Mitigating suppression while on LGD

G

gayeyes

New member
Hey guys,

I'm almost two weeks into my LGD-only cycle at 5 mg ED and so far I don't feel suppressed and sexual performance is normal. As I'm about to up my dose to 7.5 mg I want to see how I can mitigate suppression as much as possible. Any ideas? I have clomid and nolva ready for my PCT but I'm wondering if there's anything I could start now to ensure that the last 2-3 weeks of the cycle are not pure misery due to low T :)

Appreciate any suggestions or ideas!
 
Tell you what, if you can figure out how to beat the negative feedback loop of the HPTA, you will become a very rich man. :)

I won't pretend to know much about SARMs, but I know a few things about how our bodies work with suppression. If anyone tries to sell you something to prevent this, they're ripping you off, plain and simple.

My .02c :)
 
I hear you, and I realize maybe I wasn't precise enough in my language :) I realize suppression is inevitable, but I wanted to find out how to mitigate the effects like lethargy and loss of libido. I've researched Dermacrine and I started it 3 days ago. It may be too soon but I do feel that lethargy has diminished... Thursday was a killer but yesterday was a lot better already. I'll keep rubbing and will report back.
 
1mg of LGD is enough to fully suppress the HPTA system - so you are certainly suppressed. The only way to ensure you keep your test levels up to normal is to inject test. However, you can reduce the side effects of the low test (which is what you are looking to do). For the lethargy, I found that nothing beats GW50 (a PPAR Agonist sold by SARMs makers). The GW50 from SarmsSearch is legit, I have used it many times.

As for the libido - not sure what to tell you there. Look at a bunch of Tentacle Porn maybe...and take Cialis. But in seriousness, a combination of Cialis and PT141 (a peptide) work wonders in obtaining and maintaining an erection. Cialis works on the blood flow portion and PT141 works on the electrical signaling portion. PT141 is a SubQ injection.
 
cybrsage said:
1mg of LGD is enough to fully suppress the HPTA system - so you are certainly suppressed. The only way to ensure you keep your test levels up to normal is to inject test. However, you can reduce the side effects of the low test (which is what you are looking to do). For the lethargy, I found that nothing beats GW50 (a PPAR Agonist sold by SARMs makers). The GW50 from SarmsSearch is legit, I have used it many times.

As for the libido - not sure what to tell you there. Look at a bunch of Tentacle Porn maybe...and take Cialis. But in seriousness, a combination of Cialis and PT141 (a peptide) work wonders in obtaining and maintaining an erection. Cialis works on the blood flow portion and PT141 works on the electrical signaling portion. PT141 is a SubQ injection.
Click to expand...

Thanks cybr! What's your opinion on Dermacrine?
 
gayeyes said:
Hey guys,

I'm almost two weeks into my LGD-only cycle at 5 mg ED and so far I don't feel suppressed and sexual performance is normal. As I'm about to up my dose to 7.5 mg I want to see how I can mitigate suppression as much as possible. Any ideas? I have clomid and nolva ready for my PCT but I'm wondering if there's anything I could start now to ensure that the last 2-3 weeks of the cycle are not pure misery due to low T :)

Appreciate any suggestions or ideas!
Click to expand...

Keep us posted!
 
gayeyes said:
Thanks cybr! What's your opinion on Dermacrine?
Click to expand...

I have not had much luck with transdermals - I have bad reactions to most of the carrier agents.

I would go with HCG 250 twice a week as franco suggested - it will keep your boys plump and ready to move into PCT when you enter it. Just stop prior to entering PCT.
 
gayeyes said:
Hey guys,

I'm almost two weeks into my LGD-only cycle at 5 mg ED and so far I don't feel suppressed and sexual performance is normal. As I'm about to up my dose to 7.5 mg I want to see how I can mitigate suppression as much as possible. Any ideas? I have clomid and nolva ready for my PCT but I'm wondering if there's anything I could start now to ensure that the last 2-3 weeks of the cycle are not pure misery due to low T :)

Appreciate any suggestions or ideas!
Click to expand...

Your test levels will bounce back on their own. I was on 10mg - 20mg LGD for 5 weeks total my test bounced back at over 150% within a few days, blood test confirmed. I took 12.5mg Clomid daily starting immediately after the blood was drawn (I didn't want to skew the blood test). The Clomid was to prevent any gyno from the bounce back test levels. 12.5 my was enough. At the doses you are at you may have suppression but it's not shutdown like with AAS. Just don't brush off the suppression, do a normal pct at 4 weeks and don't go over 8 weeks on cycle.
 
Thanks for all the responses, guys. I'm now about to enter week 6 of LGD at 12 mg per day. Last week I did mid-cycle bloods and (no surprise) I'm very suppressed. Total Test is 98 ng/dL, and LH and FSH are at the very bottom of the range, both at 1.5 mIU/mL. The interesting thing is that I feel just fine - no lethargy, no lack of mental focus, normal energy levels, no perceptible shrinkage downstairs, etc. I've been using Dermacrine at 3 pumps per day which is probably helping keep my test at a "survival" level. Even my libido, while not through the roof, is OK, I'm able to perform and even get the occasional morning wood.

The cycle is going fantastic - I'm up 8 lbs and visibly bigger and full. I may also be a bit leaner even though I'm eating about 300-400 cals above maintenance. Performance in the gym is incredible - all my lifts are up 10-15% and endurance is excellent with a lot less rest time between sets. In fact I'm enjoying this so much that I'm thinking of extending the run for a couple extra weeks for total of 10. Any strong feelings against this?

I'm prepared to do a full 4-week PCT with Clomid and Nolva and I'm confident that my test will bounce back nicely.

My only concern is that my liver enzymes are a bit elevated (AST=43, ALT=74). I didn't know LGD was hard on the liver and did not plan proper liver support. I'm thinking of starting UDCA to heal and then run NAC through PCT. Thoughts? Also (expected) my HDL is pretty low at 28, although total cholesterol is still well within range at 152.

Keep the comments coming, guys, much appreciated.
 
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LGD is not hard on the liver, or at least none of the medical studies show any liver enzyme changes during their studies. It most likely is from something else, even something like you are now working your body harder so your liver must work harder to clean up the toxins you are making.

UDCA (or TUDCA, TUDCA is UDCA with taurine added and is available over the counter) is a good healing choice, but you can run NAC along side it with no issues if you wish.
 
LGD is an interesting compound. I def think its great on a cycle. I mean if your gonnause HCG to stave off the significant suppression that comes with LGD IMO you should just use test. Thats me, its a personal choice however. Now LGD is very harsh on lipid profile. Its something you need to be aware of. SARMS are excellent but they all have their side effects, they just differ from the sides of steroids in some cases. For example with s4 its vision. With LGD its significant suppression (to the point of shutdown depending on dosage) and lipids. Thats why its important people educate themselves on SARMS so they can be used properly. Dont buy into the "no sides"claims some of the irresponsible sarms vendors you see on other forums make. They ALL def have sides, its important to educate yourself as to what the sides are so you can use them appropriately. I think sarms def have a place in this lifestyle and when used properly they can be an awesome addition to an anabolic cycle. Thats where I personally see them as being most valuable.
 
cybrsage said:
LGD is not hard on the liver, or at least none of the medical studies show any liver enzyme changes during their studies. It most likely is from something else, even something like you are now working your body harder so your liver must work harder to clean up the toxins you are making.
Click to expand...

This is interesting. Do you think that the extra intensity at the gym is enough to raise the enzyme levels to the values I'm seeing (AST=43, ALT=74)? And -- are these values high enough to be a concern?
 
gayeyes said:
This is interesting. Do you think that the extra intensity at the gym is enough to raise the enzyme levels to the values I'm seeing (AST=43, ALT=74)? And -- are these values high enough to be a concern?
Click to expand...

The AST is barely out of range, so no worries there. The ALT is quite high. What is your bilirubin level? A high bilirubin level in conjunction with the high AST and ALT could show real trouble. Do you also drink alcohol?

If you drink alcohol, stop drinking it while working out hard. It is not good for the liver in any way shape or form and the liver is already stressed. Add the NAC and UDCA / TUDCA to your supplements and test your blood again in a month to see if they went down.
 
cybrsage said:
The AST is barely out of range, so no worries there. The ALT is quite high. What is your bilirubin level? A high bilirubin level in conjunction with the high AST and ALT could show real trouble. Do you also drink alcohol?

If you drink alcohol, stop drinking it while working out hard. It is not good for the liver in any way shape or form and the liver is already stressed. Add the NAC and UDCA / TUDCA to your supplements and test your blood again in a month to see if they went down.
Click to expand...

Total bilirubin is really low at 0.4 mg/dL -- and unchanged from the baseline bloods I did before starting. I barely drink - maybe 1-2 drinks a month if that and I haven't at all since starting the cycle.

All I'm taking is LGD and MK-677. You stated before that LGD is not hard on the liver, and in all my research I haven't seen a mention of MK being problematic either... so the question remains, what could be causing the elevated values? Just working out harder?

I'm ordering UDCA from RUI as we speak. What is a good brand of NAC besides what RUI carries? I'll report back after my next test.

Thanks for your comments and guidance, much appreciated.
 
From my research lgd isn't very harsh on the liver. But what others experience while on lgd or any sarm for that matter may and will probably be different for you everyone is different. I've seen lots run it with test and really love it.
 
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