Supplementing progesterone and taking NPP

Xander24

Xander24

New member
My doctor has prescribed me micronised progesterone 10mg, pregnenolone 100mg, and DHEA 40mg as a part of my TRT regimine. I was about to do a blast for 14 weeks of NPP. Am I at a greater risk of side effects due to the 19-nor issues and progesterone? I keep E2 in check with aromasin, but just want to see if there is an added risk here?
 
Because I have low progesterone and progesterone is very important in men as well as women. Men with low test often have low progesterone, which has negative consequences like libido and ED issues. I believe if he is bringing my levels up to normal then it shouldn't put me at any more risk of prolactin related sides with NPP if I manage my E2. I've never had problems when running tren with prolactin related gyno, but just wanted some mod input of they have any.
 
I am taking HCG, 250iu Wednesday and Saturday. It' an extensive protocol I'm on. Was testosterone deficient, HGH Deficient, D3 Deficient, High E2, Low progesterone, I could go on and on. My doc is very good and very thorough. Knows I want to get my lady pregnant, so fertility and sex drive are big goals to strive for while keeping me in the high range of normal for a male 10 years younger than me. Progesterone plays a role here and he thinks it will improve libido, prostate health, and the ED I was experiencing.

He's a brain expert and on top of my endocrine health he specialises in brain health as well, so he is a big advocate of peptides, nootropics, Lithium, and all sort of vitamins and minerals I get concocted at a local compounding pharmacy.
 
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Megatron28 said:
That should suffice to keep everything in check. Maybe up the dose to 500iu twice a week?
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Just while blasting the NPP and Mast? then drop back down to 250iu 2x per week after the blast and just back on 165mg/ week of test e? At the end of the day I'm only blasting 400mg/week of NPP, I'd be surprised if prolactin reared it's ugly head on that dose, especially since it never did while running tren and allot more test. I'm keeping test at 165mg/week in this blast. Note that i edited my post above for more of an explanation of my protocol. And thank you for your reply.
 
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Xander24 said:
Just while blasting the NPP and Mast? then drop back down to 250iu 2x per week after the blast and just back on 165mg/ week of test e? Note that i edited my post above for more of an explanation of my protocol. And thank you for your reply.
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Sorry for not being clear. I would consider increasing the hCG dose permanently. Not just for the blast. That really should do the trick so that you don't need supplements.
 
Interesting. OK, Thank you. I'll do some homework and check it out. I need to read up on DHEA and pregnenolone along with Progesterone supplementation as they are all compounded into one dose. So I stop them all if I stop one. I will say I'm 6 weeks into TRT with this protocol. I feel amazing so far. As far as cognitive benefits go these peptides are just unreal. It's amazing what HGH can do, and you don't realise it until you get your brain pumping it again. Enjoying the nootropics as well, and course getting my test back is just starting to reap the benefits.
 
If that is the case, give the 250iu of hCG twice weekly more time to work. It should help.

Let me guess, you bought the supplements directly from your doctor? Probably on the expensive side?
 
Megatron28 said:
If that is the case, give the 250iu of hCG twice weekly more time to work. It should help.

Let me guess, you bought the supplements directly from your doctor? Probably on the expensive side?
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They are expensive, but he prescribed them and I had to go to the local compound pharmacy to have them made. I'm sure he gets his cut. He does have a deal with the other compound pharmacy that brews my peptides. He's doing well.

So do you forsee any issues with supplementing progesterone and blasting NPP if I mage my e2 with aromasin?
 
i think pregnenolone and DHEA are good to have in hrt, specially if you do not want to take HCG. but for this cycle i would not worry since what you are on is meant to just keep you are normal levels. have an AI though.
 
juced_porkchop said:
i think pregnenolone and DHEA are good to have in hrt, specially if you do not want to take HCG. but for this cycle i would not worry since what you are on is meant to just keep you are normal levels. have an AI though.
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Agreed, and thanks. I take Aromasin as part of my protocol, I think 12.5mg 2 to 3 times per weeks should be enough ofr 165mg/ week of test E and 400mg /week of NPP. Also blasting 600mg / week of masteron.
 
Megatron28 said:
I am just not convinced that the supplements will be necessary given that you are taking hCG.
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My plan is to run them until they are gone. Get the blood work, right in the middle of it, then run 12 weeks without them and compare blood work. The doc tests for Progesterone so we will be able to analyse each set of bloods to see where I am at. I'll stick to the 250iu with supps, and then in the second 12 weeks drop the Progesterone, DHEA, pregnenolone, and lithium (they are compounded) and up the HCG to 500. I do like the Lithium at 10mg / day. It's a great mood enhancer. So I wonder if the compounding pharmacy can just make me that not compounded with the other hormones. I've posted my entire protocol in the "My Steroid Cycle" Forum. it will be interesting to see where I eventually land.
 
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Xander24 said:
My plan is to run them until they are gone. Get the blood work, right in the middle of it, then run 12 weeks without them and compare blood work. The doc tests for Progesterone so we will be able to analyse each set of bloods to see where I am at. I'll stick to the 250iu with supps, and then in the second 12 weeks drop the Progesterone, DHEA, pregnenolone, and lithium (they are compounded) and up the HCG to 500. I do like the Lithium at 10mg / day. It's a great mood enhancer. So I wonder of the compounding pharmacy can just make me that not compounded with the other hormones. I've posted my entire protocol in the "My Cycle" Board. it will bei nteresting to see where I eventually land.
Click to expand...

I wouldn't change your hCG dose. Then you won't be comparing apples to apples.
 
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