1 year into TRT, not pleased with recent lab work, please advise.

[xplicid]

Hey Guys,

Ive been on TRT for 1 year with fairly good success. quick background: 29 year old male, 195lbs @ 10%bf. 135mg of test cyp split into mon and thurs injections. anxiety/depression down, libido and erections improved, however, still low energy and fatigued. I have a much better than most doc, fairly educated on the matter and willing to listen to what i have to say.

Ive dealt with erratic E (ranging from 50pg/ml - 75pg/ml) from the onset of TRT and have tried numerous things. started at once weekly at 150mg per week and reduced to 135mg done twice per week. Then when E was still too high, dropped HCG all together. Still too high, doc suggested Iron... Still too high, doc suggest DIM. Well after all this, E is still high, lab work below (done Mid May):

TESTOSTERONE, TOTAL, LC/MS/MS 744 250-1100 ng/dL
TESTOSTERONE, FREE 164.6 46.0-224.0 pg/mL
TESTOSTERONE,BIOAVAILABLE 324.3 110.0-575.0 ng/dL
SEX HORMONE BINDING GLOBULIN 20 10-50 nmol/L
ESTRADIOL 74 H < OR = 39 pg/mL

I dont have any signs of gyno what so ever, my sex drive is healthy along with good erections; I dont have any prostate problems and i havent gained any weight.. I do sweat excessively, very mild edema if standing but i do feel weak and lethargic in the gym

The time has come where i think it evident i need to start using an AI. Ive done a ton of research and it varies SOOO widely (understandably what works for someone may not work for another). People also tend to be pretty nonchalant about it, carelessly taking and suggesting WAY to much AI. the prevailing consensus tends to be .25mg Anastrozole on shot days. my doc only deals with exemestane and i can seem to find a consensus on that. some take 12.5mg daily, others 6.25mg twice a week. I totally understand everyone is different but bearing in mind my situation, what suggestions do you guys have for me?

 

[Dreaded Pirate Roberts]

Isa isa given to address your estrogen but you need to take baby steps. I crashed my estrogen and my hips started being arthritic. It took month for the estrogen levels to normalize.

 

[IMT staff]

135 mg twice per week and your TT is only 700?

Just want to make sure because it seems a little low.

Your not gonna need much anastrozole to bring it down under 50, like 0.25mg per week and thats all you really have to do.

Hope this helps

 

[halfwit]

135 mg twice per week and your TT is only 700?

Just want to make sure because it seems a little low.

Your not gonna need much anastrozole to bring it down under 50, like 0.25mg per week and thats all you really have to do.

Hope this helps

Damn, that's more than I take. I agree, although if only exemestane is available, I think you'd agree with 6.25mg EOD. Should be ED for the half-life in men, but I'd rather be on the cautious side than be too aggressive.

 

[cbburrr]

135mg of test cyp split into mon and thurs injections.

I think that is his weekly total.

I take 1/4 mg of adex once per week on a 200mg cruise dose. keeps E2 in the mid 20's most of the time.

 

[xplicid]

135 mg twice per week and your TT is only 700?

Just want to make sure because it seems a little low.

Your not gonna need much anastrozole to bring it down under 50, like 0.25mg per week and thats all you really have to do.

Hope this helps

Its 135mg total, i split that to 67.5mg monday and 67.5mg on thursday. labs were done during a trough, its normally around 1000 TT.

Ive read its best to keep it under 30? do you think .25mg during injection days, twice weekly, would accomplish this?

 

[THE-DET-OAK]

Under 50 is fine on a non sensitive. Either way I start low and go slow.

 

[Dreaded Pirate Roberts]

29 feels good to me.