Donating Blood and high RBC but low iron

rfins

New member
Test levels are mid 600-800 but I tend to get elevated hematocrit and hemoglobin levels.

If I donate double reds every 4 months I can keep levels in a normal range, but I have low iron- ferritin levels.

My Dr. suggested that I take some iron supplements but it seems that would only add to the high red blood count levels ????



Anyone else having this problem ?
 
I have this problem too and have not found a solution.

Doing apheresis donation instead of whole blood can help because RBCs are destroyed in the process but the iron they contained can be re-absorbed.
 
OP - what is your Iron (Hemoglobin) level? Assume you are donating at the red cross. I'm in the same boat - donating whole blood 5X a year to keep RBC in check - and its still slowly creeping up. I just donated last week and hemoglobin came in at 18, which is on the high side. I do take an iron supplement daily as donating blood frequently leads to low iron.

I don't have it in me (yet) to donate apheresis. Pumping blood back into me doesn't sound appealing...
 
OP - what is your Iron (Hemoglobin) level? Assume you are donating at the red cross. I'm in the same boat - donating whole blood 5X a year to keep RBC in check - and its still slowly creeping up. I just donated last week and hemoglobin came in at 18, which is on the high side. I do take an iron supplement daily as donating blood frequently leads to low iron.

I don't have it in me (yet) to donate apheresis. Pumping blood back into me doesn't sound appealing...

I have had hemoglobin at 17.7 - 18. - 18.1 hematocrit at 53.2 - 55.7 - 53.1
if I donate double reds 3 x a year I ran homoglobin at 15.2 16.4 - 16.5 hematocrit 45.5 - 49.6 - 50.2

I don't usually check iron but when I did it was low so the Dr. advised iron pills.
 
I have this problem too and have not found a solution.

Doing apheresis donation instead of whole blood can help because RBCs are destroyed in the process but the iron they contained can be re-absorbed.

I am not familiar with apheresis.........are the red cells donated or returned ?
I donate double reds to lower my RBC but it seems to deplete iron.
 
I am not familiar with apheresis.........are the red cells donated or returned ?
I donate double reds to lower my RBC but it seems to deplete iron.

I think double red cell donation involves apheresis. Apheresis means separating out some blood components and returning the rest. You can donate plasma, platelets or red blood cells by apheresis. I've only ever done the first two.

In platelet apheresis, the red blood cells are returned, but the process of pumping destroys a number of cells. The iron that they contained can be reabsorbed, which helps with iron loss.
 
Basically in healthy men their Ferritin should be around 125. Ferritin is the amount of protein bound iron in the blood referred to as storage iron. I tanked my iron stores donating blood. My last ferritin reading was 40, and i self phlebbed 2 pints after that. I found some injectible iron online, and after 200mg my ferritin is up to 100. To fix the HCT issue I found a blood bank with an older aphresis machine and was doing platelets monthly, a double platelet donation would drop my hematocrit 6%. To donate doubles my platelets would have to be 220 or higher. So I started taking supplements to get my platelet count up so I could get doubles. The newer machines dont induce as much hemolysis. I ended up going to a renown hematologist to find the solution to my HCT issue - which my insurance did not cover at all. I had known for over a year that I desaturate in my sleep, and I had been working with medical professionals and sleep specialists for it, and I kept bringing up that I needed oxygen in my sleep. They said it wouldnt help. The first thing this renown hemo said was get an oxygen concentrator and titrate oxygen into your cpap machine. The first week my HCT went down 1.5%, and within a month my HCT went from 53 to 48%, just adding 5 liters of oxygen per hour. It is so unbelievably frustrating to know the answer to my issue and yet being talked out of it by professionals. I had sleep studies saying i have apneas, and my cpap was working, yet i still desaturate. I got a recording pulse oximiter from amazon and check my o2 level. My average O2 saturation was around 92% before the o2 bleed, after its 97%. If you have problems with HCT, first switch to daily smaller doses. Metformin and Telemisartan/Losartan can also help. It just depends on what the underlying cause is. Clinically, o2 desaturation isnt an issue until its under 88% for a substantial period of time. So for me its not bad enough that I qualify for insurance coverage, but even little desaturations can cause the kidneys to make erythropoitien
 
Generally, a normal hematocrit range is considered to be: For men, 38.8 to 50 percent so your on the high side, Avoid foods that are rich in iron, drink lots of water.
 
I always recommend donation every 3 months for every patients. That is the longest time I will allow, some patients have to every month. Iron shouldn't be of a concern with therapeutic donation

Dr B.
 
I always recommend donation every 3 months for every patients. That is the longest time I will allow, some patients have to every month. Iron shouldn't be of a concern with therapeutic donation

Dr B.

I would like to understand your reasoning. Why are you not concerned about ferritin levels?
 
Not at all. We use ferritin more as as a pre cursor to the overall disgnosis of iron deficiency or anemia. We also use tibc factor to watch for this.


Dr b
 
From a Physicians standpoint, having high crit is more dangerous than low ferritin. So if a person donates too much they will just get iron deficiency anemia, which is treatable. If a person doesnt donate and their hematocrit goes to like 60%, a person is in much more danger of throwing a clot.
 
exactly, also it can reak havoc on the liver. Most sides are very treatable, however once you start messing with the liver its another ball game. Is called LIVEr for a reason :)


Dr. B
 
From a Physicians standpoint, having high crit is more dangerous than low ferritin. So if a person donates too much they will just get iron deficiency anemia, which is treatable. If a person doesnt donate and their hematocrit goes to like 60%, a person is in much more danger of throwing a clot.

Ordinarily this is true, and the blood centers certainly rely on correlation between ferritin and hemoglobin levels by only testing the latter.
However, the erythropoietic effects of AAS can significantly weaken or even negate this correlation.

Logic suggests that at some point ferritin could drop low enough so that production of RBCs is severely restricted, but what other health effects will such low ferritin levels bring? If anyone knows that answer I would be most interested.

I have low ferritin (22 [30-400]) and high HGB (17.8 [12.6-17.7]), and I'm sure I'm not the only one.
 
From a Physicians standpoint, having high crit is more dangerous than low ferritin.

Well there has never been a single documented case of TRT induced elevated HCT that caused a heart attack or stroke. Not 1.

Basically some people with heart attacks and stroke have elevated HCT, but there is no proven connection when HCT is elevated through exogenous testosterone. So the medical community thinks there COULD be a problem, but no one is sure. TC is going to raise your HCT, its what it does, its part of the reason you have more endurance when on TRT. If it reaches 55% thats when we suggest discontinuing TRT until you get it under control, but a level of 51 or 52 is not dreadfully dangerous in our opinion.

So I am not sure I can agree there. Low iron will basically negate the positive effects of your TRT regimen, and to treat it you have to take iron which will increase your HCT.

Donating every time the donation center will let you will almost certainly cause a iron deficiency, we have seen it many times.

So its actually quite a conundrum.

Hope this makes sense.
 
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