my lab rat has used RUI exclusively now for a while. He has used clomid, nolva, arimidex, prami, and needles and syringes. So far, awesome products. as a matter of fact, after my lab rat had a dip of natty test due to synthetic hormones administered, he went through a clomid/nolva treatment and his test is now 897 two months after treatment. This is much higher than his 610 he had before the being administered synthetic hormones. Hope that helps.