My_Pitch27
New member
Exactly..was this research adex?
Seemed like it wasnt working to begin with..
Compounding pharmacy with my name on it.
Exactly..was this research adex?
Seemed like it wasnt working to begin with..
That I can agree with, but it's common for testosterone levels to be much lower in the case of a pituitary tumor, hence why it's a major cause of secondary hypogonadism. This is also why I feel it would be good to see those LH/FSH levels as these are generated in the pituitary gland.I agree though, it doesn't really matter what we think as none of us are doctors and the best we can do is guess and shouldn't be taken as a substitute for medical care. The only reason I have an inkling for any of this is because of my own case of hypogonadism that was overlooked by many doctors over the years, leading me to have to do my own homework over the years.
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Here are my results guys.... My endo said my pituitary is overcompensating and this is normal (she knows the deal)... but said that I have a bit of Hypothyroidism (based on labs prior to me taking Tetosterone) and prescribed me levothyroxine 25mcg 1x day... any advice on this? I don't know anything about a slightly over active thyroid.
5/13/13
Estrogen 177 range 130 or less
FSH 11.0 range 1.6-8.0
LH 26.6 range 1.5-9.3
Total Testosterone 1032 range 241-827
5/17/13 ( I had another blood test a few days later to compare )
Estradiol (e2) 96 range 39 or less
FSH 12.7 range 1.6-8.0
LH 29.2 range 1.5-9.3
Total Testosterone 1152 range 241-827
thanks guys
Crikey! Your pituitary gland is having a field day! I've NEVER seen LH/FSH that high, that's impressive. She believes that to be normal and is only prescribing T4? I'd ask her to get an MRI just to rule out a tumor as suggested by Beck-Miester. I know clomid can induce the release of these hormones, but that's just...wow! Do you have a follow up appointment with her?
Well, those are pretty crazy numbers man. I would have expected to see them either at really low values (meaning it was still exogenous test) or around 3-4 each, meaning you're making a recovery and just had some rebound from your Aromatase inhibitor (AI). You're not at dangerous levels of estradiol imho, but I would keep an eye out for sides of being that high such as itchy nipples and let your endo know. Hopefully your doc knows more than us in this case and is right that it's just some sort of compensatory response and it resolves on its own. The blood test in 3 weeks will tell us for sure (hopefully).I do have a follow up appointment with her in a month. I asked her if it were possible that it was a tumor and she said no. I have another blood test in 3 weeks. Is it really that crazy? I mean I feel like my body is just bouncing back? What are your thoughts
Well, those are pretty crazy numbers man. I would have expected to see them either at really low values (meaning it was still exogenous test) or around 3-4 each, meaning you're making a recovery and just had some rebound from your Aromatase inhibitor (AI). You're not at dangerous levels of estradiol imho, but I would keep an eye out for sides of being that high such as itchy nipples and let your endo know. Hopefully your doc knows more than us in this case and is right that it's just some sort of compensatory response and it resolves on its own. The blood test in 3 weeks will tell us for sure (hopefully).
You have bounced back, just a bit more than it's "supposed" to. I didn't mean to scare you if I sounded too shocked. The human body just continues to amaze me sometimes.![]()
Yeah I'm hoping that my body is just bouncing back hard and thats just what I have to go through.... i will post next labs as well.... until then, i'm researching on hypothyroidism...damnitt!
I hope so too, it would be a definite learning experience for both of us as I had never heard of this happening! I wish I could help you more with the hypothyroidism, but I am woefully uneducated in that department.![]()
I hope so too, it would be a definite learning experience for both of us as I had never heard of this happening! I wish I could help you more with the hypothyroidism, but I am woefully uneducated in that department.![]()
LOL!! I think that HW and I have FAR too much in common....a deep seated desire for knowledge about this stuff: As soon as you mentioned hypothyroidism, I started my scouring of the web. I know that it's wikipedia, but it covers the "basics" of the HPT axis, and how the thyroid affects the pituitary..: Hypothalamic?pituitary?thyroid axis - Wikipedia, the free encyclopedia
Its actually an interesting read...
I've heard good things about levo, currently trying to get my sister to switch to levo from synthroid as the sides are almost as bad as her hypothyroidism. She's also got diabetes along with the hypothyroidism but her doctor refuses to consider any other medications. Do you happen to have the results for your labs from before the testosterone cycle? I'd be interested in seeing some of your numbers. I'm not exactly sure on what "physical" symptoms you may have of the hypothyroidism but if its not bad maybe wait until your body returns back to normal from after the cycle and get another test done to verify your thyroid is under active. It seems to me (at least the way you worded it) that your doctor wasn't 100% sure but was more apt to treat possible issues before they arose.
You're absolutely right. She said it's a possibility but not definite. Here are my lab results (mind you, these are prior to taking anything and my first complete panel) from january, which is what she went off of for the thyroid problem. I think I'm going to wait a month or two and get re checked for everything then consider taking the levo medication for my thyroid. I'm a believer that one lab test doesn't determine my end results anymore.
Lab from 1/2/2013
T3 Uptake 36 range 22-35%
T4(thyroxine) 5.1 range 4.5-12.0
TSH 3.94 range 0.40-4.50
If anyone else can shed some slight on this subject, please feel free
* If there is a suspicion of Hashimoto***8217;s Thyroiditis, I include TPO (Thyroid PerOxidase) and ATA (Antithyroglobulin Antibody). I also use this to monitor the severity of the Hashimoto***8217;s Thyroiditis and to see if therapy is working.
* If there is suspicion of Grave***8217;s Disease, I include TSI (Thyroid-Stimulating Immunoglobulin).
Which lab values are the most meaningful? Lab reports tend to provide only the high and low limits of ***8216;normal***8217; values. Since we are striving for ***8216;optimal***8217;, the ranges for optimal are noted below along with standard lab high and low values. These optimal range values are based on my observation of nearly 5,000 patients and reflect the lab test values that my healthiest patients tended to have, e.g. a professional tennis player with a sprained ankle. Remember that the optimal zone is an approximation and that it is meant to be used as a rough guide. People can feel well outside the optimal range but the chances of feeling well become more remote the further we get from the optimal zone. Note that laboratory techniques for these tests vary and lab values may have a 5-10% margin of error depending on the laboratory used.
Test Lab Low Optimal Range Lab High
TSH 0.5 1.3-1.8 5.0
Free T4 0.8 1.2-1.3 1.8
Free T3 230 320-330 420
Free T3* 2.3 3.2-3.3 4.2
*Some labs divide FT3 results by 100 thus 230 is the same as 2.3, etc.
In the cases of Free T4 (FT4) and Free T3 (FT3), the optimal zone is roughly half way between the usual lab normal Low-High values. Note that the normal range for these hormones may change a bit from lab to lab. In the case of TSH, the optimal zone is skewed far toward the low end of the standard lab Low-High range.
It's the TSH that triggered the hypo diagnosis. Anything over 3 is usually pre-hypothyroidic and under 1 is hyperthyroidic. HAH, I did know something of value....maybe? Do you really think his high E2 is THAT out of ratio to cause this Doc? Like I stated earlier, I'm definitely not well versed at all in thyroid issues, but I thought as long as the ratio was at LEAST 10:1 - there shouldn't be any major impact on the rest of the HPTA?
I'm not well versed either just what I've learned to help my sis out but I was referring to the hypothyroidism diagnosis. The high levels of estrogen may have played a role in the hypothyroidism which is why I'd like to see if he had a test/estradiol panel done before hand and what the numbers were. This is like asking what came first the chicken or the egg. Whether the thyroid or pituitary is affecting the HPTA or vice versa I'm not educated enough to tell. You can see though from the 2tests he posted last, his natty test, LH, FSH, and E2 are all going up. I think this might bc he's still taking tamox which I've seen studies CAN effect HpTa (just not as much as clomid I think).
My_Pitch, can you post ALL your blood work tests: test, LH, FSH, estradiol, T3/4 etc in chronological order from the beginning and list them test by test so we know what numbers were with what test and when? That could help out instead of having to keep going back and forth and seeing them all listed chronologically. I would also CEASE all medications/drugs not prescribed to you by your doctor well before your next upcoming test. You want an ACCURATE test result p, not one influenced by self-medication. Maybe even hold off on the levo (if your doctor agrees with this) to get everything accurate and baseline for where you're at now. Try to take the blood work at the same time of day as all your other tests too, you don't want numbers skewed bc some test are in the AM and maybe fasted while others are in a fed state late in the evening. One more thing, torem and letro I believe are better than raloxifene so after the blood test maybe try using them instead of ralox.
I'm going out on a limb here, but with LH levels like those, I bet your body thinks it's making too much testosterone and therefore is bumping up the aromatase - making more estrogen. Sorry man, but if it were me - I'd be on RUI's website right now snagging a bottle of stane to get that back down. A lot of doctors are scared of prescribing medication for off-label use (AI's are intended for women after all), which is probably why she is being so hesitant. Otherwise, you can hope that your levels normalize over time - which is probably what she's hoping for too.