DUANABOL
New member
by Cy Willson
Q: I've heard many anti-anxiety and anti-depression meds can have negative bodybuilding consequences when one is also using steroids. Is that true?
A: Caution should be used if one is using anti-anxiety meds like benzodiazepines. The reason? Well, some androgens like Testosterone and stanozolol can prevent these benzodiazepines from binding to receptor sites and thus preventing them from exerting any action. This could cause a severe case of anxiety for that person.
The same thing applies for drugs used to treat depression. Caution should be used with those using SSRI's as some androgens may increase or enhance serotonin levels or their actions. To further complicate things, some can even reduce serotonin levels. Either way, this would require the person to account for this and then readjust his dosage of that particular SSRI.
The same issue applies with MAOI's as androgens like D-bol may increase epinephrine levels. In combination with an MAOI, this could lead to a significant increase in blood pressure and heart rate, and thus could lead to some serious side effects if not monitored closely. The same applies if an androgen increases or decreases MAO levels as this would require one to readjust the dosage.
Now, in reality, there isn't a large risk involved with these drugs and concurrent use of androgens, but caution is warranted and dosages should be adjusted accordingly if the patient finds that the drug or drugs aren't as effective as they were prior to androgen usage. (1-7)
Q: I've heard many anti-anxiety and anti-depression meds can have negative bodybuilding consequences when one is also using steroids. Is that true?
A: Caution should be used if one is using anti-anxiety meds like benzodiazepines. The reason? Well, some androgens like Testosterone and stanozolol can prevent these benzodiazepines from binding to receptor sites and thus preventing them from exerting any action. This could cause a severe case of anxiety for that person.
The same thing applies for drugs used to treat depression. Caution should be used with those using SSRI's as some androgens may increase or enhance serotonin levels or their actions. To further complicate things, some can even reduce serotonin levels. Either way, this would require the person to account for this and then readjust his dosage of that particular SSRI.
The same issue applies with MAOI's as androgens like D-bol may increase epinephrine levels. In combination with an MAOI, this could lead to a significant increase in blood pressure and heart rate, and thus could lead to some serious side effects if not monitored closely. The same applies if an androgen increases or decreases MAO levels as this would require one to readjust the dosage.
Now, in reality, there isn't a large risk involved with these drugs and concurrent use of androgens, but caution is warranted and dosages should be adjusted accordingly if the patient finds that the drug or drugs aren't as effective as they were prior to androgen usage. (1-7)
