Question on injections in the muscle or fat.

[Die$eL~Man]

Its called intramuscular for a reason guys. Whoever thinks fat can absorb it is retarded...

 

[Austinite]

Its called intramuscular for a reason guys. Whoever thinks fat can absorb it is retarded...

I really wish folks would refrain from name calling. Intramuscular is merely a form of injections. Compounds do not evaporate in the body. Everything is absorbed. This isn't random, it's how the human body works and has been proven well over 100 years ago. There are well over 100,000 clinical trials and systematic reviews that conclude this. There isn't anything relating to injections that is more simple than this concept.

 

[DreDay187]

My hypothesis is that yes, any injection will absorb. Will it absorb favorably, giving you all of the test/mg the same as a muscle infection would? Highly doubt it. There's a reason doctors have you hit the muscle. There's a reason us dope fiends like myself hit the vein. Everything is specific.

In medicine only intravenous injections are considered 100% bioavailable or absorbed. Intramuscular injections have slightly less bioavailability bc they must pass through capillary membranes and subcutaneous Injections have slightly less availability bc of the poorer blood flow found in fat and having to pass through another layer of membrane.

The reAson dope fiends and certain medications are injected intravenously is bc they need immediate systemic circulation. This is beneficial in the form of blood transfusions, volume expanders such as saline solution, buffered solutions to treat acidosis or alkalosis, nutritional things like amino acids or vitamins. For the fiends it's the preferred method of use bc it provides instant systemic circulation meaning they get the immediate intense high. There's no waiting for it to absorb. Also compounds that have a molecular mass of greater than 20,000 g/mol move extremely slow through capillary membranes shifting absorption to the lymphatic system. When this happens drug absorption is lessened bc of first pass metabolism in the lymphatics. Obviously for these compounds you'd want intravenous Injections.

Steroids are designed to be administered intramuscularly and can be administered subcutaneously bc their molecular mass is less than 20,000g/mol, they're lipid based making them easier to pass through membranes, and the instant systemic circulation of the steroids like you'd find in intravenous injections is neither warranted nor desired bc stability of serum levels is what we want and the ester attached to the molecule would delay metabolism regardless. Usually medications with extremely short half lives are done intravenously bc of the quick absorption and this necessitates the drip chamber you often see which prevents air from entering your system and giving you an embolism. We typically have a propionate, enanthats, or cypionate ester attached to testosterone which defeats the purpose of injecting intravenously and it also causes unnecessary risk and discomfort. Try injecting in your vein and tell me how you feel afterwards?

Finally, subcutaneous and intramuscular have different absorption rates but similar bioavailability. One is faster than the other. You can inject it anyway you want to but intramuscular gives us great absorption time and is less risky than going in a vein. Sub q isn't as invasive but absorption is slowed. You also you shouldn't inject more than .6ml I believe Into fat which makes IM injections the most common.