Having some high estrogen symptoms, need some advice please.

[SilverBackGorilla]

Been experiencing some high estrogen symptoms, most notably night sweats and low libido. Went to the doctor and he ran bloodwork and here are the results. My current protocol is 120mg test cyp and .5mg of anastrozole every 3.5 dsys. I would appreciate any help in adjusting my dosage please. Thank you. P.S. next injection is Monday morning.

 

[A.B]

I cant view the links but if your estrodial is higher and even out of the reference range I would run your AI EOD and get blood checked in another 2-3 weeks

 

[Megatron28]

Your E2 isn't crazy high. But things you could consider trying are:

Lower Test dosage from 240mg/week to 200mg/week.

Increase AI dosage slightly.

Try Aromasin instead of Anastozole to see if it works better for you

Add in some DIM to your protocol. Normally this wouldn't likely do much, but it might be just enough to tip the scales.

Try pinning more frequently.

Try doing subcutaneous injections. You would have to do smaller doses more frequently.

 

[SilverBackGorilla]

I have started taking the adex every other day at .5mg. I will report back in a few weeks with how i feel and after i get tested again. Thanks guys.

 

[Megatron28]

I have started taking the adex every other day at .5mg. I will report back in a few weeks with how i feel and after i get tested again. Thanks guys.

Increasing your AI dosage 75% (1.75mg/wk vs. 1.00mg/wk) seems like a lot given that your E2 isn't crazy high.

 

[956Vette]

I have started taking the adex every other day at .5mg. I will report back in a few weeks with how i feel and after i get tested again. Thanks guys.

Highly recommend against taking this much adex. Switch to nolvadex instead.

 

[SilverBackGorilla]

Increasing your AI dosage 75% (1.75mg/wk vs. 1.00mg/wk) seems like a lot given that your E2 isn't crazy high.

Just a quick report so far, i do feel better and the night sweats have stopped. Embarrassingly enough, i have actually had a morning erection which hasn't happened for a while. Could you suggest a different anastrozole schedule than what I'm using? Its what i have to work with.

 

[Megatron28]

Highly recommend against taking this much adex. Switch to nolvadex instead.

Nolvadex isn't an Aromatase Inhibitor.

 

[scorob777]

A couple things of note for me. Taking 240 mg/wk of testosterone should put you well over the figure you posted. Was that blood test taken not long after starting this? It would take you about eight weeks to hit a new plateau after changing your dose.

In my opinion that's way too much test. It's well beyond normal TRT, and well too low for bodybuilding. Kind of a why bother type dosage in terms of bodybuilding, and an asking for trouble dosage for TRT (meaning you'll have to manage estrogen with an AI which sucks).

And next that adex dosage is huge. Some people taking 500 mg/wk on a cycle use that much adex. In my opinion way too much for your dose, but before I'd sweat that detail of trying to normalize E2 at a 240mg/wk dosage I would suggest cutting your test dosage in half.

At 120 mg/wk total you might not need any adex, which I think is a good goal to have. Using AI's just plain sucks and can have other side effects.

 

[SilverBackGorilla]

A couple things of note for me. Taking 240 mg/wk of testosterone should put you well over the figure you posted. Was that blood test taken not long after starting this? It would take you about eight weeks to hit a new plateau after changing your dose.

In my opinion that's way too much test. It's well beyond normal TRT, and well too low for bodybuilding. Kind of a why bother type dosage in terms of bodybuilding, and an asking for trouble dosage for TRT (meaning you'll have to manage estrogen with an AI which sucks).

And next that adex dosage is huge. Some people taking 500 mg/wk on a cycle use that much adex. In my opinion way too much for your dose, but before I'd sweat that detail of trying to normalize E2 at a 240mg/wk dosage I would suggest cutting your test dosage in half.

At 120 mg/wk total you might not need any adex, which I think is a good goal to have. Using AI's just plain sucks and can have other side effects.

Hey, I really appreciate all the comments. I failed to mention that I have been suffering from anxiety and depression for a while now and they just recently put me on a low dose Effexor which is an antidepressant. The symptoms i am having are most likely from the new drug rather than the Test/Adex dosage. Never know though.

Admittedly I have always kind of pushed the "TRT" dosage amount per week. My longtime doc thought it was ok to do 240 a week so i have now for a while. A big reason for the anxiety and depression is i went through a divorce, lost my job, and several other things that have really euined my happiness. Admittedly its been about 3 years since ive been in the gym and i have gained some weight and definitely lost muscle. I have a home gym i can do some stuff with so i am going to start doing that.


Now. About my dosage. I did do the 240mg wk test and .5mg adex eod for one week and thought inwas feeling better but i read what you guys posted and 3.5 days ago i shot 100mg with no adex. I am due a shot this evening and was contemplating doing 100mg ever 3.5 days with .25mg adex with each shot. I understand whag you are saying about getting off the A.I. with a low dose test, i get it. The thing is i already suffer from ED and i am worried the lower test will make things worse. I have cialis on the way, i let myself run out.


I know this is a lot to digest and i really appreciate everyone taking the time to help me and to maybe understand how depression and anxiety can really screw someone up. Its tough to tell if E2 symptoms are feom the depression, the meds, or the E2. Mostly i want my sex drive back, i can handle everything else. I did drop the Effexor a few days ago. Too many unwanted side effects. We are looking into a med that had no ED sides, maybe Welbutrin.

Thank you all.
SBG


UGH, I forgot to add that my doctor also writes me for 2X per week of 500units of HCG. I have been shooting 150 units each night because i read that it is s more natural way for your body to uptske it. Can't say i feel better on any particular dosage. For the longest time i ran 250units 2X a week along with my test shot. Am i taking too much of that or dosing it wrong? I am all ears on what to do next.

 

[Nicky_eye_lids]

so sorry to hear your going through a hard time. Antidepressants are always a problem since they treat the issue and not help you out of it.

change in lifestyle, new hobbies, staying off drugs and alcohol, taking up yoga, new fitness workout schedule, better diet, always has helped others deal with depression and anxiety instead of getting hooked on antidepressants which is worst that being on heroin since the side effects are just the same and make you numb to the world around you.

i dont like being numb and insensitive. I like to be in control of myself and my surroundings. I had to make big changes in my life before i could feel like this as well and it has all been worth it. Man, many peoplke I know have even started going to church to feel better and it works for them and way cheaper than taking pills to feel better.

Hope you get better and can sort out your life brotherman, and we are all here cheering for you that you will!!!

 

[scorob777]

Hey, I really appreciate all the comments. I failed to mention that I have been suffering from anxiety and depression for a while now and they just recently put me on a low dose Effexor which is an antidepressant. The symptoms i am having are most likely from the new drug rather than the Test/Adex dosage. Never know though.

Admittedly I have always kind of pushed the "TRT" dosage amount per week. My longtime doc thought it was ok to do 240 a week so i have now for a while. A big reason for the anxiety and depression is i went through a divorce, lost my job, and several other things that have really euined my happiness. Admittedly its been about 3 years since ive been in the gym and i have gained some weight and definitely lost muscle. I have a home gym i can do some stuff with so i am going to start doing that.


Now. About my dosage. I did do the 240mg wk test and .5mg adex eod for one week and thought inwas feeling better but i read what you guys posted and 3.5 days ago i shot 100mg with no adex. I am due a shot this evening and was contemplating doing 100mg ever 3.5 days with .25mg adex with each shot. I understand whag you are saying about getting off the A.I. with a low dose test, i get it. The thing is i already suffer from ED and i am worried the lower test will make things worse. I have cialis on the way, i let myself run out.


I know this is a lot to digest and i really appreciate everyone taking the time to help me and to maybe understand how depression and anxiety can really screw someone up. Its tough to tell if E2 symptoms are feom the depression, the meds, or the E2. Mostly i want my sex drive back, i can handle everything else. I did drop the Effexor a few days ago. Too many unwanted side effects. We are looking into a med that had no ED sides, maybe Welbutrin.

Thank you all.
SBG


UGH, I forgot to add that my doctor also writes me for 2X per week of 500units of HCG. I have been shooting 150 units each night because i read that it is s more natural way for your body to uptske it. Can't say i feel better on any particular dosage. For the longest time i ran 250units 2X a week along with my test shot. Am i taking too much of that or dosing it wrong? I am all ears on what to do next.

I'm a huge fan of HCG, so I can't say you are taking too much. I would say though that 240 mg/wk test plus 1,050 IU/w HCG is going to put you so high that you may be having ED symptoms from that, i.e. too high test, and you for sure are well up into producing lots of E2 hence the need for all that adex.

I repeat my opinion is you'll be better all around if you can get a test dose low enough you don't need the adex. With all that HCG you might be surprised how low. I wouldn't be surprised at all if 70mg/wk test plus all that HCG would be more than enough.

I've had experiences in the past where I've had ED from taking too much test. These were body builder doses, well above what you are taking, and also with HCG at 500 IU 2x/wk. More test did not help, in fact seemed to hinder. What got things going again was a detox cruise for several months at 100 mg/wk Test E, with HCG, without any AI.

Try a much lower dose for a while. Ditch the adex. See if your morning wood comes back. That's the best indicator

 

[SilverBackGorilla]

I'm a huge fan of HCG, so I can't say you are taking too much. I would say though that 240 mg/wk test plus 1,050 IU/w HCG is going to put you so high that you may be having ED symptoms from that, i.e. too high test, and you for sure are well up into producing lots of E2 hence the need for all that adex.

I repeat my opinion is you'll be better all around if you can get a test dose low enough you don't need the adex. With all that HCG you might be surprised how low. I wouldn't be surprised at all if 70mg/wk test plus all that HCG would be more than enough.

I've had experiences in the past where I've had ED from taking too much test. These were body builder doses, well above what you are taking, and also with HCG at 500 IU 2x/wk. More test did not help, in fact seemed to hinder. What got things going again was a detox cruise for several months at 100 mg/wk Test E, with HCG, without any AI.

Try a much lower dose for a while. Ditch the adex. See if your morning wood comes back. That's the best indicator

I am going to take your advice starting right now. I am taking my shot right now as i type this. When i did my shot of 100mg 3.5 days ago i also switched back to doing my HCG twice a week when i do my test shots and only at 250iu for a total of 500iu a week. Doc writes me for 1000iu a week which it what made me do 150iu each night to keep it more stable but i have been told its too much. I know i have been really wrong and not doing myself any good bouncing around and chasing symptoms. I was actually thinking my bloodwork was not too bad but you really are more than likely right and that my test is way too high and is causing me ED problems. So for tonight i will inject 50mg test cyp with 250iu HCG and no Anastrozole. I will do the same thing 3.5 days from now and so on and so on if that seems ok to you. If you really think i should go less then we can adjust for my next shot. I want to say again how thankful i am for the help. And how appreciative i will be if you all keep following this thread until we see some good numbers and i feel better most importantly. Maybe a lot of my depression and anxiety is linked to too high of test in my system. I just want to feel better and have my sexual desire back. Thank you all again.

I'd like to add another comment on the HCG amount. I have no problem keeping at 1050iu a week if you think thats best to do. I do not know a ton about it but i can tell you i have small pituitary tumors and the doctor thought hcg would be of some help keeping it functioning to some degree. I will say that on 150iu each noght my testicles don't seem as full as i would think they would be. I'm all ears on what i should do with the HCG dosage though. As i said, i did 250iu 3.5 days ago and again tonight for a weekly total of 500iu for the week. I could do 250iu EOD which is what its actually written as or 500iu every 3.5 days, I'm open to whatever.

 

[SilverBackGorilla]

Just an update... did another shot tonight, 50mg test cyp, no A.I. and 250 iu HCG. No morning wood yet. Really need to get my CPAP script updated come to think if it. Still off my Effexor antidepressant.

 

[scorob777]

How old did you say you are? I'm over 50 and take HCG 500 IU 2x/wk. 250 2x/wk seems a bit low to me, for my age anyway. For younger guys it's enough.

It will take five or six weeks for your testosterone levels to bleed down to a new steady state, so don't expect things to happen overnight.

I think 50 mg Test 2x/wk - total 100 mg/wk and 500 IU HCG 2x/wk - total 1,000 IU/wk is a very reasonable dosage.

For me personally that would put me at 650ish total testosterone, and estrogen would be in range in the high 20's to 30's without AI. But that's me. You'll have to come to a new steady state and get tested.

Maybe get bloodwork at 6 weeks, then again at 8, and 10. See how you feel and adjust things up or down from there.

Good luck. Get in the gym. That on top of getting your levels normalized should make you feel a lot better.

 

[SilverBackGorilla]

How old did you say you are? I'm over 50 and take HCG 500 IU 2x/wk. 250 2x/wk seems a bit low to me, for my age anyway. For younger guys it's enough.

It will take five or six weeks for your testosterone levels to bleed down to a new steady state, so don't expect things to happen overnight.

I think 50 mg Test 2x/wk - total 100 mg/wk and 500 IU HCG 2x/wk - total 1,000 IU/wk is a very reasonable dosage.

For me personally that would put me at 650ish total testosterone, and estrogen would be in range in the high 20's to 30's without AI. But that's me. You'll have to come to a new steady state and get tested.

Maybe get bloodwork at 6 weeks, then again at 8, and 10. See how you feel and adjust things up or down from there.

Good luck. Get in the gym. That on top of getting your levels normalized should make you feel a lot better.

Hey, thanks for the reply!!! I am 50 this month. I will keep my test dosage at 50mg for my next shot in a couple days and up my HCG to 500i.u. like you suggest. Could you help me pick out a bloodwork panel through PrivateMDlabs to have done in a few weeks? If i recall when i got into all this that my free testosterone was quite high for the low amount of test i was taking when i first started TRT. I was told that's a good thing. I'd like to have my free testosterone checked as well as my SHBG. Any other things besides total testosterone ans Sensitive E2 i should have tested? Again, thank you all so much!!!

 

[appleton111]

Hey, thanks for the reply!!! I am 50 this month. I will keep my test dosage at 50mg for my next shot in a couple days and up my HCG to 500i.u. like you suggest. Could you help me pick out a bloodwork panel through PrivateMDlabs to have done in a few weeks? If i recall when i got into all this that my free testosterone was quite high for the low amount of test i was taking when i first started TRT. I was told that's a good thing. I'd like to have my free testosterone checked as well as my SHBG. Any other things besides total testosterone ans Sensitive E2 i should have tested? Again, thank you all so much!!!

basically the female panel covers all those area if im not mistaken. but megatron, tankman, old musclemike, Jpflex and other vets may advice you better.

 

[appleton111]

Hey, thanks for the reply!!! I am 50 this month. I will keep my test dosage at 50mg for my next shot in a couple days and up my HCG to 500i.u. like you suggest. Could you help me pick out a bloodwork panel through PrivateMDlabs to have done in a few weeks? If i recall when i got into all this that my free testosterone was quite high for the low amount of test i was taking when i first started TRT. I was told that's a good thing. I'd like to have my free testosterone checked as well as my SHBG. Any other things besides total testosterone ans Sensitive E2 i should have tested? Again, thank you all so much!!!

View attachment 567871 and Happy Bday my friend!!!! Hope you have a great one and lots of cake.

 

[scorob777]

The standard female hormone panel won't give you free T or SHBG. Also is not sensitive E2. It's the cheap and cheerful version, good enough for ballpark numbers when you are trying to settle in.

Once you reach a steady state and want to get higher quality results then add those things in. I know there is one a step up that includes the sensitive E2 and LCMS testosterone. It's another step up to get the free T and SHBG. You just have to read through their options and find the one you want