Glucosamine does it for me.
Now I'm trying glucosamine and chondoitin, 500mg + 200mg, two times a day. No pain.
But I wasn't having pain with glucosamine only 750mg two times a day.
Somebody told me that over 500mg didn't make a difference, but I never saw a study concluding something about dose-related effiency of glucosamine.
The only thing I'm sure of is that glucosamine does make a difference for me and many people in joint recovery and pain.