Peak and Trough Levels - Once a Week VS Twice a Week Injections

[Next Level]

Hopefully someone here has some thoughts on the matter. I'm prescribed 100mg weekly done as a self injection. I recently switched to twice weekly injections of 50mg per injection (my endo doesn't know and I don't think he would understand as he was reluctant to order once weekly but did after I insisted - he initially prescribed 200mg every 2 weeks). I'm coming up the 3 month mark on TRT and my endo wants me to do bloodwork in early Feb.

I will be doing the bloodwork on the day before my injection so my trough. Will twice weekly injections create a higher trough than once weekly?

I would prefer a bump up in my dosage and would like to know what effect twice weekly injections will have.

Thanks guys!

 

[DreDay187]

Hopefully someone here has some thoughts on the matter. I'm prescribed 100mg weekly done as a self injection. I recently switched to twice weekly injections of 50mg per injection (my endo doesn't know and I don't think he would understand as he was reluctant to order once weekly but did after I insisted - he initially prescribed 200mg every 2 weeks). I'm coming up the 3 month mark on TRT and my endo wants me to do bloodwork in early Feb.

I will be doing the bloodwork on the day before my injection so my trough. Will twice weekly injections create a higher trough than once weekly?

I would prefer a bump up in my dosage and would like to know what effect twice weekly injections will have.

Thanks guys!

Halfwit and Megatron are the TRT guys that can answer this but I believe (could be wrong) that the size of the actual trough or drop off in plasma levels will be less with twice weekly injections vs weekly injection BUT the plasma levels of a weekly injection will remain consistently higher. So with twice weekly injections you won't get as high plasma levels and the trough show lower test levels but the fall off from peak value isn't as drastic which is why many prefer more frequent injections. The difference between peak and trough isn't as drastic. Hope that answers your question.

 

[methos0123]

The answer to your question is yes, it will have a higher trough value because the trough will be closer to your peak than it would if you injected only once a week. However, peak and trough was higher for me at the same dose, but injected 3.5 days apart instead of 7. It was double with higher frequency at the same dose...Might wanna order your own labs from privatelabs to see what your level is before you go to your doc.

 

[Next Level]

The answer to your question is yes, it will have a higher trough value because the trough will be closer to your peak than it would if you injected only once a week. However, peak and trough was higher for me at the same dose, but injected 3.5 days apart instead of 7. It was double with higher frequency at the same dose...Might wanna order your own labs from privatelabs to see what your level is before you go to your doc.

Good idea. It's a bit of a drive to do so but is worth considering as I'm in Canada. I did some bloodwork in early Jan at private labs down in AZ and had a peak (2 days after 100mg injection) of 966.

I'm torn whether I should maintain by twice weekly protocol or maybe do a 100 mg injection a week before my Feb bloodwork.

 

[Spunkey71]

Has your doctor prescribed you HCG? From the reading I have done, if you add HCG to your TRT protocol you only need to inject Test once a week as the HCG helps to maintain study serum levels.

 

[jomamma007]

just do twice a week and test bloods day of injection before injecting, after a month.

 

[Next Level]

Has your doctor prescribed you HCG? From the reading I have done, if you add HCG to your TRT protocol you only need to inject Test once a week as the HCG helps to maintain study serum levels.

No HCG but have researched it and will likely start it once I want to start a family.

 

[Brunodk]

No HCG but have researched it and will likely start it once I want to start a family.

If you're thinking about starting a family down the road I would suggest starting HCG immediately instead of letting things shut down for a while and then hoping you can get things working again. In my opinion, the relatively low cost of HCG makes it worthwhile all the time. Frankly anything that can aid in reproduction is worth it (This coming from a guy that spent $20,000 on IVF to have my first daughter).

 

[Alpin]

No HCG but have researched it and will likely start it once I want to start a family.

I did the same as you when fist starting out with TRT...
You're best to include it now and keep the horse near the stables (so to speak)...
it's better than chasing the horse all over the country side.
Leydig cells atrophy and I don't know your background completely, but if u had marginally low Endogenous T prior to TRT...
u could attempt a recovery of them if you ever had to stop TRT for any reason....
HCG keeps the factory going....
To keep a long story short...
I had 500 ng/dl natty T and never used HCG while on for quite a while....
came off TRT and can only recover to 291 n/dl....
Had I used HCG things could be better natty wise for me.