jack3d4life
Slave to the needle
Aromasin or adex? I swear adex has little to no effect of me unless the dose is retardedly high.
Which AI do you guys prefer??
- Thread starter jack3d4life
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jack3d4life
Slave to the needle
For sure. I'm about to switch dudes. I'm super e2 sensitive in only my damn left nipple. Stupid thing gets so puffy no matter how much test im running. I'm only pinning 250 a week and I'm at .5mg eod of adex that doesn't help at all
Rida5d
city of the sun
Did u have some blood work?
Puffy nipples isn't an indication always ur E is high.
jack3d4life
Slave to the needle
Insurance is currently switching over but I will have them done again. I've had them done in the past and that's what it has always been.
LetsGoHeavyBro
New member
Liquidex.. Works perfect for me, helps with bloat and other sides..
Test Rage
Skinny Mon
I found this when I was searching for my choice of AI:
"Arimidex is not a good aromatase inhibitor for men. Stick with aromasin. Arimidex is a weak inhibitor of E2(it's strength is inhibiting E1 in women. Not well suited for men). It's also a competitive inhibitor (not a suicide inhibitor) so you'll get a rebound when you come off or need a higher dose. Aromasin is a much better solution. It binds to the aromatase and kills it. So there is no rebound and stops more E2 production.
Arimidex is a competitive inhibitor so it competes for the binding site of the enzyme with testosterone and blocks it from getting converted to estrogen. It's not very good at it, but that's what it does. So the enzyme is still present in large numbers because your body overcompensates. When you stop the Arimidex the blockade is gone and the E2 levels soar. That is why suicide inhibitors like aromasin are preferred.
When it comes to this comparison its more about type of estrogen suppression as opposed to "strength". Arimidex is a VERY potent sulfatase inhibitor, which inhibits estrone. It is a moderately strong aromatase inhibitor (weak as compared to aromasin, AIFM or letrozole). This is fine for women with breast cancer who produce percentage wise very high levels of estrone (the weak estrogen), which can be converted to estradiol (the strong estrogen) via aromatase.
For men this is generally not very good, especially for men on TRT since sulfatase inhibitors have very little effect on exogenous testosterone. Actually its generally not a good thing since it nearly completely eliminates estrone, while still allowing estradiol. If you have a choice as a man, you want estrone (weak estrogen) with near total elimination of estradiol (strong). AIFM and aromasin do inhibit sulfatase, though to a lesser extent than the competitive inhibitors (dex and letro). They are both potent aromatase inhibitors and highly suppress estradiol. Since exogenous test converts to estradiol via aromatase, AIFM and aromasin are much better suited.
Lowest doses of letrozole completely suppresses glandular production of estrone(E1). while it generally takes higher end doses of exemestane (aromasin) to come close to doing this. Exemestane dose dependantly decreases estradiol and to a lesser extent estrone. Basically aromasin at low doses is mostly peripheral, which means blocking conversion of estrone, testosterone and other aromatic precursors to estradiol. Whereas because they are competitive inhibitors that have high permeability through tissue types, arimidex and letrozole have high affinity and saturation of tissues like testes and adrenals, where estrone is produced. They highly block synthesis of aromatase in those tissues at even lowest doses."
I am going to go with aromasin. But I will have one of the others on hand to experiment should aromasin be failing me, was bunk aromasin, or for experimentation.
"Arimidex is not a good aromatase inhibitor for men. Stick with aromasin. Arimidex is a weak inhibitor of E2(it's strength is inhibiting E1 in women. Not well suited for men). It's also a competitive inhibitor (not a suicide inhibitor) so you'll get a rebound when you come off or need a higher dose. Aromasin is a much better solution. It binds to the aromatase and kills it. So there is no rebound and stops more E2 production.
Arimidex is a competitive inhibitor so it competes for the binding site of the enzyme with testosterone and blocks it from getting converted to estrogen. It's not very good at it, but that's what it does. So the enzyme is still present in large numbers because your body overcompensates. When you stop the Arimidex the blockade is gone and the E2 levels soar. That is why suicide inhibitors like aromasin are preferred.
When it comes to this comparison its more about type of estrogen suppression as opposed to "strength". Arimidex is a VERY potent sulfatase inhibitor, which inhibits estrone. It is a moderately strong aromatase inhibitor (weak as compared to aromasin, AIFM or letrozole). This is fine for women with breast cancer who produce percentage wise very high levels of estrone (the weak estrogen), which can be converted to estradiol (the strong estrogen) via aromatase.
For men this is generally not very good, especially for men on TRT since sulfatase inhibitors have very little effect on exogenous testosterone. Actually its generally not a good thing since it nearly completely eliminates estrone, while still allowing estradiol. If you have a choice as a man, you want estrone (weak estrogen) with near total elimination of estradiol (strong). AIFM and aromasin do inhibit sulfatase, though to a lesser extent than the competitive inhibitors (dex and letro). They are both potent aromatase inhibitors and highly suppress estradiol. Since exogenous test converts to estradiol via aromatase, AIFM and aromasin are much better suited.
Lowest doses of letrozole completely suppresses glandular production of estrone(E1). while it generally takes higher end doses of exemestane (aromasin) to come close to doing this. Exemestane dose dependantly decreases estradiol and to a lesser extent estrone. Basically aromasin at low doses is mostly peripheral, which means blocking conversion of estrone, testosterone and other aromatic precursors to estradiol. Whereas because they are competitive inhibitors that have high permeability through tissue types, arimidex and letrozole have high affinity and saturation of tissues like testes and adrenals, where estrone is produced. They highly block synthesis of aromatase in those tissues at even lowest doses."
I am going to go with aromasin. But I will have one of the others on hand to experiment should aromasin be failing me, was bunk aromasin, or for experimentation.
jack3d4life
Slave to the needle
Adex
aromasin is too expensive
Time to find a new source bro haha.
jack3d4life
Slave to the needle
No shit bro? Well I'm gonna switch over to aromasin and if the puff continues then fuck it that's the way it is haha
Metalhead
New member
Haha yeah. They suck and there are few different reasons why but they happen less for me when I use aro. I run it at 12.5mg ed split every 12 hours keeps me at 14.4pg/ml when running 200mg of test a week
jack3d4life
Slave to the needle
Good shit bro I'm gonna hit up my dude today for some aro and some nolva. Running low on the shit.
Adex + proviron. I used to also have to take high doses of AI. on my last 500mg test / wk cycle I was taking 1mg ED of Adex and still on the high end E2 in 40's. Now this time I'm again on 500mg/wk and I was taking .4 mg Adex 2x a week on my last blood test my E2 was a 6. Thankfully I don't experience any sides with a low E2 Not sure how long it's been that low did my first blood test on this cycle a couple months in, I stopped taking the AI for now might start it back up at .2 a week. Since the proviron is what makes the AI work so good, proviron itself isn't a substitute for AI.
Sorry but whatever that is you posted isn't accurate. Far from it to be honest.
In my experience, these options are not mutually exclusive. I keep a few of these compounds around for various reasons. Letro is an E2 destroyer, but it will knock your pud in the mud. That said, you may find yourself in a bad situation and you could need that level of effectiveness. I like to let my E2 roam a bit, as it helps my strength, but when I find myself watching terms of endearment--it is time to pull out the tools.
I keep letro, aromasin, raloxifene, nolva, and proviron on hand at any given time. It is probably a bit of an overkill, but it is estrogen management, not estrogen damage control.
I keep letro, aromasin, raloxifene, nolva, and proviron on hand at any given time. It is probably a bit of an overkill, but it is estrogen management, not estrogen damage control.
Norsegod
Gym=My Drug
Damn dre, I didn't even bother reading that earlier as I was at work and sneaking into the forum(I just missed you guys so) but thanks for pointing that out. Test rage, he's right. Idk where you got that, but it is quite inaccurate. Be careful where you get your info and always check 3-4 didn't places when researching one topic to be sure. The net is full of straight bs
riprockwell
New member
I like Stane over Adex. Adex always trashed my liver values. That's something I noticed about it. I feel better on Stane.
