GW-1516: BURN FAT and GAIN MUSCLE! Find out how!

More on Liquid GW1516

As many are aware GW1516 is one of the most exciting research chemicals currently available. We are proud to now be offering this compound for your research purposes. As always we will try to provide you with as much information possible to ensure the success of your research experiments.

The list of benefits attributed to this compound are quite impressive. It has been successfully used in research to improve such things as obesity, insulin resistance, metabolic syndrome, lipid profile (cholesterol), and cardiovascular disease as well as cardiovascular endurance. The studies referenced at the bottom of this article point out benefit after benefit in all of the above mentioned areas.

As with all research compounds there are direct and indirect side effects. The above mentioned things are all direct effects. GW is a peroxisome proliferator-activated receptor modulator (PRAR Modulator).There are small incidences documented in a very small number of studies with PRAR Modulators with one indirect effect that may be prudent to address. Apparently there is a small increase in the likelihood of research subjects developing stomach polyps. While this is worth being aware of, the good news is in those very same studies it is documented that administration of a COX-2 inhibitor virtually eliminates this increased possibility.

That's great news so what is a COX_2 Inhibitor? It is a type of NSAID, or NON Steroidal Anti Inflammatory Drug. A prescription example of a COX-2 Inhibitor would be the drug Celecoxib. The problem with the administration of a prescription COX-2 Inhibitor is they also contain traditional NSAID effects and should not be frequently administered to research subjects due to a myriad of potential adverse side effects. So what***8217;s so good about that news you may ask? Well there is another readily available, inexpensive COX-2 Inhibitor available OTC as a supplement. Tribulus terrestris is an effective COX-2 inhibitor that does not contain the additional forms of NSAIDS that would expose our research subjects to the previously mentioned potential adverse side effects.

To sum it up based on the information above and in the studies referenced below when researching with Liquid GW1516 the addition of the inexpensive supplement tribulus would probably be a prudent investment. Again we are very excited about offering the exceptional compound Liquid GW1516 for use in your research. We will continue to provide you with all the latest information to make your research as safe and successful as possible!


Refs:
*Activation of nuclear hormone receptor peroxisome proliferator-activated receptor-delta accelerates intestinal adenoma growth. Gupta RA, Wang D, Katkuri S, Wang H, Dey SK, DuBois RN
Department of Medicine, The Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, Tennessee 37232-6838, USA. PMID 14758356
*Berger J, Moller DE (2002). "The mechanisms of action of PPARs". Annu. Rev. Med. 53: 409***8211;35. doi:10.1146/annurev.med.53.082901.104018. PMID 11818483
* Peroxisome proliferator-activated receptors, metabolic syndrome and cardiovascular disease. Salman Azhar Future Cardiol. 2010 September; 6(5): 657***8211;691. doi: 10.2217/fca.10.86 PMCID: PMC3246744 NIHMSID: NIHMS345357
* Evaluation of natural products on inhibition of inducible cyclooxygenase (COX-2) and nitric oxide synthase (iNOS) in cultured mouse macrophage cells. Hong CH, Hur SK, Oh OJ, Kim SS, Nam KA, Lee SK Department of Pharmacy, College of Pharmacy, Ewha Womans University, 11-1 Daehyun-dong, Seodaemun-ku, 120-750, Seoul, South Korea Journal of ethnopharmacology 83:1-2 2002 Nov pg 153-9 PMID 12413723
*Lipid effects of peroxisome proliferator-activated receptor-***948; agonist GW501516 in subjects with low high-density lipoprotein cholesterol: characteristics of metabolic syndrome. Olson EJ, Pearce GL, Jones NP, Sprecher DL. Lipid effects of peroxisome pr... [Arterioscler Thromb Vasc Biol. 2012] - PubMed - NCBI
*Metabolic remodeling agents show beneficial effects in the dystrophin-deficient mdx mouse model.Jahnke VE, Van Der Meulen JH, Johnston HK, Ghimbovschi S, Partridge T, Hoffman EP, Nagaraju K. Metabolic remodeling agents show beneficial ef... [Skelet Muscle. 2012] - PubMed - NCBI
 
Last edited:
More on Liquid GW1516

As many are aware GW1516 is one of the most exciting research chemicals currently available. We are proud to now be offering this compound for your research purposes. As always we will try to provide you with as much information possible to ensure the success of your research experiments.

The list of benefits attributed to this compound are quite impressive. It has been successfully used in research to improve such things as obesity, insulin resistance, metabolic syndrome, lipid profile (cholesterol), and cardiovascular disease as well as cardiovascular endurance. The studies referenced at the bottom of this article point out benefit after benefit in all of the above mentioned areas.

As with all research compounds there are direct and indirect side effects. The above mentioned things are all direct effects. GW is a peroxisome proliferator-activated receptor modulator (PRAR Modulator).There are small incidences documented in a very small number of studies with PRAR Modulators with one indirect effect that may be prudent to address. Apparently there is a small increase in the likelihood of research subjects developing stomach polyps. While this is worth being aware of, the good news is in those very same studies it is documented that administration of a COX-2 inhibitor virtually eliminates this increased possibility.

That’s great news so what is a COX_2 Inhibitor? It is a type of NSAID, or NON Steroidal Anti Inflammatory Drug. A prescription example of a COX-2 Inhibitor would be the drug Celecoxib. The problem with the administration of a prescription COX-2 Inhibitor is they also contain traditional NSAID effects and should not be frequently administered to research subjects due to a myriad of potential adverse side effects. So what’s so good about that news you may ask? Well there is another readily available, inexpensive COX-2 Inhibitor available OTC as a supplement. Tribulus terrestris is an effective COX-2 inhibitor that does not contain the additional forms of NSAIDS that would expose our research subjects to the previously mentioned potential adverse side effects.

To sum it up based on the information above and in the studies referenced below when researching with Liquid GW1516 the addition of the inexpensive supplement tribulus would probably be a prudent investment. Again we are very excited about offering the exceptional compound Liquid GW1516 for use in your research. We will continue to provide you with all the latest information to make your research as safe and successful as possible!


Refs:
*Activation of nuclear hormone receptor peroxisome proliferator-activated receptor-delta accelerates intestinal adenoma growth. Gupta RA, Wang D, Katkuri S, Wang H, Dey SK, DuBois RN
Department of Medicine, The Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, Tennessee 37232-6838, USA. PMID 14758356
*Berger J, Moller DE (2002). "The mechanisms of action of PPARs". Annu. Rev. Med. 53: 409–35. doi:10.1146/annurev.med.53.082901.104018. PMID 11818483
* Peroxisome proliferator-activated receptors, metabolic syndrome and cardiovascular disease. Salman Azhar Future Cardiol. 2010 September; 6(5): 657–691. doi: 10.2217/fca.10.86 PMCID: PMC3246744 NIHMSID: NIHMS345357
* Evaluation of natural products on inhibition of inducible cyclooxygenase (COX-2) and nitric oxide synthase (iNOS) in cultured mouse macrophage cells. Hong CH, Hur SK, Oh OJ, Kim SS, Nam KA, Lee SK Department of Pharmacy, College of Pharmacy, Ewha Womans University, 11-1 Daehyun-dong, Seodaemun-ku, 120-750, Seoul, South Korea Journal of ethnopharmacology 83:1-2 2002 Nov pg 153-9 PMID 12413723
*Lipid effects of peroxisome proliferator-activated receptor-***948; agonist GW501516 in subjects with low high-density lipoprotein cholesterol: characteristics of metabolic syndrome. Olson EJ, Pearce GL, Jones NP, Sprecher DL. Lipid effects of peroxisome pr... [Arterioscler Thromb Vasc Biol. 2012] - PubMed - NCBI
*Metabolic remodeling agents show beneficial effects in the dystrophin-deficient mdx mouse model.Jahnke VE, Van Der Meulen JH, Johnston HK, Ghimbovschi S, Partridge T, Hoffman EP, Nagaraju K. Metabolic remodeling agents show beneficial ef... [Skelet Muscle. 2012] - PubMed - NCBI
 
More on Liquid GW1516

As many are aware GW1516 is one of the most exciting research chemicals currently available. We are proud to now be offering this compound for your research purposes. As always we will try to provide you with as much information possible to ensure the success of your research experiments.

The list of benefits attributed to this compound are quite impressive. It has been successfully used in research to improve such things as obesity, insulin resistance, metabolic syndrome, lipid profile (cholesterol), and cardiovascular disease as well as cardiovascular endurance. The studies referenced at the bottom of this article point out benefit after benefit in all of the above mentioned areas.

As with all research compounds there are direct and indirect side effects. The above mentioned things are all direct effects. GW is a peroxisome proliferator-activated receptor modulator (PRAR Modulator).There are small incidences documented in a very small number of studies with PRAR Modulators with one indirect effect that may be prudent to address. Apparently there is a small increase in the likelihood of research subjects developing stomach polyps. While this is worth being aware of, the good news is in those very same studies it is documented that administration of a COX-2 inhibitor virtually eliminates this increased possibility.

That’s great news so what is a COX_2 Inhibitor? It is a type of NSAID, or NON Steroidal Anti Inflammatory Drug. A prescription example of a COX-2 Inhibitor would be the drug Celecoxib. The problem with the administration of a prescription COX-2 Inhibitor is they also contain traditional NSAID effects and should not be frequently administered to research subjects due to a myriad of potential adverse side effects. So what’s so good about that news you may ask? Well there is another readily available, inexpensive COX-2 Inhibitor available OTC as a supplement. Tribulus terrestris is an effective COX-2 inhibitor that does not contain the additional forms of NSAIDS that would expose our research subjects to the previously mentioned potential adverse side effects.

To sum it up based on the information above and in the studies referenced below when researching with Liquid GW1516 the addition of the inexpensive supplement tribulus would probably be a prudent investment. Again we are very excited about offering the exceptional compound Liquid GW1516 for use in your research. We will continue to provide you with all the latest information to make your research as safe and successful as possible!


Refs:
*Activation of nuclear hormone receptor peroxisome proliferator-activated receptor-delta accelerates intestinal adenoma growth. Gupta RA, Wang D, Katkuri S, Wang H, Dey SK, DuBois RN
Department of Medicine, The Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, Tennessee 37232-6838, USA. PMID 14758356
*Berger J, Moller DE (2002). "The mechanisms of action of PPARs". Annu. Rev. Med. 53: 409–35. doi:10.1146/annurev.med.53.082901.104018. PMID 11818483
* Peroxisome proliferator-activated receptors, metabolic syndrome and cardiovascular disease. Salman Azhar Future Cardiol. 2010 September; 6(5): 657–691. doi: 10.2217/fca.10.86 PMCID: PMC3246744 NIHMSID: NIHMS345357
* Evaluation of natural products on inhibition of inducible cyclooxygenase (COX-2) and nitric oxide synthase (iNOS) in cultured mouse macrophage cells. Hong CH, Hur SK, Oh OJ, Kim SS, Nam KA, Lee SK Department of Pharmacy, College of Pharmacy, Ewha Womans University, 11-1 Daehyun-dong, Seodaemun-ku, 120-750, Seoul, South Korea Journal of ethnopharmacology 83:1-2 2002 Nov pg 153-9 PMID 12413723
*Lipid effects of peroxisome proliferator-activated receptor-***948; agonist GW501516 in subjects with low high-density lipoprotein cholesterol: characteristics of metabolic syndrome. Olson EJ, Pearce GL, Jones NP, Sprecher DL. Lipid effects of peroxisome pr... [Arterioscler Thromb Vasc Biol. 2012] - PubMed - NCBI
*Metabolic remodeling agents show beneficial effects in the dystrophin-deficient mdx mouse model.Jahnke VE, Van Der Meulen JH, Johnston HK, Ghimbovschi S, Partridge T, Hoffman EP, Nagaraju K. Metabolic remodeling agents show beneficial ef... [Skelet Muscle. 2012] - PubMed - NCBI
 
RUI-products said:
What product is that? It's called GW-501516, GW-1516 or GW for short. Over the past months research and feedback into this compound has been booming with positive results and demand has skyrocketed.

Ok so if you don't already know what GW is you may be thinking "what's so special about this compound, spill it already". Well here is a little bit about GW and why I feel it will continue to grow in its research with no slowing down anytime soon.

GW affects the peroxisome proliferator receptor (PPR) in the body and is considered a compound in a class called peroxisome proliferator activated receptor modulators (PPARM's). This is very important because PPAR's effect many biological processes in the body.

GW has a wide variety of effects in the body such as cell energy metabolism, insulin secretion, fatty acid oxidation, and even affects muscle inflammation and damage (in a positive way). In energy metabolism GW was shown to improve mitochondrial morphology in palmitate treated b-cells and this showed to heighten the energy levels in research subjects.

This GW compound is an amazing compound to work with for many reasons, but the main one that is being talked about right now and that researchers are raving about is GW's fat-loss enhancing abilities! GW shows these abilities on many different levels. It will not only higher the test subjects metabolism leading the way to enhanced fat-loss, but will also change the way the body handles fat in the blood and how insulin is released into the body. All these positive findings are what give GW its amazingly powerful fat-loss enhancing qualities. These findings have shown that GW may even be a possible future treatment for various diseases and is currently being looked at for treating diseases such as dyslipidemia and obesity.

GW has also been found to play a role in the development of some diseases like diabetes and obesity amongst many others. To me that means the research of GW may also open doors to possible ways of treating some diseases never thought of before, it really is interesting and promising in this regard.

Aside from its well-known fat-loss enhancing qualities, GW has been shown to have many protective qualities as well. GW has been shown in research to have muscular protective and enhancing effects and this seems to be related to a decrease in muscle inflammation and damage. GW has also showed an increase in the muscular weight of the research subjects that were subjected to these tests.

GW has shown to elicit cardiovascular protection possibly due to its actions in decreasing insulin spikes as found in current research. This leads me to believe that the cardio protective actions found in GW in research subjects with obesity are not only related to the fat-loss enhancing qualities of GW itself but also its positive effects on insulin secretion and also its effects on dyslipidemia. GW shows its positive effects in dyslipidemia by preventing the down-regulation of AMPK that can be caused by high fat or subpar diets. GW does this by amplifying the PGC-1a-Lipin 1-PPAR pathway and this gives rise to increased fatty acid oxidation in the blood. To put it simply it can lower cholesterol levels in most settings of research and of course we know high cholesterol levels can negatively impact heart health.

With GW offering muscular protection and enhancement, along with obviously extreme abilities in enhancing fat-loss, I just don't see GW research slowing down anytime soon and the feedback from researchers has been wonderful. I am happy to now have enough research data on GW-1516 to put this article together for you all, explaining the many known benefits to GW research. I hope that this opens the door to other researchers expanding the already well-established data on GW and finding new possible uses or explanations for its actions. This is an amazing compound and I hope that this article has shed some light onto GW's amazing abilities and that the research continues to grow as it currently is!

Check it out >> Liquid GW1516 30mL 5mg/mL or Liquid GW1516 60mL 5mg/mL

Refs:
1) Lipid effects of GW501516 in subjects.Olson EJ, Pearce GL, Jones NP, Sprecher DL. Lipid effects of peroxisome pr... [Arterioscler Thromb Vasc Biol. 2012] - PubMed - NCBI
2) PPAR in humans: genetic and pharmacological evidence for a significant metabolic functions.Karpe F, Ehrenborg EE. PPARdelta in humans: genetic and pharmacol... [Curr Opin Lipidol. 2009] - PubMed - NCBI
3) Mechanism of action of a peroxisome proliferator-activated receptor agonist on lipoprotein metabolism in dyslipidemic subjects.Ooi EM, Watts GF, Sprecher DL, Chan DC, Barrett PH. Mechanism of action of a peroxisome ... [J Clin Endocrinol Metab. 2011] - PubMed - NCBI
4) Metabolic remodeling agents show beneficial effects in the mouse model.Jahnke VE, Van Der Meulen JH, Johnston HK, Ghimbovschi S, Partridge T, Hoffman EP, Nagaraju K. Metabolic remodeling agents show beneficial ef... [Skelet Muscle. 2012] - PubMed - NCBI
5) GW501516 prevents the down-regulation of AMPK caused by a high-fat diet.Barroso E, Rodríguez-Calvo R, Serrano-Marco L, Astudillo AM, Balsinde J, Palomer X, Vázquez-Carrera M. The PPAR
6) Activation of PPAR***948; promotes mitochondrial energy metabolism and decreases basal insulin secretion.Jiang L, Wan J, Ke LQ, Lü QG, Tong NW. Activation of PPAR


Liquid GW1516 30mL 5mg/mL or Liquid GW1516 60mL 5mg/mL
Click to expand...

RUI-products said:
As many are aware GW1516 is one of the most exciting research chemicals currently available. We are proud to now be offering this compound for your research purposes. As always we will try to provide you with as much information possible to ensure the success of your research experiments.

The list of benefits attributed to this compound are quite impressive. It has been successfully used in research to improve such things as obesity, insulin resistance, metabolic syndrome, lipid profile (cholesterol), and cardiovascular disease as well as cardiovascular endurance. The studies referenced at the bottom of this article point out benefit after benefit in all of the above mentioned areas.

As with all research compounds there are direct and indirect side effects. The above mentioned things are all direct effects. GW is a peroxisome proliferator-activated receptor modulator (PRAR Modulator).There are small incidences documented in a very small number of studies with PRAR Modulators with one indirect effect that may be prudent to address. Apparently there is a small increase in the likelihood of research subjects developing stomach polyps. While this is worth being aware of, the good news is in those very same studies it is documented that administration of a COX-2 inhibitor virtually eliminates this increased possibility.

That's great news so what is a COX_2 Inhibitor? It is a type of NSAID, or NON Steroidal Anti Inflammatory Drug. A prescription example of a COX-2 Inhibitor would be the drug Celecoxib. The problem with the administration of a prescription COX-2 Inhibitor is they also contain traditional NSAID effects and should not be frequently administered to research subjects due to a myriad of potential adverse side effects. So what's so good about that news you may ask? Well there is another readily available, inexpensive COX-2 Inhibitor available OTC as a supplement. Tribulus terrestris is an effective COX-2 inhibitor that does not contain the additional forms of NSAIDS that would expose our research subjects to the previously mentioned potential adverse side effects.

To sum it up based on the information above and in the studies referenced below when researching with Liquid GW1516 the addition of the inexpensive supplement tribulus would probably be a prudent investment. Again we are very excited about offering the exceptional compound Liquid GW1516 for use in your research. We will continue to provide you with all the latest information to make your research as safe and successful as possible!


Refs:
*Activation of nuclear hormone receptor peroxisome proliferator-activated receptor-delta accelerates intestinal adenoma growth. Gupta RA, Wang D, Katkuri S, Wang H, Dey SK, DuBois RN
Department of Medicine, The Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, Tennessee 37232-6838, USA. PMID 14758356
*Berger J, Moller DE (2002). "The mechanisms of action of PPARs". Annu. Rev. Med. 53: 409-35. doi:10.1146/annurev.med.53.082901.104018. PMID 11818483
* Peroxisome proliferator-activated receptors, metabolic syndrome and cardiovascular disease. Salman Azhar Future Cardiol. 2010 September; 6(5): 657***8211;691. doi: 10.2217/fca.10.86 PMCID: PMC3246744 NIHMSID: NIHMS345357
* Evaluation of natural products on inhibition of inducible cyclooxygenase (COX-2) and nitric oxide synthase (iNOS) in cultured mouse macrophage cells. Hong CH, Hur SK, Oh OJ, Kim SS, Nam KA, Lee SK Department of Pharmacy, College of Pharmacy, Ewha Womans University, 11-1 Daehyun-dong, Seodaemun-ku, 120-750, Seoul, South Korea Journal of ethnopharmacology 83:1-2 2002 Nov pg 153-9 PMID 12413723
*Lipid effects of peroxisome proliferator-activated receptor-***948; agonist GW501516 in subjects with low high-density lipoprotein cholesterol: characteristics of metabolic syndrome. Olson EJ, Pearce GL, Jones NP, Sprecher DL. Lipid effects of peroxisome pr... [Arterioscler Thromb Vasc Biol. 2012] - PubMed - NCBI
*Metabolic remodeling agents show beneficial effects in the dystrophin-deficient mdx mouse model.Jahnke VE, Van Der Meulen JH, Johnston HK, Ghimbovschi S, Partridge T, Hoffman EP, Nagaraju K. Metabolic remodeling agents show beneficial ef... [Skelet Muscle. 2012] - PubMed - NCBI
Click to expand...

And there you have it ^^^
 
Last edited:
RUI-products said:
What product is that? It's called GW-501516, GW-1516 or GW for short. Over the past months research and feedback into this compound has been booming with positive results and demand has skyrocketed.

Ok so if you don't already know what GW is you may be thinking "what's so special about this compound, spill it already". Well here is a little bit about GW and why I feel it will continue to grow in its research with no slowing down anytime soon.

GW affects the peroxisome proliferator receptor (PPR) in the body and is considered a compound in a class called peroxisome proliferator activated receptor modulators (PPARM's). This is very important because PPAR's effect many biological processes in the body.

GW has a wide variety of effects in the body such as cell energy metabolism, insulin secretion, fatty acid oxidation, and even affects muscle inflammation and damage (in a positive way). In energy metabolism GW was shown to improve mitochondrial morphology in palmitate treated b-cells and this showed to heighten the energy levels in research subjects.

This GW compound is an amazing compound to work with for many reasons, but the main one that is being talked about right now and that researchers are raving about is GW's fat-loss enhancing abilities! GW shows these abilities on many different levels. It will not only higher the test subjects metabolism leading the way to enhanced fat-loss, but will also change the way the body handles fat in the blood and how insulin is released into the body. All these positive findings are what give GW its amazingly powerful fat-loss enhancing qualities. These findings have shown that GW may even be a possible future treatment for various diseases and is currently being looked at for treating diseases such as dyslipidemia and obesity.

GW has also been found to play a role in the development of some diseases like diabetes and obesity amongst many others. To me that means the research of GW may also open doors to possible ways of treating some diseases never thought of before, it really is interesting and promising in this regard.

Aside from its well-known fat-loss enhancing qualities, GW has been shown to have many protective qualities as well. GW has been shown in research to have muscular protective and enhancing effects and this seems to be related to a decrease in muscle inflammation and damage. GW has also showed an increase in the muscular weight of the research subjects that were subjected to these tests.

GW has shown to elicit cardiovascular protection possibly due to its actions in decreasing insulin spikes as found in current research. This leads me to believe that the cardio protective actions found in GW in research subjects with obesity are not only related to the fat-loss enhancing qualities of GW itself but also its positive effects on insulin secretion and also its effects on dyslipidemia. GW shows its positive effects in dyslipidemia by preventing the down-regulation of AMPK that can be caused by high fat or subpar diets. GW does this by amplifying the PGC-1a-Lipin 1-PPAR pathway and this gives rise to increased fatty acid oxidation in the blood. To put it simply it can lower cholesterol levels in most settings of research and of course we know high cholesterol levels can negatively impact heart health.

With GW offering muscular protection and enhancement, along with obviously extreme abilities in enhancing fat-loss, I just don't see GW research slowing down anytime soon and the feedback from researchers has been wonderful. I am happy to now have enough research data on GW-1516 to put this article together for you all, explaining the many known benefits to GW research. I hope that this opens the door to other researchers expanding the already well-established data on GW and finding new possible uses or explanations for its actions. This is an amazing compound and I hope that this article has shed some light onto GW's amazing abilities and that the research continues to grow as it currently is!

Check it out >> Liquid GW1516 30mL 5mg/mL or Liquid GW1516 60mL 5mg/mL

Refs:
1) Lipid effects of GW501516 in subjects.Olson EJ, Pearce GL, Jones NP, Sprecher DL. Lipid effects of peroxisome pr... [Arterioscler Thromb Vasc Biol. 2012] - PubMed - NCBI
2) PPAR in humans: genetic and pharmacological evidence for a significant metabolic functions.Karpe F, Ehrenborg EE. PPARdelta in humans: genetic and pharmacol... [Curr Opin Lipidol. 2009] - PubMed - NCBI
3) Mechanism of action of a peroxisome proliferator-activated receptor agonist on lipoprotein metabolism in dyslipidemic subjects.Ooi EM, Watts GF, Sprecher DL, Chan DC, Barrett PH. Mechanism of action of a peroxisome ... [J Clin Endocrinol Metab. 2011] - PubMed - NCBI
4) Metabolic remodeling agents show beneficial effects in the mouse model.Jahnke VE, Van Der Meulen JH, Johnston HK, Ghimbovschi S, Partridge T, Hoffman EP, Nagaraju K. Metabolic remodeling agents show beneficial ef... [Skelet Muscle. 2012] - PubMed - NCBI
5) GW501516 prevents the down-regulation of AMPK caused by a high-fat diet.Barroso E, Rodríguez-Calvo R, Serrano-Marco L, Astudillo AM, Balsinde J, Palomer X, Vázquez-Carrera M. The PPAR
6) Activation of PPAR***948; promotes mitochondrial energy metabolism and decreases basal insulin secretion.Jiang L, Wan J, Ke LQ, Lü QG, Tong NW. Activation of PPAR


Liquid GW1516 30mL 5mg/mL or Liquid GW1516 60mL 5mg/mL
Click to expand...

RUI-products said:
As many are aware GW1516 is one of the most exciting research chemicals currently available. We are proud to now be offering this compound for your research purposes. As always we will try to provide you with as much information possible to ensure the success of your research experiments.

The list of benefits attributed to this compound are quite impressive. It has been successfully used in research to improve such things as obesity, insulin resistance, metabolic syndrome, lipid profile (cholesterol), and cardiovascular disease as well as cardiovascular endurance. The studies referenced at the bottom of this article point out benefit after benefit in all of the above mentioned areas.

As with all research compounds there are direct and indirect side effects. The above mentioned things are all direct effects. GW is a peroxisome proliferator-activated receptor modulator (PRAR Modulator).There are small incidences documented in a very small number of studies with PRAR Modulators with one indirect effect that may be prudent to address. Apparently there is a small increase in the likelihood of research subjects developing stomach polyps. While this is worth being aware of, the good news is in those very same studies it is documented that administration of a COX-2 inhibitor virtually eliminates this increased possibility.

That’s great news so what is a COX_2 Inhibitor? It is a type of NSAID, or NON Steroidal Anti Inflammatory Drug. A prescription example of a COX-2 Inhibitor would be the drug Celecoxib. The problem with the administration of a prescription COX-2 Inhibitor is they also contain traditional NSAID effects and should not be frequently administered to research subjects due to a myriad of potential adverse side effects. So what’s so good about that news you may ask? Well there is another readily available, inexpensive COX-2 Inhibitor available OTC as a supplement. Tribulus terrestris is an effective COX-2 inhibitor that does not contain the additional forms of NSAIDS that would expose our research subjects to the previously mentioned potential adverse side effects.

To sum it up based on the information above and in the studies referenced below when researching with Liquid GW1516 the addition of the inexpensive supplement tribulus would probably be a prudent investment. Again we are very excited about offering the exceptional compound Liquid GW1516 for use in your research. We will continue to provide you with all the latest information to make your research as safe and successful as possible!


Refs:
*Activation of nuclear hormone receptor peroxisome proliferator-activated receptor-delta accelerates intestinal adenoma growth. Gupta RA, Wang D, Katkuri S, Wang H, Dey SK, DuBois RN
Department of Medicine, The Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, Tennessee 37232-6838, USA. PMID 14758356
*Berger J, Moller DE (2002). "The mechanisms of action of PPARs". Annu. Rev. Med. 53: 409–35. doi:10.1146/annurev.med.53.082901.104018. PMID 11818483
* Peroxisome proliferator-activated receptors, metabolic syndrome and cardiovascular disease. Salman Azhar Future Cardiol. 2010 September; 6(5): 657–691. doi: 10.2217/fca.10.86 PMCID: PMC3246744 NIHMSID: NIHMS345357
* Evaluation of natural products on inhibition of inducible cyclooxygenase (COX-2) and nitric oxide synthase (iNOS) in cultured mouse macrophage cells. Hong CH, Hur SK, Oh OJ, Kim SS, Nam KA, Lee SK Department of Pharmacy, College of Pharmacy, Ewha Womans University, 11-1 Daehyun-dong, Seodaemun-ku, 120-750, Seoul, South Korea Journal of ethnopharmacology 83:1-2 2002 Nov pg 153-9 PMID 12413723
*Lipid effects of peroxisome proliferator-activated receptor-***948; agonist GW501516 in subjects with low high-density lipoprotein cholesterol: characteristics of metabolic syndrome. Olson EJ, Pearce GL, Jones NP, Sprecher DL. Lipid effects of peroxisome pr... [Arterioscler Thromb Vasc Biol. 2012] - PubMed - NCBI
*Metabolic remodeling agents show beneficial effects in the dystrophin-deficient mdx mouse model.Jahnke VE, Van Der Meulen JH, Johnston HK, Ghimbovschi S, Partridge T, Hoffman EP, Nagaraju K. Metabolic remodeling agents show beneficial ef... [Skelet Muscle. 2012] - PubMed - NCBI
Click to expand...
Great research product ^^^
 
Running is the best exercises because it helps you burn the calories, Walking, Sprinting and adding hills or an incline can burn 180 calories in 30 minutes, Bicycling and Swimming of 30 minutes can burn 400 to 500 calories....

Dublin fitness
 
Last edited:
Algernon said:
Running is the best exercises because it helps you burn the calories, Walking, Sprinting and adding hills or an incline can burn 180 calories in 30 minutes, Bicycling and Swimming of 30 minutes can burn 400 to 500 calories....

Dublin fitness
Click to expand...
 
halfwit said:
I'm still looking into dosages and side effects, etc. If anyone has information on these, it would be appreciated! :)
Click to expand...

I found a log that suggests 5-10mg/day. The guy started at 5 and ran for a bit and is now upping to 10. He reports definite increased cardio capacity so far.
 
I like it, even many of us like this..
Algernon, I like your post here, thanks to showing here calorie little chart.. I'll do follow the exercises and other activities now..
 
Last edited:
hurricane187 said:
2o mg a day is best dosage..gw is an amazing product
Click to expand...
Damn, that is definitely going to make it an expensive chem to run. I've been experimenting with 5mg/ED but think it's too early to tell after a week and a half if it's doing much for my rats.
 
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