Sleep Apnea Linked To Decreased Libido, According To New Study

liftsiron

Community Veteran, Longtime Vet
This is interesting as it goes aginast the grain of some previous studies.


Sleep Apnea Linked To Decreased Libido, According To New Study
HAIFA, ISRAEL and NEW YORK, NY, July 30, 2002 -- Male patients who suffer from obstructive sleep apnea (OSA) -- the inability to breathe properly during sleep -- produce lower levels of testosterone, resulting in decreased libido and sexual activity, according to researchers at the Technion-Israel Institute of Technology. Previous studies had indicated that male sleep apnea patients had reported decreased libidos but the studies were unable to establish a scientific link. The current study, reported in the July issue of The Journal of Clinical Endocrinology & Metabolism, found that nearly half the subjects who suffered from severe sleep apnea also secreted abnormally low levels of testosterone throughout the night. "For years we have seen sleep-disorder patients complain of decreased libido but we had no explanation for this phenomenon until now," said Professor Peretz Lavie, head of the Technion Sleep Laboratory and study leader.

Sleep apnea is a respiratory disorder that affects 4%-9% of adult males. Its most common manifestation is loud snoring and it may occur several hundred times throughout the night, resulting in sleep fragmentation and excessive daytime sleepiness. For many years sleep apnea sufferers have complained of decreased libidos, yet previous studies reported that patients' testosterone levels, although low, were within the normal adult male range.

The current study adopted a different methodology. Earlier studies had only measured participants' testosterone levels once after awakening. In this study, subjects were admitted to the Technion Sleep Center for an entire night and were fitted with electrodes and catheters. They were monitored between 7 p.m. and 7 a.m. with blood samples collected every 20 minutes. At 10 p.m., lights were turned off and the participants retired to sleep. Two groups -- one of sleep apnea patients and another of normal controls of similar body weight and age -- were investigated.

The study found that nearly half the sleep apnea patients secreted abnormally low testosterone levels throughout the night.

"Should follow-up studies confirm these findings, then therapeutic intervention of sleep apnea could become a recommended remedy for certain forms of male sexual dysfunction," said Prof. Rephael Luboshitzky, an endocrinologist on the research team. "It is our hope that in the future, by correcting nighttime breathing patterns we will be able to stimulate hormone production and thereby raise libidos."



The Technion-Israel Institute of Technology is Israel's leading scientific and technological center for applied research and education. It commands a worldwide reputation for its pioneering work in computer science, biotechnology, water-resource management, materials engineering, aerospace and medicine. The majority of the founders and managers of Israel's high-tech companies are alumni.
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Neuroendocrine dysfunction in sleep apnea: reversal by continuous positive airways pressure therapy.
- Grunstein RR, Handelsman DJ, Lawrence SJ, Blackwell C, Caterson ID, Sullivan CE
J Clin Endocrinol Metab 1989 Feb;68(2):352-8.

We studied the effects of sleep apnea on neuroendocrine function in a cross-sectional study of 225 consecutive men undergoing sleep studies and in a longitudinal study of 43 men with severe obstructive sleep apnea before and after 3 months of successful treatment with nasal continuous positive airways pressure to eliminate upper airways obstruction. Blood samples were collected at 0600-0630 h on awakening for measurement of plasma insulin-like growth factor I (IGF-I), total and free testosterone, sex hormone-binding globulin (SHBG), LH, FSH, PRL, T4, T4-binding globulin, and cortisol. The plasma hormone levels were analyzed in relation to the severity of sleep apnea, as indicated by the desaturation index (the hourly rate of episodes of arterial oxygen desaturation greater than 4% of the stable baseline) and the mean minimal oxygen saturation during the desaturation episodes. In the cross-sectional study plasma IGF-I, free and total testosterone, and SHBG levels were significantly lower in relation to the severity of sleep apnea, whereas plasma LH, FSH, PRL, T4, T4-binding globulin, and cortisol were not. The decreases in plasma IGF-I and total and free testosterone were independent of the effects of aging and adiposity by covariance analysis. In the longitudinal study plasma IGF-I, total testosterone, and SHBG, but not free testosterone, significantly increased after 3 months of nasal continuous positive airways pressure treatment. We conclude that sleep apnea causes reversible neuroendocrine dysfunction in men, which is manifested by decreased plasma. IGF-I, testosterone, and SHBG levels. This neuroendocrine dysfunction is related to the severity of the sleep apnea, as indicated by the nadir levels of arterial oxygen desaturation and the rate of desaturation episodes. These hormonal measurements may provide biochemical markers for both the severity of sleep apnea and its response to therapeutic intervention. In addition, sleep apnea may be a previously unrecognized confounder of the neuroendocrine correlates of aging.

This abstract at PubMed.
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If I kept waking up in the middle of REM I'd probably not be too interested in sex too, because I'd be friggin tired all the time! A friend of mine has sleep apnea.
 
great post lifts-- i have sleep apnea-- i use a cpap machine -- without it i feel like shit--

also waking up in the middle of the night gasping for air is no pleasure ontop of that your oxygen levels plummet setting you up for a stroke or heartattack
 
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