Aromasiin/Exemestane dose for TRT

[THE-DET-OAK]

here is the problem, there is where backing your studies backing up your statements with studies, or b not believing anything that doesn't have a study done in the last year with exact parameters can get you ini trouble.

Just because something is 20 years doesn't mean anything has changed. The medical field thought testosterone gave you prostate cancer for 70 years.

Lipschultz has a lot of recent info, and his style of treatment is the most common one your gonna see around here, he is one of the best docs in TRT, and i doubt his opinion has changed much.

if you don't like one of the best TRT docs in the world's word for it, and the countless programs I've witnessed, here is something from AACE in 2006

Gonadotropin Therapy in Androgen Deficiency
It is known that hCG binds to Leydig cell LH receptors
and stimulates the production of testosterone.
Peripubertal boys with hypogonadotropic hypogonadism
and delayed puberty can be treated with hCG instead of
testosterone to induce pubertal development. The initial
regimen of hCG is usually 1,000 to 2,000 IU administered
intramuscularly two to three times a week (65). The clinical
response is monitored, and testosterone levels are measured
about every 2 to 3 months. Dosage adjustments of
hCG may be needed to determine an optimal schedule.
Increasing doses of hCG may reduce testicular stimulation
by down-regulating the end-organ; thus, a more optimal
result may occur with less frequent or reduced dosing. The
half-life of hCG is long.
The advantages of hCG over testosterone in this setting
include the stimulation of testicular growth, which
may be an important issue for some men. Use of hCG may
also yield greater stability of testosterone levels and fewer
fluctuations in hypogonadal symptoms (66). In addition,
hCG treatment is necessary for stimulating enough intratesticular
testosterone to allow the initiation of spermatogenesis.
The disadvantages of hCG include the need for
more frequent injections and the greater cost.

https://www.aace.com/files/hypo-gonadism.pdf

wat wat

dropping bombs

 

[LtDunbar]

here is the problem, there is where backing your studies backing up your statements with studies, or b not believing anything that doesn't have a study done in the last year with exact parameters can get you ini trouble.

Studies were asked for only after some discussioin. I was more interested in tangible facts. My purpose was to read something that I COULD believe. Opinions based on personal experience are invaluable also and should never be discounted. But it should be made clear if a statements is an opinion or not. Wouldn't you agree that any person ought to be questioned if they cannot substantiate their claims - no matter who they are?

Just because something is 20 years doesn't mean anything has changed. The medical field thought testosterone gave you prostate cancer for 70 years.
True. But chances are that a very great deal HAS changed in 20 years. That's why new science textbooks are printed rather often and breakthrough journal articles documenting research are constantly published.

Lipschultz has a lot of recent info, and his style of treatment is the most common one your gonna see around here, he is one of the best docs in TRT, and i doubt his opinion has changed much.

if you don't like one of the best TRT docs in the world's word for it, and the countless programs I've witnessed, here is something from AACE in 2006. Don't know Lipshultz so I have no opinion of him at this time. However, I do have a hope to respect his work and his findings and hope they can add to my knowledge.



https://aace.com/files/hypo-gonadism.pdf

wat wat

dropping bombs

In BOLD.

Thanks for the PDF. Slightly confused about the photo and its purpose though.

 

[THE-DET-OAK]

In BOLD.

Thanks for the PDF. Slightly confused about the photo and its purpose though.

This is what I mean! nothing changes with HCG its still the same as it was long ago! Not to mention there are very few studies on this exact discussion! There are a ton on rats but i don't use those for sources.

I have cited 2 references and speaking from my experience and others, with lab work to back it up, thousands. I could very simply use the data that is there to prove you wrong a third time but frankly i don't have time nor do I care too!

lol use your HCG 100 ed i could cares less, but your wasting it!

last words

down regulation

your in la la land.

The picture was fun because your arguing with yet your new to this, some people just don't wanna listen.

Where is your proof that down regulation does not exist?

Your missing the part about the refractory period. this is very basic, just like stimulating the pituitary with peptides that attenuate SS. The body is always and has been cyclical since the beginning of time.

This is a joke.

 

[LtDunbar]

It seems you don't like to be questioned. It's common knowledge that forums are for learning, debate, and an exchange of ideas. Whether a person has ten posts or ten thousand posts - like yourself - I would think he has the responsibility to listen and to answer with patience and good will. IMO, that is what a useful, productive member of a forum would do. The only purpose mocking and dismissal serves is to lessen the respect of others who are witness to it. I am a new member to this forum but by no means new to TRT or to scientific research. And admittedly, I have much to learn - as we all do - including yourself. As a professional educator, I want my students to question me just as I would question information before I present it to them. We are not sheep to be fed information, believe and to digest it just because we hear it or because it comes from a person with a title in front of their name. How many doctors have we found to be incompetent dolts? We must always question. I would suggest you get used to it. And I would also suggest you put your ego aside. It's very unattractive.

 

[Daniel_IMT_Staff]

Hello,

As Megatron has pointed out why do you want to lower you e2? I saw your response that you don't feel right, can you explain this further and has somebody evaluated that the e2 is the direct cause to this? Many times people experiment on their own and it most often isn't for the best. Why not have a great starting point and individualize your TRT after noticing adverse side effects and contributing it to a certain part of your TRT regimen?

Either way, I think Megatron was spot on with his advice and you are ignoring it. DIM in your opinion is garbage, but Megatron maybe has seen many people in your situation benefit from it which is why he advised it. I think his experience should be considered before yours.

THE-DET-OAK is trying to help you as well and I second everything he has said. I don't know but it seems like nobody here can help you as you don't wish to be helped! To answer your question on the dosage to start off on with the exemestane, do as you please! The dose is individual either way and labs will be your answer to what dose to use.

Good luck!

 

[LtDunbar]

Hello,

As Megatron has pointed out why do you want to lower you e2? I saw your response that you don't feel right, can you explain this further and has somebody evaluated that the e2 is the direct cause to this? Many times people experiment on their own and it most often isn't for the best. Why not have a great starting point and individualize your TRT after noticing adverse side effects and contributing it to a certain part of your TRT regimen?

Either way, I think Megatron was spot on with his advice and you are ignoring it. DIM in your opinion is garbage, but Megatron maybe has seen many people in your situation benefit from it which is why he advised it. I think his experience should be considered before yours.

THE-DET-OAK is trying to help you as well and I second everything he has said. I don't know but it seems like nobody here can help you as you don't wish to be helped! To answer your question on the dosage to start off on with the exemestane, do as you please! The dose is individual either way and labs will be your answer to what dose to use.

Good luck!

Daniel,
Thank you for your reply. I agree. The suggestions of Megatron were very useful - as were those of Soybean and Former Fatty. I'm grateful for them. I've benefitted too from those of THE-DET-OAK.

To answer your questions about E2: After being on TRT for a few years, you start paying attention to the signals your body is giving you. And I know when my E2 is affecting me - particularly as it relates to libido and energy. As I indicated previously, I believe I'm on a fairly conservative protocol. And I realize the goal of all of us on TRT is to eliminate the use of an AI. I've been trying to do that but I haven't had the success I would have liked. My E2 hovers in the high 30's to low 40's (On Quest's Ref. Range: <OR=29) and I'm very sensitive to it - as I also described.

I'm very active on other forums and I've paid great attention to the discussions on this matter of E2 control and I do have some knowledge of it. One thing I've tried is to lower my T dose and hCG dose - the goal to lower my E2. This probably helped. I've settled into the protocol I described in post #3 and I'm very comfortable with it and feel this is where I'll remain.

I thank Megatron for his encouragement regarding DIM. I respect his suggestion. I tried it for two months, as I said, but experienced no great strides in lowering E2 - still at 39. So that's the reason I began this thread. Needed to hear about Aromasin dosing. That's it.

I don't agree with your statement that I don't wish to be helped. If you read my posts again, you'll clearly see there is no evidence indicating that. I've listened, and gratefully commented on the posts of those who were generous enough to comment. The only thing I took issue with was a comment by THE-DET-OAK about hCG. There's no need to repeat why because it's all here.

So thank you again for your reply. As a whole I respect it. And thank you for your good wishes too.

 

[Daniel_IMT_Staff]

Hello!

Ok, I understand that but how do you deduce it is too high and needs to be lowered. It makes it seem like it has been good at one time and then my question would be what was your TRT protocol when it was lower or you felt better?

 

[Megatron28]

How about switching from one injection per week to two injections per week as I suggested earlier? In my experience it makes a huge difference from an estradiol standpoint. I don't remember my exact numbers, but when I pinned 100mg once a week my E2 was close to 100pg/ml two days after I pinned and in the 30's on the day I inject (before injection).

When I went to 50mg injections every 3.5 days my E2 was right around 30. A lot of other guys here have had similar experiences. For the record, I was not using HCG, but I still thing it could help you.

 

[LtDunbar]

Hello!

Ok, I understand that but how do you deduce it is too high and needs to be lowered. It makes it seem like it has been good at one time and then my question would be what was your TRT protocol when it was lower or you felt better?

I'd have to go back to when I began - on the patch. Responded within days but developed skin sensitivity. My urologist suggested I try pellets. I responded so well I felt like wanking off all the time! Not comfortable at all! Was happy that 4 pellets came out and I calmed down. Then went on Androgel and also responded well. I really liked the gel. Good energy, libido and erections. But then things changed. Needed more pumps to feel the effects and I started getting tired a lot. I started low dose Adex and felt immediately better. Kept my E2 in the mid 20s. But gels got VERY expensive - $175 co-pay/month.

Went to another doctor and started on shots (I only pay for my T) and continued on low dose adex. My E2 remained in the mid 20s. Adex kept me satisfactorily libidinous but it was hard to pin down the right dose and I hated the rebound while I was searching. Things happened so fast on adex that sometimes i didn't know if it was high E2 or low. Stopped adex and started DIM and I'm not impressed with DIM's effects. Tried Aromasin and I liked it immediately and energy and libido returned immediately. Only took 3 doses so far; 6.25mg EOD. And funny thing - I purposely skipped a couple of doses and substituted 200mg DIM/day and I'm in good shape. Apparently DIM is having some effect in E2 control in conjunction with Aromasin. Hard to figure out.

Did I answer your question?

 

[LtDunbar]

How about switching from one injection per week to two injections per week as I suggested earlier? In my experience it makes a huge difference from an estradiol standpoint. I don't remember my exact numbers, but when I pinned 100mg once a week my E2 was close to 100pg/ml two days after I pinned and in the 30's on the day I inject (before injection).

When I went to 50mg injections every 3.5 days my E2 was right around 30. A lot of other guys here have had similar experiences. For the record, I was not using HCG, but I still thing it could help you.

I am pinning SQ at 28mg EOD - so I'm pretty frequent (averaging 98mg/week). That along with 250iu hCG 2x week. I guess I should be grateful that I'm only at 39 but this number is too high for true comfort for me.

 

[Megatron28]

I am pinning SQ at 28mg EOD - so I'm pretty frequent (averaging 98mg/week). That along with 250iu hCG 2x week. I guess I should be grateful that I'm only at 39 but this number is too high for true comfort for me.

Sorry... I missed that when you posted it earlier.

 

[Soybean70]

I'm very curious about the answer to this question. I'm on 100mg/week Test Cyp and 250iu hCG/ 2x week.(Might bump it up to 3x week. My E2 is at 39. Reference range: <OR=29. Libido has been weak along with poor night and morning erections.

What's a good starting dose for Exemestane/Aromasin on TRT? I'm thinking 6.25mg ED. Too much?

6.25 mg at bedtime for me. It helps you sleep. I wouldn't take it during the day. When you're at the correct dose your libido will increase. I prefer aromasin over adex because aromasin won't hurt your libido unless you take too much

 

[Megatron28]

I have never heard anyone say before that taking aromasin at night helps them sleep. Just wondering if anyone else experiences this?