RUI's UDCA
- Thread starter Platinum-
- Start date
livingwithdoms
New member
yea all you need is two caps per week and that should be fine.
tballz
New member
That's exactly how I dosed it. 1 cap Monday and 1 cap Thursday.
lol !!
Its a form of liver protection agent from RUI which is used to treat liver disease shit like yaundice (yellow eyes/skin).
Read more about it on RUI banner up top man. Its stronger then liv22 and milk thistle put togther. Lowers cholestrol also. Theres a bit about udca medical wise .... not a whole lot on the use with aas though. However those used it and with post blood test, results were great.
Its a form of liver protection agent from RUI which is used to treat liver disease shit like yaundice (yellow eyes/skin).
Read more about it on RUI banner up top man. Its stronger then liv22 and milk thistle put togther. Lowers cholestrol also. Theres a bit about udca medical wise .... not a whole lot on the use with aas though. However those used it and with post blood test, results were great.
tballz
New member
Yep...great stuff. Also dissolves gallstones.
freakinhuge
New member
rui's udca is very good liver support, 2 caps per week should be all you need.
Optimum dose of ursodeoxycholic acid in primary biliary cirrhosis.
Verma A, Jazrawi RP, Ahmed HA, Davis T, Bland JM, Benson M, Orchard RT, Theodossi A, Maxwell JD, Northfield TC.
Source
Division of Gastroenterology, Endocrinology and Metabolism, St George's Hospital Medical School, London, UK.
Abstract
BACKGROUND:
Ursodeoxycholic acid (UDCA) improves liver function tests and prolongs survival in primary biliary cirrhosis (PBC). The dose of 10- 15 mg/kg/day used in the large trials has largely been based on that used for gallstone dissolution. The only dose-response study of UDCA in PBC suggested that a dose of 8 mg/kg/day was the most efficacious. However, disease stage of the patients was not known, higher doses of UDCA were not tried and there was no 'washout period' between the different doses. The aim of this study was to determine the optimum dose of UDCA in early-stage PBC (stage 1 and 2).
METHODS:
Twenty-four biopsy-proven early-stage PBC patients (one male, 23 female) received five doses of UDCA (0, 300, 600, 900, 1200 mg/day) each for 8 weeks with 4-week washout periods between doses. Symptoms (pruritus, fatigue, diarrhoea) were assessed on a four-point scale (none, mild, moderate, severe). Liver function tests (LFTs) were performed using conventional methods, and serum bile acids were measured using gas liquid chromatography.
RESULTS:
The dose of 900 mg/day produced the greatest enrichment of UDCA in serum bile acids; although there was no difference in the enrichment of UDCA between the different doses. There was a trend towards normalization of the abnormal LFTs in a dose-dependent manner (for y-glutamyl transferase (yGT), alkaline phosphatase (ALP), alanine transaminase (ALT) and IgM). Multi-factorial analysis showed that UDCA treatment, irrespective of dose, was significantly better than placebo for all the variables. The 900 and 1200 mg doses were better than both 300 and 600 mg using yGT and total bilirubin as variables, better than 300 mg using ALP and IgM as variables, and better than 600 mg using albumin as a variable. No variables showed a significant difference between 900 and 1200 mg.
CONCLUSION:
The optimum dose of UDCA is 900 mg/day (equivalent to 13.5 mg/kg/day).
ncbi.nlm.nih.gov/pubmed/10524634
Verma A, Jazrawi RP, Ahmed HA, Davis T, Bland JM, Benson M, Orchard RT, Theodossi A, Maxwell JD, Northfield TC.
Source
Division of Gastroenterology, Endocrinology and Metabolism, St George's Hospital Medical School, London, UK.
Abstract
BACKGROUND:
Ursodeoxycholic acid (UDCA) improves liver function tests and prolongs survival in primary biliary cirrhosis (PBC). The dose of 10- 15 mg/kg/day used in the large trials has largely been based on that used for gallstone dissolution. The only dose-response study of UDCA in PBC suggested that a dose of 8 mg/kg/day was the most efficacious. However, disease stage of the patients was not known, higher doses of UDCA were not tried and there was no 'washout period' between the different doses. The aim of this study was to determine the optimum dose of UDCA in early-stage PBC (stage 1 and 2).
METHODS:
Twenty-four biopsy-proven early-stage PBC patients (one male, 23 female) received five doses of UDCA (0, 300, 600, 900, 1200 mg/day) each for 8 weeks with 4-week washout periods between doses. Symptoms (pruritus, fatigue, diarrhoea) were assessed on a four-point scale (none, mild, moderate, severe). Liver function tests (LFTs) were performed using conventional methods, and serum bile acids were measured using gas liquid chromatography.
RESULTS:
The dose of 900 mg/day produced the greatest enrichment of UDCA in serum bile acids; although there was no difference in the enrichment of UDCA between the different doses. There was a trend towards normalization of the abnormal LFTs in a dose-dependent manner (for y-glutamyl transferase (yGT), alkaline phosphatase (ALP), alanine transaminase (ALT) and IgM). Multi-factorial analysis showed that UDCA treatment, irrespective of dose, was significantly better than placebo for all the variables. The 900 and 1200 mg doses were better than both 300 and 600 mg using yGT and total bilirubin as variables, better than 300 mg using ALP and IgM as variables, and better than 600 mg using albumin as a variable. No variables showed a significant difference between 900 and 1200 mg.
CONCLUSION:
The optimum dose of UDCA is 900 mg/day (equivalent to 13.5 mg/kg/day).
ncbi.nlm.nih.gov/pubmed/10524634
kataklysum
New member
2 caps per week? That's 500mg a week. If your running an oral 2 caps a week won't really do much. There was a study done that showed they treat patients with trashed livers with 1g a day. If I'm running orals I normally run 1.5g a day
Similar threads
