increased to resting levels immediately post-exercise, and was further increased
at 3 h post-exercise (p < 0.05), but only during the CON trial. Exercise resulted in a marked suppression of
whole-body protein synthesis (50% of rest; p < 0.05), which was restored post-exercise; however, the addition of glutamine
did not affect whole-body protein synthesis post-exercise. The rate of MPS was not different between trials. The addition
of glutamine to a CHO + EAA beverage had no effect on post-exercise muscle glycogen resynthesis or muscle
protein synthesis, but may suppress a rise in whole-body proteolysis during the later stages of recovery.
I can't attach the document as it is 6kb too big, but if you can view it here:
web.ebscohost.com.proxy.ohiolink.edu:9099/ehost/pdfviewer/pdfviewer?sid=05c807df-6c05-40cf-8543-7f0a089c7d94%40sessionmgr14&vid=6&hid=17
