Injection limitations.. Help?

Powerstroke32

New member
Hey guys, I was wondering what were the limits to injecting a certain amount of gear into different sites? EX: what is the most I can inject into My thighs or ass check?? and how?? I'm planning on getting some more test but it's 250mg and I plan on taking two CC's to get 500mg.. I had wanted to get the 500mg at once and just shoot 2CC's into thigh but wanted opinions and advice first.. or should I split the injections 250mg one day and another shot the next??? how should I go about this and what do you guys do?

thanks
 
2 cc's in thigh or glute is nothing, but if you are only doing 500mg/week, then you are best to split the injections up to twice a week in order to maximixe stable blood hormone levels.
 
2 cc's in thigh or glute is nothing, but if you are only doing 500mg/week, then you are best to split the injections up to twice a week in order to maximixe stable blood hormone levels.


ok, so at what time duration should I split the injections? also at a more frequent injection I should be ok as far as scar tissue goes?
 
ok, so at what time duration should I split the injections? also at a more frequent injection I should be ok as far as scar tissue goes?

space them evenly throughout the week however is convenient and keep them constant

like monday and thursday or tuesday and friday ect
 
I don't know why so many people are hooked on twice a week injections. Just "Broscience" I guess. Testosterone cypionate/enanthate injections should be done once a week. Your body doesn't know what a week is. Go by the half life of the ester. Dont cut it short, dont leave it long.

If its test C or E, do an every 5th-6th day shot. Straight from drugs.com: The half-life of Testosterone Cypionate when injected intramuscularly is approximately eight days.

I know, this is against everything on every thread of every board, but "technically" speaking, its the right way.

Injecting every 3-4 days like most people do isn't necessary. The average half life of the cypionate ester is 8 days, some say 6.5. Inject once a week. Injecting more than necessary only brings more chance of risk for infection and all that.

Ask any doctor what the "best" way to supplement an injectable drug with the half life of 8 days is, and he will tell you to do it every 8th day.

/Rant.
 
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Good point PA

It would be except for the fact that he is wrong about the half-life of cyp being 8 days.

The half-life of cypionate is more like 5 or 6 days.

Even if he was right about it being 8 days (which is incorrect), injecting once a week still allows for a big fluctuation in blood hormone levels between injections.

Another point to consider is, the more stable you keep blood hormone levels (with frequent injections), the less negative side effects you will experience. That come from experience, not something written in drugs.com where they have no idea about what we as bodybuilders do and experience.

As for that statement about more chance of infections and all that, if you are using clean gear and injection protocol, you have nothing to worry about. That is just another scare tactic to prove his point of view. If you are that worried, you may as well find another hobby, perhaps needlepoint......lol
 
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PA, take a look at this:

6413d1139879356-sustanon-100-anyone-on-riu_5suppl1_s22.pdf -- FileFactory.com - free file hosting --

The true half-life of test enan once it has hit serum is probably only a few days or even hours but nevermind that. The depot is a time-release mechanism to help with that.

If you look at bioavailable testosterone, which is really what counts, you will see that its taken a pretty hard hit by day 7.

These aren't typical drugs. There are hormones. Waiting for the half-life prior to injecting again means that levels will be unstable. That means increased water retention and a changing androgen:estrogen ratio. If you take a drug like Allegra however, the body doesn't care as much. Either the dose is an effective dose until the next dose or it is not. hormones are much more complicated than that.

Can you get away with once weekly injections? Yes. It is optimal? In my opinion, no.
 
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Drugs.com lied to me. I read another thing that said Anthony Roberts...yea...i guess i could just stop there...said after numerous tests he found the half life of cypionate was 6.6 days. I haven't looked anything up on enanthate. I just remember having to memorize a huge list of esters ans their half lives in one of my biochemistry classes, and the cypionate ester was something like 6-8 days. Im sure its different in everyones body.
 
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It would be except for the fact that he is wrong about the half-life of cyp being 8 days.

The half-life of cypionate is more like 5 or 6 days.

Even if he was right about it being 8 days (which is incorrect), injecting once a week still allows for a big fluctuation in blood hormone levels between injections.

Another point to consider is, the more stable you keep blood hormone levels (with frequent injections), the less negative side effects you will experience. That come from experience, not something written in drugs.com where they have no idea about what we as bodybuilders do and experience.

As for that statement about more chance of infections and all that, if you are using clean gear and injection protocol, you have nothing to worry about. That is just another scare tactic to prove his point of view. If you are that worried, you may as well find another hobby, perhaps needlepoint......lol

lol. I do always find that towards the end of a cycle I would always be sick of injecting, and most of my injection sites would stay hurting longer. The only other thing I was basing my assumption off of was the pullout on my Androgel Packet, which did a study with test cypionate. It has a graph showing how your hormoned fluctuate in a 2 week period. The peak of the graph was around day 7. Day 6 and 8 were very close to the peak, day 9-10 were lower, and obviously after that they were very low.
 
According to this study: Pharmacokinetics and pharmacodynamics of testoster...[Acta Endocrinol (Copenh). 1990] - PubMed Result

The average half life of test enan is 4-7 days. I think if someone were to want "500mg" a week, and instead injected 450mg every 4 days, they would see the same results, with equal sides. But thats just me. You guys have more experience than I do. Im just basing my assumption off of books and studies.
Say the half life is 4 days. That means that half of the prior injection is gone four days later. So blood levels might go from 4k to 2k in 4 days. Even lower after 7 days.

I think it is pretty well established that the serum levels of testosterone make a difference.

But weekly injections aren't the end of the world. I very much agree with that. If there is a compelling reason to only inject weekly, then so be it.

Uncontrolled infection should be a non-issue. If your injection technique or gear are causing near-injections then the cycle needs to come to a stop.
 
Very true. I always found half-lives sort of weird, even in school. Say the half life was 7 days, for say Test Undecaonte. If you were injecting 1000mg every 7 days, lets say it gave you a serum level of 4000 at the peak, and 2000 at day 7. You continue this the whole cycle, with a gradual weekly fluctuation from 4000-2000ng/dl.

Now lets say you inject 500mg every 3.5 days. "theoretically speaking" wouldnt that mean that your levels, initially, would be 2000ng/dl (in this example). Now you inject 500mg 3.5 days later, to give your 1g a week. In those 3.5 days, your blood drops from 2000ng to 1500ng. You then inject 500mg more on the 3.5th day. Your levels now are at 3500k (2000ng because of that days injection, and 1500ng from the previous injection). Another 3.5 days go by. The first shot is now giving you a level of 1000ng, the 2nd shot, 1500ng, and that days shot, 2000ng. Now your level is at 4500. Another 3.5 days goes by. The first shot, 500ng, the second shot, 1000ng, the third shot, 1500ng, and the 4th shot, 2000ng. Now you're at 5000ng.

Wouldnt that make your serum levels go up each shot? There is no roller coaster, but instead a constant increase. Is that what we are going for with cycles?

Now lets say you just did 1g shot every week. Shot 1, 4000ng, day 7, 2000ng + 4000ng. day 14, 1000ng, + 2000ng, + 4000ng. After 2 weeks you're at 7000.

This is probably nothing like it actually works, as there are tons of factors that determine your test level, but I can kind of see now why people inject twice a week. There would never be a drop in serum levels, and they increase slower, whereas a weekly injection increases faster, but causes a drop each week.


Maybe this is why frontloading works.

I think this makes sense why testosterone replacement therapy (TRT) protocol is standard for every 2 weeks. Using the example above, and pretending testosterone replacement therapy (TRT) was 200mg every 2 weeks, giving a level of 800ng/dl then after two weeks you would have a level of 200ng/dl. after 4 weeks it would be 250, and so on. Very low levels that increase very slowly...but...horrible hormonal shifts.


I just probably wasted 15 minutes of my life for no reason.

Oh, and what makes no sense to me about all this, every chart ive seen on any pharmacy pamphlet from androgel or test cyp, and my doctor, says that your levels "peak" at the half life of the ester, and then drop the day following the time the body has metabolized the ester. This makes more sense to me, but what do i know lol. So basically he said a test cyp injection peaks at day 7, where you guys are saying it would be half of your normal serum level.

Fucking biochemistry.
 
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It doesn't matter to me too much of what I read as what I experience. I will still do cyp , enant twice each wk. If it aint broke don't fix it.
I know a guy who did 750mg Sus once each wk all in one shot and it seemed to work for him , just to look at him would tell me it worked for him. Unless he was lying.
 
Very true. I always found half-lives sort of weird, even in school. Say the half life was 7 days, for say Test Undecaonte. If you were injecting 1000mg every 7 days, lets say it gave you a serum level of 4000 at the peak, and 2000 at day 7. You continue this the whole cycle, with a gradual weekly fluctuation from 4000-2000ng/dl.

Well, if you only do 2 injections then it works out like this, but as the weeks go by you still have the nearly all of the prior weeks to consider. For example:

Week -> injected -> amount left at end of week
----------------------------------------------
1 -> 500 -> 250
2 -> 500 -> 375
3 -> 500 -> 437.5
4 -> 500 -> 468.75
5 -> 500 -> 484.375
6 -> 500 -> 492.1875
etc

Seems pretty stable but you have to consider that this is the effective dose at the end of each week just prior to injection. The numbers spike significantly shortly after each injection ... maybe 800.

So frontloading is to avoid this buildup and just get it done with but it doesn't make levels more stable from injection to injection.
 
I think this makes sense why testosterone replacement therapy (TRT) protocol is standard for every 2 weeks.
Appropriate testosterone replacement therapy (TRT) is most definitely not every 2 weeks. The package insert says inject every 2-4 weeks but those instructions are crap and any decent testosterone replacement therapy (TRT) doc will validate this. My wife's pharmacology book cites the unstable hormone levels as a disadvantage of the injections. The solution is pretty simple: inject more frequently.

So why don't they just update the package insert? Because it isn't that simple. The FDA will insist on formal clinical evidence. This costs the pharma companies millions and millions of dollars.

Instead, prescriptions for Androgel and maybe Testim continue to increase.
 
Appropriate testosterone replacement therapy (TRT) is most definitely not every 2 weeks. The package insert says inject every 2-4 weeks but those instructions are crap and any decent testosterone replacement therapy (TRT) doc will validate this. My wife's pharmacology book cites the unstable hormone levels as a disadvantage of the injections. The solution is pretty simple: inject more frequently.

So why don't they just update the package insert? Because it isn't that simple. The FDA will insist on formal clinical evidence. This costs the pharma companies millions and millions of dollars.

Instead, prescriptions for Androgel and maybe Testim continue to increase.

Excellent post !!
 
Lol, it was a good brawl, GL won, but at least now I understand something more.

Funny that this is hardly discussed on the boards, yet it's very important. I guess most guys just follow the rules and just dont ask questions.

I ask questions.

Sorry for murdering your thread PowerStroke lol

Best thing I got out of it is I understand why frontloading works now, and why it wakes 4 weeks for your cycle to really kick in. I always knew thats just how it was...but now i know why.
 
I don't know why so many people are hooked on twice a week injections. Just "Broscience" I guess. Testosterone cypionate/enanthate injections should be done once a week. Your body doesn't know what a week is. Go by the half life of the ester. Dont cut it short, dont leave it long.

If its test C or E, do an every 5th-6th day shot. Straight from drugs.com: The half-life of Testosterone Cypionate when injected intramuscularly is approximately eight days.

I know, this is against everything on every thread of every board, but "technically" speaking, its the right way.

Injecting every 3-4 days like most people do isn't necessary. The average half life of the cypionate ester is 8 days, some say 6.5. Inject once a week. Injecting more than necessary only brings more chance of risk for infection and all that.

Ask any doctor what the "best" way to supplement an injectable drug with the half life of 8 days is, and he will tell you to do it every 8th day.

/Rant.


BUDDY I KNOW its better i got 1/8th the acne i got when using it only 1 time a week now its 2 shots a week and i CAN tell i have less sides like acne.
I mean its not a big deal you will live with 1 time a week for long ester but i also agree with Stonecold about 2 times a week being better wiht being 500mg a week.

something even weirder is im taking eod this cycle and have less sides then wheni did 500mg ew of testE and right now im on 250mg eod ??? fugure that out? lol "its omnadren thow"
 
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