I read the kind of posts people make and it really surprises me that people give this medical advice with such boldness and confidence when they most likely don't have any medical background (I'm not talking "my momma's momma is a nurse blah blah blah) anyway, A) if you have an abscess, it does not ALWAYS have to be drained as someone earlier said... B) YES antibiotics will "reach it" if it is a smaller abscess without having to be drained. C) the type of antibiotic will depend on what type of infection it is, but the most commonly prescribed broad spectrum antibiotic for abscess is Bactrim-DS at my ER-we see about 10/day on a normal shift.