If you could only have five supplements.

Uk Boy

ENGLANDS FINEST
Which supplements would be your top five?
Heres mine.

1. Whey protein.
2. Dextrose.
3. Multi vit/min pack.
4. Vit C.
5. Cod liver oil.
 
Protein Powder
Fish Oil Caps
Ephedra/Caffeine/Yohimbine
MultiVit
I can't think of a #5

Really, I don't take very many supps. When I am bulking all I throw down is protein powder. I try and use creatine, but I take it for a couple days then I forget to take it for a week.
 
Whey protein
NAC
Green tea
multi vitamin/mineral
fish oil
 
gonzo said:
This is the 2nd time I have seen CoQ10 what is this. I can't find anything on it.

Taken from: Here

CoQ10 is a naturally occurring nutrient found in each cell of the body. CoQ10 was first identified by University of Wisconsin researchers in 1957. CoQ10 is found in foods, particularly in fish and meats. In addition to playing a significant role in the energy system of each of our cells, CoQ10 is a good antioxidant. Studies with CoQ10 have mostly focused on its role in improving certain types of cardiovascular diseases, including congestive heart failure and hypertension. However, CoQ10 benefits brain function, too. Many who take CoQ10 notice that this nutrient provides energy and mental clarity.

How does CoQ10 work?
Each cell in the body needs a source of energy to survive, so cells break down sugars, fats, and amino acids to make energy. Small enclosures within cells that make this energy are called mitochondria. CoQ10 exists naturally in our mitochondria and carries electrons involved in energy metabolism. CoQ10 is essential in the production of adenosine triphosphate (ATP), the basic energy molecule of each cell. In the bloodstream, CoQ10 is mainly transported by lipoproteins such as LDL (low-density lipoprotein) and HDL (high-density lipoprotein). It is thought that CoQ10 is one of the first antioxidants to be depleted when LDL is subjected to oxidation. Hence, CoQ10 is an important nutrient that prevents the oxidation of lipoproteins, thus potentially reducing the risk of arteries from forming plaques and getting damaged. In healthy individuals, CoQ10 is found in high concentrations in the heart, kidneys, and liver.

CoQ10 Benefits
Heart Attacks: In a small trial of patients with recent myocardial infarction, CoQ10--used in addition to aspirin and cholesterol-lowering drugs--decreased the likelihood of further cardiac events for at least one year after the heart attack. The dosage of CoQ10 used in the study was 60 mg twice daily.

Hypertension: CoQ10 may help lower blood pressure. Although early studies indicated that CoQ10 may be beneficial in heart failure, newer studies with patients in stage III or IV heart failure have not found CoQ10 to be helpful.

CoQ10 may be beneficial in diabetics. It helps improve the function of endothelial cells lining blood vessels and may slightly help with blood sugar control.

Parkinson's Disease: A small but promising study found that coenzyme Q-10, or CoQ10, may help stop the nerve cell death that characterizes Parkinson's. disease. The study involved just 80 people. Half ate maple-nut flavored wafers containing various CoQ10 doses, half took a placebo for up to 16 months. By the study's end, the 23 patients on the highest daily doses had 44 percent less decline in mental function, movement and ability to perform daily living tasks than the placebo group. Research has suggested that energy-supplying structures inside cells called mitochondria may be impaired in Parkinson's disease. CoQ10, a compound made in the body, is believed to help mitochondria function. Patients studied had early-stage Parkinson's and took a placebo or CoQ10 in doses of 300 milligrams, 600 mgs or 1,200 mgs daily. Their symptoms were evaluated for up to 16 months. By the eighth month, the 23 patients on the highest dose showed significantly less impairment than the others. Side effects, including back pain, headaches and dizziness, were mostly mild.
Dr. Sahelian comments: I'm surprised these patients could tolerate these very high doses of CoQ10. I have had feedback from those using high doses of CoQ10 that, in some people, there is excessive stimulant-like effect and high levels of alertness that may cause insomnia.

CoQ10 and Drug interactions
The administration of CoQ10 and warfarin does not significantly affect the anticoagulant effect of warfarin in rats. A Human trial shows Co Q10 and Ginkgo biloba do not influence the clinical effect of warfarin.

The Author’s Experience with CoQ10
The effect from 30 mg of CoQ10 is mild, mostly consisting of a slightly higher energy level. The effects become more noticeable with 60 mg. I have taken up to 100 mg in the morning. On this dose, I notice an increase in energy as the day goes on, with an urge to take a long walk or be physically active. There is enhanced focus, motivation, and productivity, along with the desire to talk to people. The 100-mg dose of CoQ10, though, is too much since I feel too energetic and alert even in late evening when I want to slow down and get ready for sleep. I usually do not recommend may patients take more than 10 to 30 mg of CoQ10 on a long term basis

CoQ10 Research Update
Effect of coenzyme Q10 on risk of atherosclerosis in patients with recent myocardial infarction.
Singh RB, Neki NS, Kartikey K, Pella D, Kumar A, Niaz MA, Thakur AS. Mol Cell Biochem. 2003 Apr;246(1-2):75-82.
Medical Hospital and Research Centre, Moradabad, India. icn@mickyonline.com
In a randomized, double-blind, controlled trial, the effects of oral treatment with coenzyme Q10 (CoQ10, 120 mg/day), a bioenergetic and antioxidant cytoprotective agent, were compared for 1 year, on the risk factors of atherosclerosis, in 73 (CoQ, group A) and 71 (B vitamin group B) patients after acute myocardial infarction (AMI). After 1 year, total cardiac events (24.6 vs. 45.0%, p < 0.02) including non-fatal infarction (13.7 vs. 25.3%, p < 0.05) and cardiac deaths were significantly lower in the intervention group compared to control group. The extent of cardiac disease, elevation in cardiac enzymes, left ventricular enlargement, previous coronary artery disease and elapsed time from symptom onset to infarction at entry to study showed no significant differences between the two groups. Plasma level of vitamin E (32.4 +/- 4.3 vs. 22.1 +/- 3.6 umol/L) and high density lipoprotein cholesterol (1.26 +/- 0.43 vs. 1.12 +/- 0.32 mmol/L) showed significant (p < 0.05) increase whereas thiobarbituric acid reactive substances, malondialdehyde (1.9 + 0.31 vs. 3.1 + 0.32 pmol/L) and diene conjugates showed significant reduction respectively in the CoQ group compared to control group. Approximately half of the patients in each group (n = 36 vs. 31) were receiving lovastatin (10 mg/day) and both groups had a significant reduction in total and low density lipoprotein cholesterol compared to baseline levels. It is possible that treatment with CoQ10 in patients with recent MI may be beneficial in patients with high risk of atherothrombosis, despite optimal lipid lowering therapy during a follow-up of 1 year. Adverse effect of treatments showed that fatigue (40.8 vs. 6.8%, p < 0.01) was more common in the control group than CoQ10 group.
 
theHULK9281 said:
Taken from: Here


I've been reading a bit on Q10 recently.

It seems like a preventative therapy to me. Am I missing some immediate benefit?

"In healthy individuals, CoQ10 is found in high concentrations in the heart, kidneys, and liver."
 
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