The mystery of anadrol

[LoneWolfe]

This may be the one most valuable nugget of info yet, once confirmed. That is, if the gyno symptoms are progesterone related. Unfortunately there's no way of really know whether it's progesterone or estrogen related gyno when running Test with a progestin.

I'm not taking sides or trying to stir anything further, but nolva down regulates PGR is what Oak has been saying all along. Why are you only considering this as "the one most valuable nugget of info" now?

 

[JuiceAuthority]

I'm not taking sides or trying to stir anything further, but nolva down regulates PGR is what Oak has been saying all along. Why are you only considering this as "the one most valuable nugget of info" now?

Because that wasn't something I knew or had taking into consideration prior to posting this thread. As I stated in one of my earlier posts....

I honestly don't know. I stated what I know. Some say the reasoning drol produces these anabolic effects is through non-AR-mediated effects, but that doesn't quite make sense to me, and certainly doesn't explain why it causes gyno, or more importantly, what you can use to prevent it. If it's not estrogenic or progestogenic then there's no binding activity to the ER or PR.

I'm not trying to debate you; I'm really looking for facts I may not already know together other people's experience who may have dealt with similar issues using this particular combination of compounds (test, deca and drol).

Others felt it necessary to start debating with me in a confrontational way so I responded in like manner. I digressed and it turned into a pissing contest. That said there's a ton of useful information that resulted from all the banter that hopefully others benefited from as well. I know I did and I'm far beyond taking things personal online. OAK, Cashout, and RJ posted some good info and we all learned a little more as a result, flaming and name calling aside.

 

[JuiceAuthority]

wow I didnt know guys made estrogen? I thought we aromatised our testosterone to get estrogen...............................

Hey DEK - came across this on my homeboard today. The OP asked why some men naturally have too much estrogen. You'll like the response.

I was watching one of my wife's shows with her called shedding for the wedding, Im not claiming to be a greek god or anything but these guys on this show are some of the most feminine men I have ever seen! I have seen some chubby people in my time but these guys have real tits. Im talking like a c cup, and they are weaker then their wives. This one guy tried to climb a 6 foot wall. He took off in a dead sprint and jumped like 6 inches and just splatted against the wall. Then he went into a panic attack because he bumped his knee on the wall. He looked like he was having a stroke, Im serious his face couldnt move, he couldnt breath and his hand was locked up like he was having a seizure and he was saying am I going to die! Now im not one to make fun of people especially people with disabilities, but I couldnt help to wonder if these people would just benefit from a estrogen blocker.

Yes, in males the more adipose tissue (body fat) then the more aromatase enzyme which is found there in abundance. This enzyme is responsible for the process of converting testosterone to estrogen so if people carry a large amount of body fat they will have a less favourable test:estrogen balance in the latters favour. This increase in estrogen may then lead to an increase in retinoic acid-related orphan receptor-alpha or RORA which has a direct positive correlation with aromatse enzyme production. Basically as estrogen increases, RORA increases, aromatase enzyme production increases. This would then have a knock on effect over the negative feedback loop with estrogen being the dominant regulator of the Hypothalamus-Pituitary-Testicular-Axis (HPTA) leading to a reduction in androgen production.

Estrogen has many beneficial functions, even in males, but when levels rise outside of what is classed as normal or the ratio between androgens and estrogen is thrown out of balance then our general health can become a worry. Cardiovascular disease and gynecomastia are two of the more common problems.

 

[hardgainer08]

This board is no different then most. Where the vets are pen pals and stick together in flaming new members and never really answer the freakin question in a intelligent professional manner. Whether there wrong or right, No one has all the answers, but it would be nice to hear people's opinions/ thoughts and recommendations.

 

[glubgawd]

This board is no different then most. Where the vets are pen pals and stick together in flaming new members and never really answer the freakin question in a intelligent professional manner. Whether there wrong or right, No one has all the answers, but it would be nice to hear people's opinions/ thoughts and recommendations.

I have all the answers. Your ignorance will get you punished! You must be banned newbface!!

 

[hardgainer08]

lol ok I was just stating my opinion, no harm in that is there ?

 

[JuiceAuthority]

Well, the one big takeaway for me was Nolva down-regulates the PgR temporarily. All the banter back and forth, flaming and name calling was worth that one piece of info I didn't know. Now I can incorporate Nolva into my gyno prevention arsenal when running progestins.

 

[glubgawd]

lol ok I was just stating my opinion, no harm in that is there ?

was just messing with you man