Testosterone randomly went to zero, no reason at all

ironhorse123

New member
Hello everybody, I have been googling terms of "TRT in 20's" and this forum had many threads, i scrolled through some but found nothing like mine or with any answers to help. I know this is my first post but if anybody here has any knowledge or anything they can contribute I would be more than grateful.

I am a 21 year old male and my testosterone has randomly shut down. I have never touched any recreational drugs, performance enhancing drugs (including steroids of any form), cigarettes and I dont drink alcohol. I do exercise regularly and gym 5-6x a week.

Around 8-9 months back I started noticing loss of libido and I thought nothing of it. After a few weeks of noticing I had no sex-drive or intent to masturbate I decided I should really attempt to, as I know its healthy to ejaculate once in a while. I wasnt able to acquire a proper erection and even then during the climax no ejaculate came out at all. Over the last few months I have done it 3 times in total and no ejaculate came out in each attempt which led me to seek medical assistance.

I went to a local GP and he suggested I do a blood test which tested for my testosterone levels, thyroid and a few other random things. The results came back; (Im going to write down the main ones)
-Iron levels were fine-
-Testosterone : <0.3 nmol/L [8.3-29]-
-Free testosterone : 3.8 pmol/L [25.0-120.0]-
-Thryroid stimulating hormone : 1.2 mIU/L [0.5-4.5] {results consistent with euthyroidism}-

He told me my body has stopped producing testosterone and told me I should get an ultrasound of my testicles and adrenal glands (as they produce testosterone and if there is a tumour it could be effecting the production of testosterone). I got my ultrasound and the results showed :
-Liver is normal size
-Portal venous flow is in correct direction
-Spleen, pancreas and aorta appear within normal limits
-Both kidneys are normal size
IMPRESSION: No significant abnormalities are visualised. No adrenal mass is demonstrated.
FINDINGS: Both the right and left testis are normal in size a nd appearance with no focal lesion demonstrated. There is normal vascularity. No hydrocele or varicocoele.

On may last year, me and a few friends wanted to compare our testosterone levels against each other as a competition to see whose body produces more. So we did a blood test then . My test level was 9.3nmol/L with the range of [8.3-29]. So it;s even more of a shock that my testosterone levels randomly shut down when they were healthy (within normal levels) last year and there is no visible reasons as to why my body has stopped producing it.


I went back to the GP with the ultrasound results and then he wrote me a referral to go see an endocrinologist. He also told me to get another blood test done until I go see my endocrinologist. The second blood test results showed the exact same as the first one TEST level : (<0.3) .

Im keeping my parents updated with everything and after I told my mum about the ultrasound she insisted I get a second opinion and to go see our family GP. Just like the first GP, this one was also shocked at whats happening. He told me if the problem isnt related by a primary cause (problem from the actual testicles) that it has to be related to the brain. He suggested that the pituitary gland could be the reason why my testosterone has shut down and said that the endocrinologist would most likely then want to check my pituitary. To save time he told me to get a MRI scan of my brain before I visit the specialist to receive quicker treatment. The MRI results showed:
- The pituitary gland is of normal size and shows normal signal intensity. There is uniform enhancements with no masses seen. The pituitary stalk is in the midline. No suprasellar mass is demonstrated. No abnormalities are seen in the whole brain sequence.

I visited the endocrinologist and presented him all the blood tests, the ultrasound results and the MRI. He checked my blood pressure, checked my scrotum then ordered a blood test which would test for more specific hormones. He asked if I had taken steroids and I told him I havent and he booked me to come back in a few days when his blood test results come back. The results from his test:
-Tests 17 hydroxyprogresterone and Insulin growth factor 1 still are being examined and final report to follow.
-Thyroid stimulating hormone : 1.74 [0.35-5.50] mIU/L
-Cortisol - rndm : 269 nmol/L
-Testosterone : 0.6 nmol/L (8.0-30.0)
-DHEA Sulphate : 10.6 umol/L [3.7-10.2]
-FSH : <1 IU/L [1-8]
-LH : <1 IU/L [2-8]
-Prolactin : 7.2 ug/L [<20.0]

When I went back he examined the results then told me he is certain that Ive previously taken steroids . He said the pattern of results follow the same pattern as someone who has taken steroids;. I tried explaining to him that I have no reason to lie, he isnt the police nor my parents.. that if I had taken steroids I would tell him so he can fasten the process to start TREATMENT . I tried explaining to him that there is no logical reason why I would lie to him, why I would waste money and time doing all these different tests like the MRI if I knew myself the reason it has shut down is because of steroids. I told him my testicles were of normal size (according to the ultrasound) and that someone on steroids would have their testicles shrink in size and also asked him if he had checked my estrogen to make such an accusation. He then made a smart remark saying ; you seem to know a bit too much steroids;. I tried explaining going to the gym and researching the human body/nutrition is a hobby to me but he seems convinced otherwise. He told me he is going to speak to a few colleagues of his and for me to call him back the day after.

I called back the day after and he told me that he spoke to a few colleagues and they all agree with him that I must of taken steroids in order to be like this. I tried my hardest to keep calm and ignore his accusation and asked him to put aside his suspicion and to try follow up what;s happening. He wants to now test my Gonadotropic-releasing hormone [GnRH/LHRH]. This test would also have to be done at a hospital. I have limited knowledge but apparently they have to administer a drug and they check the relationship between what they inject and other hormone(s) to see what happens? But he told me that the drug they administer is hard to get and he needs to send a letter to get the drug approved then transported from another state to here.

Right now I am currently waiting for the drug to be approved and then book in a time with the hospital to test how my GnRH responds. I honestly have no reason why my testosterone has randomly shut down and have been attempting to research causes online but to find no answer. The reason im posting this is maybe someone on here has had a similar experience or knows of someone that has and may know what it could be. My friend says it could be genetic and could be something like [Adrenoleukodystrophy] .

If anyone has any idea on what it may be or could give any advice at all I would greatly appreciate it. Its honestly taking a toll on my normal life routine but I am trying my best to stay optimistic.
 
Last edited:
so the first thing i thought when i read this was pituitary myself.. possibly genetic or cancer? but that got ruled out...

then i thought it was secondary.. which is what it is.. your LH levels are WNL.. yet youre not producing test.. your testicles are not producing testosterone.. .

the logic that your doc is following is correct.. he cant help but assume youre on steroids because everything but your nut size indicates that..

youre a rare case.. so dont be mad at the doc.. the next test he is asking for is the next logical step.. wait for that
 
the best person to answer your question is rip... let me get him in here..
 
Have you ever taken any "testosterone boosters" or any pro hormones? I know you said no steroids but some people don't consider pro hormones as steroids when in fact they are and there are alot of "Test Boosters" that are actually steroids as well.

Like 3J said I wouldn't get mad at your doctor even though it is hard not too,that is one of my pet peeves when someone accuses me of something I didnt do and then basically calls me a liar.
 
Interesting.

Your doc is right to be suspicious, test doesnt suddenly crash over a year without some sort of external influence.

Since last year, have you made any dietary changes at all?
Have you used any legal supplements - preworkout drinks, prohormones, vitamins, anything at all?
Has your weight flunctuated at all over the last year? Any rapid increase/decrease could be a sign of an infection or other serious conditions.
Any newly introduced medications?
 
Last edited:
Has to be something that you are taking or are exposed to. Does anyone you have physics contact with use testosterone gel/creams?
 
I'm willing to bet you took a supplement with a pro hormone in it.

Well your LH a Fsh are low. The end result should be treat meant with HCG and Clomid. Standard Post cycle therapy. You may need it for life.

MAybe igf1-lr3. It will reverse most atrophy.
 
Have you ever taken any "testosterone boosters" or any pro hormones? I know you said no steroids but some people don't consider pro hormones as steroids when in fact they are and there are alot of "Test Boosters" that are actually steroids as well.

Like 3J said I wouldn't get mad at your doctor even though it is hard not too,that is one of my pet peeves when someone accuses me of something I didnt do and then basically calls me a liar.

I have never touched any prohormones or peptides. Although I did take tribulus tablets around 2 years ago only for a few days and that was for the sex drive boost thing to try it out. That blood test i did in May after showed my levels were somewhat normal so i dont think that had an effect on it. Other than that ive taken a viagra tablet once just for experimenting and i told that to the specialist and he said that wouldnt be the cause.

Interesting.

Your doc is right to be suspicious, test doesnt suddenly crash over a year without some sort of external influence.

Since last year, have you made any dietary changes at all?
Have you used any legal supplements - preworkout drinks, prohormones, vitamins, anything at all?
Has your weight flunctuated at all over the last year? Any rapid increase/decrease could be a sign of an infection or other serious conditions.
Any newly introduced medications?

No pre workouts at all, although alot of sugarfree redbull. ALL the supplements i was taking were : Swiss multivitamin , Fish oil 6g a day, Extend BCAA, CLA , Carnitine , EGCG and my protein. (ALL supplements were taken at the recommended dosage on bottle and never more).
My weight and training is one thing i definitely changed. I started training 6-7 days a week, training twice on some days and was doing HIIT twice a week with LISS once a week. My diet was reasonably on point with 260g protein everyday. Carbs were 450g on my high carb days, 400g on mid carb days and 350g on my low carb days and each week i dropped carbs by around 40g from all my days and boosted fats by a few g to compensate . My fats were around 50g on high carb day, 60g on mid carb day and 70g on low carb day (im estimating my fats now but that was around it, it was catered to suit my carb intake and overall calories)
I noted my bodys strength went up, i felt better than ever as i was filling my macros with dense food sources and hence felt really healthy. I dropped from around 94kg to 83kg over the course of 9-10 months and then after i slowly noticing the loss of libido and eventually it lead to having no sex drive and no semen coming out of my penis which then i went to a GP.

Has to be something that you are taking or are exposed to. Does anyone you have physics contact with use testosterone gel/creams?

Not that I know of.

I'm willing to bet you took a supplement with a pro hormone in it.

Well your LH a Fsh are low. The end result should be treat meant with HCG and Clomid. Standard Post cycle therapy. You may need it for life.

MAybe igf1-lr3. It will reverse most atrophy.

I honestly never did. Look, if i honestly were to take anything and that led to this why would i go about doing all these tests to find out whats wrong. I would simply tell the doctor himself and he can assist with treatment. He has to keep everything confidential. There is not one single reason why i would need or want to be lying. When you say end treatment would be HCG and clomid, would the purpose of that be to bring back my testosterone levels?

I appreciate everyone contributing and taking the time to reply. It really means alot, thanks alot. Im hoping that someone may know any other reasons as to why it happened or a solution or anything really, thanks again guys !
 
For you to have gone from 94-83kg in 9-10 months suggests you were in a caloric deficit for that whole period, can you confirm this?
Training 6-7 days per week, along with hiit 2x week, is conplete overkill & does suggest overtraining especially when combined with a caloric deficit for the entire time.

A caloric deficit through your diet + high level of activity is never a good idea for naturals, especially if you kept up this pace for 9-10 months straight.
Its not uncommon to see weird things happen to your endocrine system when this sort of programme is prolonged for a long time. Test, cortisol, thyroid, among others, all tend to mess up because your body is convinced your starving & trying to become as efficient as possible by shutting down everything to keep up with your high level of activity.
To keep it simple: cortisol gets elevated leading to leptin resistance in the brain = terrible things to your metabolism including test/thyroid/etc shutdown. The fact that you were feeling good then all of a sudden a bunch of symptoms started appearing rapidy is a good sign of this exact process occuring.

Does your doc know you were running a caloric deficit for months with no break? Is he aware of your high frequency training schedule?
Based on the info you provided, this is the only cause that makes sense. I suggest you stop training for a few weeks (yes, completely) & increase your calories to maintenance to see if it makes a difference.
You will need to stay at maintenance for at least 4-6 weeks but you can reintroduce the training a few weeks in if you start to feel better.

This may not be the only thing going on, but at least if you follow this solution we can rule out diet & training as causes.
 
Last edited:
For you to have gone from 94-83kg in 9-10 months suggests you were in a caloric deficit for that whole period, can you confirm this?
Training 6-7 days per week, along with hiit 2x week, is conplete overkill & does suggest overtraining especially when combined with a caloric deficit for the entire time.

A caloric deficit through your diet + high level of activity is never a good idea for naturals, especially if you kept up this pace for 9-10 months straight.
Its not uncommon to see weird things happen to your endocrine system when this sort of programme is prolonged for a long time. Test, cortisol, thyroid, among others, all tend to mess up because your body is convinced your starving & trying to become as efficient as possible by shutting down everything to keep up with your high level of activity.
To keep it simple: cortisol gets elevated leading to leptin resistance in the brain = terrible things to your metabolism including test/thyroid/etc shutdown. The fact that you were feeling good then all of a sudden a bunch of symptoms started appearing rapidy is a good sign of this exact process occuring.

Does your doc know you were running a caloric deficit for months with no break? Is he aware of your high frequency training schedule?
Based on the info you provided, this is the only cause that makes sense. I suggest you stop training for a few weeks (yes, completely) & increase your calories to maintenance to see if it makes a difference.
You will need to stay at maintenance for at least 4-6 weeks but you can reintroduce the training a few weeks in if you start to feel better.

This may not be the only thing going on, but at least if you follow this solution we can rule out diet & training as causes.

I didnt really go in depth with my training regime and my dieting but i would definitely let him know. Yes I guess you can say i was in a deficit for the whole period and my training was over the top.
When i say 6-7 times a week it was mostly 7 days a week and i would take a day off once every 2-3 weeks, and on those 7 days that i trained i doubled trained on 2-3 of them. Then 2x HIIT hillsprints a week along with low-intensity steady state swimming once a week.
I forgot to mention aswell towards the last month of my dieting and training i did complete ketosis, i was having having <40g carbs a day, keeping protein and fats high with one carb up a week at 300g carbs. maybe that also had an effect ?
The reason I was really motivated was because i went through a severe break up with my ex-girlfriend back then and was just very driven. All the exercising was a good outlet to forget about her and it really did help to move on.
 
Last edited:
There is a syndrome being associated with cross fit training where the body shuts down from over training. Look into that.

I looked it up, came across this article "breakingmuscle.com/strength-conditioning/overtraining-can-kill-you-the-3-stages-of-overtraining-part-2"

The guys testosterone level on that site went to zero aswell. I guess there is a link between over training and shutting down testosterone. Hopefully there are solutions on how to reverse these effects aswell
 
The "solution" is to stop training and to increase your calories to maintenance for a sustained period of time - basically the reverse of what caused this situation.

It has nothing to do with macros per se, your overall energy intake (calories) were too low for too long & your activity leevel was too high for too long - combined you end up with the position your in now.

It will take a few months before you see noticeable improvements through bloodwork, but this really is the best solution without putting you on medication for life (trt, etc).
 
The "solution" is to stop training and to increase your calories to maintenance for a sustained period of time - basically the reverse of what caused this situation.

It has nothing to do with macros per se, your overall energy intake (calories) were too low for too long & your activity leevel was too high for too long - combined you end up with the position your in now.

It will take a few months before you see noticeable improvements through bloodwork, but this really is the best solution without putting you on medication for life (trt, etc).

Theoretically speaking if i were to be put on TRT and then stopped after a while would my natural levels ever be 'kickstarted' ?, or is it once you start TRT its for life?
Thanks again for the constant contribution, means alot :)
 
Based on the scientific evidence available - it would be highly unlikely & even if your natural levels did restart, it certainly wouldnt be at the level that you were at previously, which is not good for someone at your age.

This is why I recommend naturally solving the problem through higher calories/less activity, these sort of hormononal adaptations are not uncommon for guys who diet for too long/overtrain & can be fixed.
IMO, going on something like trt for something like this is not the right solution long term & can be completely avoided.
 
Based on the scientific evidence available - it would be highly unlikely & even if your natural levels did restart, it certainly wouldnt be at the level that you were at previously, which is not good for someone at your age.

This is why I recommend naturally solving the problem through higher calories/less activity, these sort of hormononal adaptations are not uncommon for guys who diet for too long/overtrain & can be fixed.
IMO, going on something like trt for something like this is not the right solution long term & can be completely avoided.

After reading a few online articles including "bodybuilding.com/fun/berardi22.htm"
which states in one part "However, once this system "burns out", the sympathetic nervous system decreases in activity and the parasympathetic system dominates. As a result, overtrained endurance athletes can expect the outcomes listed by Kraemer and Fry.

Decreased total testosterone levels
Decreased total testosterone/cortisol ratio
Decreased free testosterone/cortisol ratio
Decreased total testosterone/SHBG (sex-hormone binding globulin) ratio
Altered cortisol levels
Decreased sympathetic tone
Decreased nocturnal and resting catecholamines
Increased sympathetic stress response
Increased creatine kinase
Decreased exercise-induced lactate"

I guess it is safe to conclude that my overtraining and diet was the cause of this. I just need to do more research to see what would the best and most effective way to a total recovery be
 
so the first thing i thought when i read this was pituitary myself.. possibly genetic or cancer? but that got ruled out...

then i thought it was secondary.. which is what it is.. your LH levels are WNL.. yet youre not producing test.. your testicles are not producing testosterone.. .

the logic that your doc is following is correct.. he cant help but assume youre on steroids because everything but your nut size indicates that..

youre a rare case.. so dont be mad at the doc.. the next test he is asking for is the next logical step.. wait for that
Totally agree..

OP i wish you the best!

if they say to go on hrt, i would rec a few months of Clomid therapy before committing to life long hrt shots.
 
Back
Top