Interesting fact about steroids....

[needsize]

A few weeks ago I was sent to a specialist to see about my rotator cuff. We talked about the kind of cycles that I was running, and he asked me if I knew the effect steroids had on connective tissues. I told him what I knew about how when you're on how you strength increases faster than your tendons can keep up with, so injuries are common. He agreed, but had something to add; apparently anabolic steroids interfere with the bodies ability to heal/rebuild connective tissues. So not only do you have to worry about injuries because you get strong so fast, but the steroids will interfere with your body's ability to fix any damage that you do.
Some food for thought....

 

[Rj*]

that's bad news

 

[staybig]

that does not sound good...

 

[stonecold54]

they most likely put out of whack the balance of cortico steroids and anabolic/androgenic. we pump our bodies full of the muscle building ones that the repair and anti inflammatory steroids must not work as effeciently. just my thought don't know if it is true

 

[Popichulo]

HMMM I see......

 

[bigdelt69]

and dont cortico steroids play an important roll in the bodys immune function?..

 

[stonecold54]

in a way they contain infection and swelling so they do play a role in healing.

 

[LAWNSAVER]

I know that Winstrol has positive effects on tendons and ligaments. GH too is a good addition!

Glucosamine and Chondriton is a must in the IRON GAME!!

 

[staybig]

how does winstrol have a postive affect on muscle why does test or tren do the same????

 

[saturn]

I was told the same thing by a Dr. several years ago when I went in for shoulder surgery. I was told that my steroid use probably was a factor in my injury and would hinder my ability to recover.

 

[Doc Banner]

lots of juice messes up your bodies ability to produce collagen (what makes skin elastic, tendons, ligaments, etc...) propery.....

 

[EmptyWallet]

Well this is no good, I've read about alot of guys healing alot quicker from ACL surgeries when they took some deca and maybe a little test post surgery when they were going through recovery and rehab. I have ACL surgery on the 8th of May hopefully and I was going to take deca post surgery to speed the healing. Couple of guys said it really advanced their ACL recovery and protocol. This is not good news to me if its true.

 

[RoadHouse]

Although winstrol increases collagen synthesis suprisignly

 

[RoadHouse]

Stimulation of collagen synthesis by the anabolic steroid stanozolol.

Falanga V, Greenberg AS, Zhou L, Ochoa SM, Roberts AB, Falabella A, Yamaguchi Y.

University of Miami School of Medicine, Department of Dermatology, Miami Veterans Affairs Medical Center, Florida, USA.

There is evidence that anabolic steroids, which are derived from testosterone and have markedly less androgenic activity, promote tissue growth and enhance tissue repair; however, the mechanisms involved in their anabolic activities remain unclear. In this report, we measured the effect of the anabolic steroid stanozolol on cell replication and collagen synthesis in cultures of adult human dermal fibroblasts. Stanozolol (0.625-5 microg per ml) had no effect on fibroblast replication and cell viability (p = 0.764) but enhanced collagen synthesis (p < 0.01) in a dose-dependent manner (r = 0.907). Stanozolol also increased (by 2-fold) the mRNA levels of alpha1 (I) and alpha1 (III) procollagen and, to a similar extent, upregulated transforming growth factor-beta1 (TGF-beta1) mRNA and peptide levels (p < 0.001). There was no stimulation of collagen synthesis by testosterone. The stimulatory effects of stanozolol on collagen synthesis were blocked by a TGF-beta1 anti-sense oligonucleotide, by antibodies to TGF-beta, and in dermal fibroblast cultures derived from TGF-beta1 knockout mice. We conclude that collagen synthesis is increased by the anabolic steroid stanozolol and that, for the most part, this effect is due to TGF-beta1. These findings point to a novel mechanism of action of anabolic steroids

 

[RoadHouse]

The effect of anabolic steroids on the biomechanical and histological properties of rat tendon.

Miles JW, Grana WA, Egle D, Min KW, Chitwood J.

University of Oklahoma Health Sciences Center, Oklahoma City.

Twenty-four male rats were divided into four groups, with anabolic steroids and exercise as variables. Biomechanical tests and histological evaluations were performed. The results of the biomechanical tests suggested that anabolic steroids produce a stiffer tendon, which fails with less elongation. The energy at the time when the tendon failed, the toe-limit elongation, and the elongation at the time of the first failure were all affected significantly. Changes in the force at failure were not statistically significant. No alterations of structure were noted when the specimens were viewed with light microscopy. Alterations of the sizes of the collagen fibrils were noted on electron microscopy.


Int Orthop 1987;11(2):157-62 Related Articles, Links

 

[Gredavcox]

Interesting......

 

[RoadHouse]

There are so many studies contridicting another one you have read, it seems you never really know if what your reading is the case 100% of the time

 

[EmptyWallet]

The effect of anabolic steroids on the biomechanical and histological properties of rat tendon.

Miles JW, Grana WA, Egle D, Min KW, Chitwood J.

University of Oklahoma Health Sciences Center, Oklahoma City.

Twenty-four male rats were divided into four groups, with anabolic steroids and exercise as variables. Biomechanical tests and histological evaluations were performed. The results of the biomechanical tests suggested that anabolic steroids produce a stiffer tendon, which fails with less elongation. The energy at the time when the tendon failed, the toe-limit elongation, and the elongation at the time of the first failure were all affected significantly. Changes in the force at failure were not statistically significant. No alterations of structure were noted when the specimens were viewed with light microscopy. Alterations of the sizes of the collagen fibrils were noted on electron microscopy.


Int Orthop 1987;11(2):157-62 Related Articles, Links

So, that study you posted, I'm guessing it says that Anabolic Androgenic Steroids (AAS) has a positive effect on Tendon and ligament strength and size? Stiffer tendon.....less elongation...is that good?

 

[RoadHouse]

the more a tendon or ligament strectches, the weaker it becomes

 

[EmptyWallet]

Ah, so this is a good thing for my ACL reconstruction correct?