Testosterone = More Muscle Fibers

[ManOfMuscle]

This thread makes me laugh, someone starts some hype for high doses then like lemmings everyone ups there doses, if I posted an artical on low doses everyone would suddenly cut there doses...just pointing out the obvious.

You had never heard that steroid effects were dose dependant?

 

[sean usmc]

i push 1,225 mg of test a week 375 mg.per shot 1cc 3xa week and really dont see much.I DO but nothing to write home about..should i drop it a bit or just the dose twice a week instead of 3 ..

 

[sean usmc]

matter of fact i am going to drop it to 750 mg a week i noticed better gain when i was on test 200.hmm wow thanks man awesome thread..

 

[Mudge]

You are 193 pounds and running all that shit?

 

[Lucky13]

Yeah sorry docj sounded like I was flaming, great article thx for posting I was just a bit shocked by everyone suddenly upping there doses in response to it.

 

[carolinacrackah]

Yeah sorry docj sounded like I was flaming, great article thx for posting I was just a bit shocked by everyone suddenly upping there doses in response to it.

Only upping my dose cause i've been cycling for years at no higher than 750mg test enathate per week. As already mentioned new users need to be carefull and understand that this is not recommended for newbies.

 

[Thoms]

I will up my dose when I feel it's necessary and no sooner. But if above is true, it would be a nice bonus.

 

[DocJ]

This is some exciting sh*t:
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J Physiol. 2006 Feb 1;570(Pt 3):611-27. Epub 2005 Dec 8.

Skeletal muscle hypertrophy and structure and function of skeletal muscle fibres in male body builders.D'Antona G, Lanfranconi F, Pellegrino MA, Brocca L, Adami R, Rossi R, Moro G, Miotti D, Canepari M, Bottinelli R.
Department of Experimental Medicine, Human Physiology unit, University of Pavia, Via Forlanini 6, 27100 Pavia, Italy. giuseppe.dantona@unipv.it

Needle biopsy samples were taken from vastus lateralis muscle (VL) of five male body builders (BB, age 27.4+/-0.93 years; mean+/-s.e.m.), who had being performing hypertrophic heavy resistance exercise (HHRE) for at least 2 years, and from five male active, but untrained control subjects (CTRL, age 29.9+/-2.01 years). The following determinations were performed: anatomical cross-sectional area and volume of the quadriceps and VL muscles in vivo by magnetic resonance imaging (MRI); myosin heavy chain isoform (MHC) distribution of the whole biopsy samples by SDS-PAGE; cross-sectional area (CSA), force (Po), specific force (Po/CSA) and maximum shortening velocity (Vo) of a large population (n=524) of single skinned muscle fibres classified on the basis of MHC isoform composition by SDS-PAGE; actin sliding velocity (Vf) on pure myosin isoforms by in vitro motility assays. In BB a preferential hypertrophy of fast and especially type 2X fibres was observed. The very large hypertrophy of VL in vivo could not be fully accounted for by single muscle fibre hypertrophy. CSA of VL in vivo was, in fact, 54% larger in BB than in CTRL, whereas mean fibre area was only 14% larger in BB than in CTRL. MHC isoform distribution was shifted towards 2X fibres in BB. Po/CSA was significantly lower in type 1 fibres from BB than in type 1 fibres from CTRL whereas both type 2A and type 2X fibres were significantly stronger in BB than in CTRL. Vo of type 1 fibres and Vf of myosin 1 were significantly lower in BB than in CTRL, whereas no difference was observed among fast fibres and myosin 2A. The findings indicate that skeletal muscle of BB was markedly adapted to HHRE through extreme hypertrophy, a shift towards the stronger and more powerful fibre types and an increase in specific force of muscle fibres. Such adaptations could not be fully accounted for by well known mechanisms of muscle plasticity, i.e. by the hypertrophy of single muscle fibre (quantitative mechanism) and by a regulation of contractile properties of muscle fibres based on MHC isoform content (qualitative mechanism). Two BB subjects took anabolic steroids and three BB subjects did not. The former BB differed from the latter BB mostly for the size of their muscles and muscle fibres.

PMID: 16339176 [PubMed - indexed for MEDLINE]

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What does all this mean? They're suggesting that the only way to explain the amount of muscle gained is that not only muscle hypertrophy occured but also muscle hyperplasia.

 

[simpllyhuge]

so can some one put this in laymens terms for me. my adderal isnt working right now and i cant read this thread.

also from looking at pictures i noticed that im always looking bloated when on higher amounts of test. shouldnt 25mg of aromasin a day totally stop this?

 

[DocJ]

so can some one put this in laymens terms for me. my adderal isnt working right now and i cant read this thread.

also from looking at pictures i noticed that im always looking bloated when on higher amounts of test. shouldnt 25mg of aromasin a day totally stop this?

Here's the two basic points:
1. Lower dose cycles may produce good results for many people but many will get the most bang for their buck withOUT increased sides at 300mg/week or slightly higher.
2. It's possible that gradually increasing your dose of test, it could contribute to more muscle fibers being formed.

25mg of aromasin per day should get rid of most of your bloat, however, depending on your dose it might not be possible to totally elimate all bloating.

 

[simpllyhuge]

ok thanks doc cj. what about stacking, does this also increase muscle fibers.

 

[DocJ]

ok thanks doc cj. what about stacking, does this also increase muscle fibers.

We just don't know that yet...the only research done now usually uses only one compound and it's almost always deca or test.

 

[Thoms]

We just don't know that yet...the only research done now usually uses only one compound and it's almost always deca or test.

Yeah...research on other steroids like tren or eq or scarce...since test and deca are still commonly used in HRT when the others are not...