What is the fastest anyone has ever felt different from their first injection.

[Tornadoalley]

I just got my first TRT shot yesterday 100/ml cyp and I can already tell something is different. Probably because I am not in bed. I felt pretty crappy for years, and I knew something was up. I am just glad it was this and not cancer or something worse.

I have been to the gym twice, cleaned the house and I am about to do some graduate level homework. If I ever went to the gym before, I was done for the night. When I came home from work, I was so sore and tired that I laid in bed. ALL NIGHT! I feel great, I feel like doing push ups!!! WAHOOOO

I understand alot of this may be in my head, but I have to say.... I feel better on day 2.

My levels were at 135 so... It is possible.

 

[Jimstigator]

I felt mine the next day. Placebo or not - it doesn't matter. I did a number of things the day after that I hadn't done in ages

Have fun.

-Jim

 

[hardpr]

happy for you both. but trust me its placebo. the mind is a powerful thing

 

[babyface58]

Congrats man I had the same experience with my first shot... Probably because your natural levels aren't shit down yet. Keep us updated on how it goes.

 

[Gossamer]

My test level prior to trt was 170. I got my first injection(200mg) on a Tuesday. On Wednesday I felt great. Went from having no energy, to having plenty of energy to work out and do yard work. And this was in the middle of a Florida summer. I know it wasn't a placebo.

On the downside, on the second day after my first injection, anxiety hit me like a Mack truck. Thankfully, with the help of members here, and other forums, I knew about aromatase. As bad as the anxiety was, I knew it would probably go away the next day. So I went to bed early, and woke up feeling great.

Just because some people don't feel effects the next day, that doesn't mean you won't. Everyone reacts their own way.

 

[tbonexl]

Cyp usually takes 3-6 weeks to fully hit the blood. Placebo is a mofo tho lol

 

[Virginian]

I had an effect a day after my first injection (400 mg test cyp). I didn't feel any different, but I went to the gym using my same weights as normal and was able to do higher reps than I had ever done for almost all of my exercises.

 

[Billegitimate]

Tornado: a couple things: first, testosterone Cypionate is usually formulated at 200mg of testosterone Cypionate per milliliter of liquid. Hence, 200mg/ml. I've seen you say things in various posts about 200/ml and 100/ml and even 160/ml. None of that makes any sense. Your doc isn't going to adjust the testosterone per milliliter for you.

So, the injectabLe testosterone has a strength, typically 200mg/ml, and then you take an amount of that. If you injected 1ml of that, you'd get 200mg of testosterone Cypionate. A 2ml injection gets you 400mg, a half ml gets you 100mg. So figure out what all that means, and quit saying these weird unit less things like 100/ml as you did in the first post of this thread.

I assume what happened was you got a 1/2ml injection and thus 100mg of testosterone Cypionate.

Now, as to feeling it, do some research on half life of test Cypionate. Different sources provide different numbers, but even if it's around 10 days, you're absorbing about 7% daily. So, 7mg of testosterone Cypionate in that first 24 hours. That's close to what a healthy young man produces (even taking ester weight into account guys) so to ascribe that to placebo is silly.

Especially with how low you were, a sudden introduction of even 4-5 mg actual testosterone would be Very noticeable.

Welcome to the club. Stay, learn all you can, and health can be the reward.

 

[Tornadoalley]

Tornado: a couple things: first, testosterone Cypionate is usually formulated at 200mg of testosterone Cypionate per milliliter of liquid. Hence, 200mg/ml. I've seen you say things in various posts about 200/ml and 100/ml and even 160/ml. None of that makes any sense. Your doc isn't going to adjust the testosterone per milliliter for you.

So, the injectabLe testosterone has a strength, typically 200mg/ml, and then you take an amount of that. If you injected 1ml of that, you'd get 200mg of testosterone Cypionate. A 2ml injection gets you 400mg, a half ml gets you 100mg. So figure out what all that means, and quit saying these weird unit less things like 100/ml as you did in the first post of this thread.

I assume what happened was you got a 1/2ml injection and thus 100mg of testosterone Cypionate.

Now, as to feeling it, do some research on half life of test Cypionate. Different sources provide different numbers, but even if it's around 10 days, you're absorbing about 7% daily. So, 7mg of testosterone Cypionate in that first 24 hours. That's close to what a healthy young man produces (even taking ester weight into account guys) so to ascribe that to placebo is silly.

Especially with how low you were, a sudden introduction of even 4-5 mg actual testosterone would be Very noticeable.

Welcome to the club. Stay, learn all you can, and health can be the reward.

So dont say things like .2g/.001L I will make sure to add the MG and ML from now on.
I got a one ml shot with 200mg. That 7% info is golden, and I have seen some different reports, but I do feel something. You may be the guy to ask this next question.

I did a cycle a year ago of test prop @ 100mg/ml EOD and I ran it for ten weeks. I did no post therapy or anything, and I am wondering if I did this to myself?

 

[Want2lift]

Wow, some good posts to chuckle at in this thread. Just goes to show you how much your mind can be a tool or your worst enemy. Trust me, nobody is getting strength gains over night from a shot of long estered test.

Remember, the mind is a beautiful servant but a terrible master.

 

[Billegitimate]

So dont say things like .2g/.001L I will make sure to add the MG and ML from now on.

I believe you're missing my point. state what you have injected, not the strength of what you injected.

It's like someone asking you how far you had to drive, and you tell them you drove at 50 mph. Well, that combined with the time you drove would answer the question, but a simple answer as to distance is easier than rate and time.

So if you're going to say you injected something, you can either give us the strength and the units injected: "I injected .5ml of 200mg/ml testosterone cypionate" or just do the math for us: "I injected 100mg of testosterone cypionate."

But saying "I just got my first TRT shot yesterday 100/ml cyp" doesn't mean anything. I don't know how big your shot was (100ml?) I don't know the strength of what you took, we can't figure out anything from that.

 

[tbonexl]

Yea that prop cycle with no pct could've done u in...

 

[Tornadoalley]

It was cyponate sorry. I don't know how I missed that.

 

[Tornadoalley]

Wow, some good posts to chuckle at in this thread. Just goes to show you how much your mind can be a tool or your worst enemy. Trust me, nobody is getting strength gains over night from a shot of long estered test.

Remember, the mind is a beautiful servant but a terrible master.

No strength gains at all. I am actually the weakest I have ever been, but I got through we day without beer bonging redbull today and that is unusual. I didn't even get a caffine headache. Great success !

 

[halfwit]

Tornado: a couple things: first, testosterone Cypionate is usually formulated at 200mg of testosterone Cypionate per milliliter of liquid. Hence, 200mg/ml. I've seen you say things in various posts about 200/ml and 100/ml and even 160/ml. None of that makes any sense. Your doc isn't going to adjust the testosterone per milliliter for you.

So, the injectabLe testosterone has a strength, typically 200mg/ml, and then you take an amount of that. If you injected 1ml of that, you'd get 200mg of testosterone Cypionate. A 2ml injection gets you 400mg, a half ml gets you 100mg. So figure out what all that means, and quit saying these weird unit less things like 100/ml as you did in the first post of this thread.

I assume what happened was you got a 1/2ml injection and thus 100mg of testosterone Cypionate.

Now, as to feeling it, do some research on half life of test Cypionate. Different sources provide different numbers, but even if it's around 10 days, you're absorbing about 7% daily. So, 7mg of testosterone Cypionate in that first 24 hours. That's close to what a healthy young man produces (even taking ester weight into account guys) so to ascribe that to placebo is silly.

Especially with how low you were, a sudden introduction of even 4-5 mg actual testosterone would be Very noticeable.

Welcome to the club. Stay, learn all you can, and health can be the reward.

Except it doesn't work that way. There isn't a set logarithmic decay translating mg of exogenous testosterone into ng/dl of blood concentration values.

While I like the facts posted, it's not accurate to state one injection provides 7% of the net value of hormone. Your body doesn't even see a fraction of the hormone injected as it first must cleave the ester before it can become biologically active.

Yes, placebo is one hell of a powerful force.

 

[Billegitimate]

So dont say things like .2g/.001L I will make sure to add the MG and ML from now on.
I got a one ml shot with 200mg. That 7% info is golden, and I have seen some different reports, but I do feel something. You may be the guy to ask this next question.

I did a cycle a year ago of test prop @ 100mg/ml EOD and I ran it for ten weeks. I did no post therapy or anything, and I am wondering if I did this to myself?

You're doing it again! You say you took prop @ 100mg/ml EOD. What? How much of the 100mg/ml prop did you take EOD?

It's like telling someone you took 80 proof whiskey every day, and asking them if that could that destroy your liver. Well, a quart of 80 proof whiskey a day would, a drop wouldn't. The quart and the drop are both 80 proof!

A ml of 100mg/ml test is 100mg/ml and 10ml of 100mg/ml is also 100mg/ml. It says nothing to the quantity you took!

In any case, it probably doesn't matter. If you didn't get multiple labwork done prior to, then after the post cycle therapy, you have no way of knowing. Regardless, unless you're going to go for a restart, time to ride a new horse.

TRT can be a good thing, but you have to educate yourself deeply on it. Dive in and read and think, and in no time at all you'll realize you know more than 99% of the docs out there prescribing the stuff.

 

[Billegitimate]

Except it doesn't work that way. There isn't a set logarithmic decay translating mg of exogenous testosterone into ng/dl of blood concentration values.

While I like the facts posted, it's not accurate to state one injection provides 7% of the net value of hormone. Your body doesn't even see a fraction of the hormone injected as it first must cleave the ester before it can become biologically active.

Yes, placebo is one hell of a powerful force.

It isn't quite that simple, but the half life is defined. The rate at which your body is absorbing the drug from the depot to blood stream is an aspect of that half life. My 7% number is a rough swag based on a 10 day halflife. With a 10 day halflife, you're absorbing about 7% of whatever you have in your body at that point.

I didn't claim you could derive blood levels from this "decay" rate as you put it, but the decay rate itself is a simple logarithmic function. Can you explain how the half life would operate otherwise? It is a logarithmic decay already, since a half life is that to begin with. It's arbitrary to pick the half-life point as the point of measurement for the rate though.

I can say that something will be half absorbed in 10 days, then that half will be half absorbed in another 10 days, or I can define a daily rate of decay. For ten days, a 7% absorption, or 93% not absorbed is almost the same curve as a 10 day half life. .93 ^ 10 = .484, so after ten days it's decayed to 48.4% of original. Close enough.

I am open to your points though, perhaps you could describe how it is absorbed differently?

No one would argue that TNE isn't totally absorbed in a day. (Hours actually) And most will acknowledge that test prop hits them quite differently. Claiming that 7% of a test cyp injection is absorbed in the first 24 hours doesn't seem very outlandish. In someone with serum levels below 200, that will be enough to make a difference.

And a bit of reading on how testosterone not only changes muscles over time but also directly affects the ability to recruit muscle fiber in the moment (the entire reason people shoot test no ester just before a workout!) doesn't leave me shocked that someone that low would feel immediately stronger.

Not ruling out a placebo contribution, but ruling out the T for the reasons above doesn't seem appropriate.

 

[halfwit]

You are absolutely correct in that the hormone combined with the ester has a half-life (most use 8 days for calculations), and I do agree that the average person will metabolize said drug at a fairly predictable manner. In fact, I posted some spreadsheets awhile ago using injection frequencies to determine the approximate ebb and flow of blood volume concentrations.

I am not disputing the fact that there does exist a simple logarithmic function in which we can approximate the total mass of the hormone after a specific time frame. What I am disputing is that the metabolic process in which we are able to process the depot and actually make it biologically active is not so simple.

There are many factors ranging from the condition of the CYP3A4 chain (essentially elimination pathway), a person's diet (this can affect absorption and elimination), value of SHBG (free testosterone is what we receive the actual benefits from), the mass of a person (if blood volume is greater, it will require more drug to reach the same concentration per volume), the location of the depot (areas poor in blood circulation will see a slower release of hormone), the ester involved (yes, TNE has a half-life of about 4 hours), and many other factors that modern science still is discovering.

If we were able to receive the same amount of hormones from one injection that a healthy male produces from day one, how do we address the fact that testosterone cypionate (and roughly enanthate) has a peak time of about 48 hours? Furthermore, steady state values require several half-lives (roughly 3.5-4), which is often when a person is able to quantify measurable differences.

*I am on my phone, so I'm lacking bookmarks to back up these statements from medscape/pubmed/journal of endocrinology. I'll try to dig up my resources when I have a chance to hop on my desktop, so you know I'm not just pulling numbers from my ass. *

So while I acknowledge that there is SOME hormone in the bloodstream, and that there are even studies indicating a tripling of testosterone at the 48-72 hour mark post-injection, the odds of someone seeing eugonadal values within that time frame are very low. Unless we're talking ester-less testosterone as mentioned above of course.

I'll try to bring more facts to this tomorrow if still interested as I am getting the evil eye from the warden.. Er, my wife - as it's bedtime.

 

[Alpin]

Wow what long posts.

 

[RR88]

Gossamer and the others saying they felt the next day. No you didn't lol. And no, not everyone is different to that degree. Certain things hit quicker such as libido but your not feeling it like you think minimum 2 weeks. Don't say those things cause it's ridiculous and mis informs others that are new.