What Are The Downsides To Test All The Time

[halfwit]

Interesting.. What will help connective tissue to grow so to avoid injury? HGH? Others?

As mentioned above, time and HGH. Proper stretching and warm-up exercises help tremendously as well, but the body still has to play catch-up.

So let me jump in and ask this question..... if myostatin is not the issue and AR downreg is a myth then what pray tell is causing this PERCEIVED stopping of gains on an extended cycle?
Is it not eating enough, losing intensity in the gym??

As lbm increases, so does TDEE. If caloric needs (obviously macro needs too) aren't met by adjusting - growth cannot occur. Myostatin is real, but we just don't fully understand the total picture yet.

It would be great if we could get these guys that do the studies to actually understand why data point determination is so critical, it would be fantastic. It would also help reduce any potential misunderstanding from the community in general as I know many of us do (myself included on many occasions) skim through, hoping that the conclusion/results are written in a meaningful way.

 

[.Vision.]

Well aside from the topic, it's not easy going pounding the and slamming the grind for 12-14 straight, I dont care who you are, its taxing on the body especially on hormonal level (first 6-8 weeks blasting is tits, tailoring the end I give more much need brakes to continue the momentum)
anyhow,

Myostatin is real, theres a ton of studies suggesting this or that, but even with moderate/low levels there is still a molecular changing through the genetic network..There's all sorts of stages and modes underling signaling with AR's (Im not saying AR down regulation because it does not exist)..however there is many switches taking place,the presence of AR antagonist and so on..Even some growth factors (TGF beta) can express a slew of issues by inhibiting the formation of NEW muscle growth.. upregulation of myostatin can take place at any given time,so many factors take place (Example) testosterone converting to DTH has been known to upregulate key myostain proteins..
E1 levels, even progens as they can posses a powerful antiadrogenis effect on some...So much many things can be taking place!

We truly lack a broad understanding of the effects of AAS and systhesis concerning hormones on molecular level, studies are always contradicting one an other as more and more are being conducted..

For myself an some others, I have better results incorporating an oral that's anti catabolic as it works with a entirely different targeting property outside of the AR's, working from a different mechanism..

Allow me reiterate here, Im not advocating that Myo is the issue, Im merely saying there is all sorts of factors under this whole spectrum!

 

[Mrrippedzilla]

I think something we can all agree on is that ARs, myostatin, etc are all part of a much larger system involved in inducing muscle growth.
Its a mistake to focus & isolate just 1 part of this system.

If you've stopped growing here are 3 practical steps to solve the issue:
1 - Sort out your diet according to your new TDEE.
2 - Make sure your progressing in the gym in a structured manner.
3 - Up the dose brah

 

[.Vision.]

Myostatin is real, but we just don't fully understand the total picture yet.

.

Brother, you stole the words right outa my mouth as I was writing this..We truly lack a broad understanding of the effects of AAS and systhesis concerning hormones on molecular level, studies are always contradicting one an other as more and more are being conducted..

Despite popular use and abuse, we're just sctartching the service with hormones on molecular level

 

[.Vision.]

i think something we can all agree on is that ars, myostatin, etc are all part of a much larger system involved in inducing muscle growth.
Its a mistake to focus & isolate just 1 part of this system.

if you've stopped growing here are 3 practical steps to solve the issue:
1 - sort out your diet according to your new tdee.
2 - make sure your progressing in the gym in a structured manner.
3 - up the dose brah

bingo!

 

[Hypnotix]

Being in an enhanced state of nitrogen retention and anabolism does put some strain on the body. Assuming you're taking advantage of said state, the first thing that comes to mind is connective tissue strength. Unfortunately, AAS doesn't really help them grow, and in fact slows regeneration of such tissues over time.

This leads to injury over time, as eventually the muscles will become too strong for the "weak link" of said tissues. Probably the biggest problem we face outside the obvious androstenedione elevation bringing up blood pressure over time and hematocrit. HCT can be managed, but without pharmaceutical intervention, blood pressure is far more tricky.

What the time limit is for each of us is about set in stone as matching finger prints; just have to listen to our bodies, and do what we can to help keep things running imho.

My .02c

So, what makes connective tissues grow faster?

 

[cybrsage]

As lbm increases, so does TDEE. If caloric needs (obviously macro needs too) aren't met by adjusting - growth cannot occur. Myostatin is real, but we just don't fully understand the total picture yet.

This is what initially limited my gains - so 3J increased my clean bulk calorie content once, then later added a smart cheat day to increase it further. Each time my gains restarted. Like he said "you have to eat to grow, it is that simple".

 

[Megatron28]

This is what initially limited my gains - so 3J increased my clean bulk calorie content once, then later added a smart cheat day to increase it further. Each time my gains restarted. Like he said "you have to eat to grow, it is that simple".

" Smart Cheat Day". That's what we are calling it now? That's awesome! I love it.

 

[.Vision.]

This is what initially limited my gains - so 3J increased my clean bulk calorie content once, then later added a smart cheat day to increase it further. Each time my gains restarted. Like he said "you have to eat to grow, it is that simple".

A "system re-feed" is always good...when blasting in the summer this is why I look forward to BBQs at friends houses..

 

[halfwit]

so, what makes connective tissues grow faster?

hgh.

 

[.Vision.]

hgh.

there's always room for peps..GHrp-6.. get your eats up! lol

 

[cybrsage]

" Smart Cheat Day". That's what we are calling it now? That's awesome! I love it.

He said "eat what you like but don't be an idiot about it" or something like that.

 

[Hypnotix]

He said "eat what you like but don't be an idiot about it" or something like that.

So... eat a well balanced shitty meal. Like a huge greasy burger loaded down with veggies and fries! Been there with him actually. Got one a week when I was in my bulk.. sometimes it'd leak to the next meal too.. but damn was it always a relief and something I looked forward to.

One can only take so much extra peanut butter ;_)

 

[Hypnotix]

hgh.

I have had my eye on it for a good while now... Seems like a no brainer to be doing alongside TRT let alone every cycle. It's just pricey :/

 

[halfwit]

I have had my eye on it for a good while now... Seems like a no brainer to be doing alongside TRT let alone every cycle. It's just pricey :/

Yeah, there's a reason why it's something only the upper middle class and upper class have had exclusive rights to for some time. I do have a bud that was recently prescribed it, so I know it can be done - just gotta pay that crazy price.

Then again, if one has the means to afford literally the fountain of youth, I can hardly hold it against them either.