My first quad injection was with test e and did the same. Swelling went down in a few days but the red went down to the knee and was very stiff. Injection protocol was on point, just think it to be virgin. Now most recently I had same issue in my delt. Been injecting in delts 2-3 times a week on last 2 cycles and I shifted a little over so wasn't to hit the same spot and it became swollen and red, eventually made its way to my outer biceps tried area. So I think it happens when the muscle is exposed to that particular oil for the first time.
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