Deca Dick

[Bullseye Forever]

If you haven't done the L-Arginine before start out slow and move up to full dosing, it gives some people wicked stomach cramps and the shits!

oh yea i know lol,ive been using it for a long time,it helps with ED

 

[KaiserSose]

update on the problem ,,pretty much chalked it up to high estro as his nips started getting pretty sensitive,,a few weeks into the aromasin and nips feel way better but he said he had the problem again and just isnt getting those good test boners we all love,,libido is its just boners are 80% so basically problem still their ,, so i am thinking could this have turned into a prolactin issue i mean if his estro was too high for too long we all know that leads to prolactin problems when running a 19 nor ,,so could it be that estro has gone down but prolactin remains high ? but wont high prolactin kill libido not just boners

 

[Natehayes]

I had good luck with prami when I was running deca.

Not an expert but I though prolactin issues can give you bad boners but still leave you with normal libido.

Tell him to order some prami and give it a try. Make sure to tell him to start dosing low and work his way up. Some people have funky sides with prami, but I never had any.

 

[KaiserSose]

Ya I have no idea how high prolactin feels like but it has to be that all I can think of, he's going to start prami and if that doesn't work I think he's dropping the npp and just finishing the test

 

[Shovel]

I don't personally believe in the Test/Deca ratio. The problem is more likely linked to Prolactin side effects caused by nandrolone. If you keep your estrogen under control, prolactin side effects are very rare. I would recommend looking at the possible of dropping your estrogen by using an Aromitize Inhibitor such as Arimidex or Aromasin. I have ran test as low as 300 and nandrolone as high as 450 and had no problems (because i kept my estrogen low). This my man, has more fact than fiction to it. Again, i don't believe in the Test/Deca ratio myth. And several others are starting to agree.

Exactly bro! You've hit the nail on the head...

To battle Prolactin you must keep your Estrogen levels in check and the real reason you are getting Prolactin type gyno is Estrogen is out of control...

Here is some info on Prolactin and you'll be able to tie together how we induce it in ourselves...



Prolactin

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Prolactin is a single-chain protein hormone closely related to growth hormone. It is secreted by so-called lactotrophs in the anterior pituitary. It is also synthesized and secreted by a broad range of other cells in the body, most prominently various immune cells, the brain and the decidua of the pregnant uterus.

Prolactin is synthesized as a prohormone. Following cleavage of the signal peptide, the length of the mature hormone is between 194 and 199 amino acids, depending on species. Hormone structure is stabilized by three intramolecular disulfide bonds.

Physiologic Effects of Prolactin
The conventional view of prolactin is that its major target organ is the mammary gland, and stimulating mammary gland development and milk production pretty well define its functions. Such a picture is true as far as goes, but it fails to convey an accurate depiction of this multifunctional hormone.

It is difficult to point to a tissue that does not express prolactin receptors, and although the anterior pituitary is the major source of prolactin, the hormone is synthesized and secreted in many other tissues. Overall, several hundred different actions have been reported for prolactin in various species. Some of its major effects are summarized here.

Mammary Gland Development, Milk Production and Reproduction

In the 1920's it was found that extracts of the pituitary gland, when injected into virgin rabbits, induced milk production. Subsequent research demonstrated that prolactin has two major roles in milk production:

Prolactin induces lobuloalveolar growth of the mammary gland. Alveoli are the clusters of cells in the mammary gland that actually secrete milk.


Prolactin stimulates lactogenesis or milk production after giving birth. Prolactin, along with cortisol and insulin, act together to stimulate transcription of the genes that encode milk proteins.

The critical role of prolactin in lactation has been confirmed in mice with targeted deletions in the prolactin gene. Female mice that are heterozygous for the deleted prolactin gene (and produce roughly half the normal amount of prolactin) show failure to lactate after their first pregnancy.

Prolactin also appears important in several non-lactational aspects of reproduction. In some species (rodents, dogs, skunks), prolactin is necessary for maintainance of corpora lutea (ovarian structures that secrete progesterone, the "hormone of pregnancy"). Mice that are homozygous for an inactivated prolactin gene and thus incapable of secreting prolactin are infertile due to defects in ovulation, fertilization, preimplantation development and implantation.

Finally, prolactin appears to have stimulatory effects in some species on reproductive or maternal behaviors such as nest building and retrieval of scattered young.

Effects on Immune Function

The prolactin receptor is widely expressed by immune cells, and some types of lymphocytes synthesize and secrete prolactin. These observations suggest that prolactin may act as an autocrine or paracrine modulator of immune activity. Interestingly, mice with homozygous deletions of the prolactin gene fail to show significant abnormalities in immune responses.

A considerable amount of research is in progress to delineate the role of prolactin in normal and pathologic immune responses. It appears that prolactin has a modulatory role in several aspects of immune function, but is not strictly required for these responses.

Control of Prolactin Secretion
In contrast to what is seen with all the other pituitary hormones, the hypothalamus tonically suppresses prolactin secretion from the pituitary. In other words, there is usually a hypothalamic "brake" set on the lactotroph, and prolactin is secreted only when the brake is released. If the pituitary stalk is cut, prolactin secretion increases, while secretion of all the other pituitary hormones fall dramatically due to loss of hypothalamic releasing hormones.

Dopamine serves as the major prolactin-inhibiting factor or brake on prolactin secretion. Dopamine is secreted into portal blood by hypothalamic neurons, binds to receptors on lactotrophs, and inhibits both the synthesis and secretion of prolactin. Agents and drugs that interfere with dopamine secretion or receptor binding lead to enhanced secretion of prolactin.

In addition to tonic inhibition by dopamine, prolactin secretion is positively regulated by several hormones, including thyroid-releasing hormone, gonadotropin-releasing hormone and vasoactive intestinal polypeptide. Stimulation of the nipples and mammary gland, as occurs during nursing, leads to prolactin release. This effect appears to be due to a spinal reflex arc that causes release of prolactin-stimulating hormones from the hypothalamus.

****** Estrogens provide a well-studied positive control over prolactin synthesis and secretion. The increasing blood concentrations of estrogen during late pregnancy appear responsible for the elevated levels of prolactin that are necessary to prepare the mammary gland for lactation at the end of gestation.

Disease States
Excessive secretion of prolactin - hyperprolactinemia - is a relative common disorder in humans. This condition has numerous causes, including prolactin-secreting tumors and therapy with certain drugs.

Common manifestations of hyperprolactinemia in women include amenorrhea (lack of menstrural cycles) and galactorrhea (excessive or spontaneous secretion of milk). Men with hyperprolactinemia typically show hypogonadism, with decreased sex drive, decreased sperm production and impotence. Such men also often show breast enlargement (gynecomastia), but very rarely produce milk.

 

[Bullseye Forever]

Ya I have no idea how high prolactin feels like but it has to be that all I can think of, he's going to start prami and if that doesn't work I think he's dropping the npp and just finishing the test

KaiserSose,i have a friend who is running tren/sustanon,and he didnt even know what prolactin gyno was..and he came to me for advice lol....so i had him research and i think he is now gonna take either prami or dostinex

 

[bobbyb64]

Need your opinion on a cycle

Hi Guys,
Just noticed your thread about Deca and was curious if you could help me out with some tips on starting a cycle.
Just getting back into working out and need to know what a first cycle of Deca dosage would be.
Also, after reading your comments noticed test/deca mentioned.
I need to build some mass back. I weigh 214 at 6'.

What do you all suggest. I d appreciate any tips I can get.
Many Thanx.

 

[Bullseye Forever]

Hi Guys,
Just noticed your thread about Deca and was curious if you could help me out with some tips on starting a cycle.
Just getting back into working out and need to know what a first cycle of Deca dosage would be.
Also, after reading your comments noticed test/deca mentioned.
I need to build some mass back. I weigh 214 at 6'.

What do you all suggest. I d appreciate any tips I can get.
Many Thanx.

is this your first cycle? or have you done several before?.....most people use 400mg/week of deca thier first time using it...but not for thier first cycle though

 

[KaiserSose]

Problem with high prolactin is. Unless your lactating its hard to diagnose most people just chalk it up to high estro , I will run a preventative dose of prami for sure

 

[Bullseye Forever]

Problem with high prolactin is. Unless your lactating its hard to diagnose most people just chalk it up to high estro , I will run a preventative dose of prami for sure

yea i am too brother,im gonna run caber with mine,just in case,because im really prone to high estrogen conversion anyway,cause a friend of mine had high prolactin sides and was lactating,which he didnt do his homework first off,he had regular gyno on top of high prolactin gyno,since he starting taking aromasin and prami and hes had a tough time getting it under control

 

[bobbyb64]

is this your first cycle? or have you done several before?.....most people use 400mg/week of deca thier first time using it...but not for thier first cycle though

Actually, I did a couple of cycles over 10 years ago. I ve been away from exercising for that long and just trying to get back into it. Not trying to compete or anything since at 47 I m too old for that. Just trying to get fit again.
What do you recommend for building up some energy level since I feel weaker than then?
Many Thanx.

 

[KaiserSose]

Actually, I did a couple of cycles over 10 years ago. I ve been away from exercising for that long and just trying to get back into it. Not trying to compete or anything since at 47 I m too old for that. Just trying to get fit again.
What do you recommend for building up some energy level since I feel weaker than then?
Many Thanx.

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