For a first time tren user, I STRONGLY recommend using tren ace to see how you respond to tren. Some folks have a time with the sides and it would be beneficial to find that out when you can drop it and clear in three days instead of two weeks.
As for your dose, many people do fine on low dose tren. I found that with tren ace, I can see nice results at 60mg ed. I prefer about 80mg ED now after having run it quite a few times now. I have tried it as high as 150ED (as a kickstart)and I'll drop tren before I do that again. It sucked pretty bad. So I have experimented with it and found the doses that I like best from a gains/sides perspective.
While there is less tren hormone per 100mg (due to ester weight), I still started my tren e at 60mg ED. I prefer to inject everything EOD or ED. I seem to have much less sides with all compounds. With test e and tren, you will have much more stable blood levels if you inject E3.5D instead of once a week. Once a week is too much of a stretch for sure. Since we are talking about sides, they can be controlled much better by keeping blood levels stable.
Hope this helps.