Progesterone cream affecting E2 test results?

[Aleeri]

I have a question, I recently tested low on Progesterone and Cortisol and I started progesterone cream in 10mg a day before bed to get these up.

These are results before progesterone supplementation:

Cortisol (Serum) 6.6 ug/dL (10:18am) - Ref: 6.24-18 ug/dL
Progesterone 0.19 ng/mL - Ref: 0.3 ng/mL (Men age 18-29)

It improved issues with anxiety and helped me sleep a lot better. But now after 1 month I have retested E2 and it shows up as very low.

E2: < 10 pg/mL (before: 25)

I think I overdid the progesterone because my E2 doesn’t show up on the normal test (this is not sensitive test).

I think I screwed my E2 test up also because I took progesterone before bed day before test in morning. I also took more then usual because leak from bottle.

However I do not feel much symptoms of low E and I have felt ok. I had low E from AI use before and this is not same feeling. Obviously I am stopping progesterone now.

Anyone know if Progesterone cream 8-12 hours before E2 test can scew the test results lowering E2 to much?

 

[Milton]

Welcome to the boards! How low where your original test results?

 

[Aleeri]

Welcome to the boards! How low where your original test results?

Thanks Milton!

I have an original post here with a lot of labs:
steroidology.com/forum/men-general-health/684964-working-hcg-mono-therapy-but-no-libido-sex-drive.html

I figured I wanted to make a new thread here to discuss Progesterone more and not my previous low T which I have managed to improve.

 

[Milton]

Thanks Milton!

I have an original post here with a lot of labs:
steroidology.com/forum/men-general-health/684964-working-hcg-mono-therapy-but-no-libido-sex-drive.html

I figured I wanted to make a new thread here to discuss Progesterone more and not my previous low T which I have managed to improve.

Thanks for this help is on its way.

 

[halfwit]

I am having a tough time understanding why on earth you would take progesterone in the first place. Sure, if it's extremely low, you can treat it - but that's by looking at he adrenals (your cortisol points in that direction too), not taking the actual hormone that definitely can crush other hormones. We're not like women; we introduce a hormone, and it can turn everything completely off.

To answer your question, yes progesterone can suppress estradiol, but your testosterone would also change dramatically. I wonder if this is due to the Fadogia Agrestis, which is known to interfere with testicular chemistry and the feedback loop (estradiol comes into play here). It's just strange to me to see (in your other thread) such a radical difference between test and estradiol while your LH/FSH hardly budge.

I'd definitely stop with the cream.