TheDarkHalf
NTBM Rep
So i'm sitting here half stuffed up and feeling run down....any of you all got a remedy that you use at the onset to kick out a cold before it sets in?
Zinc study - shortens duration of cold when taken in first 24 hours.
Efficacy of zinc against common cold vi - PubMed Mobile
Efficacy of zinc against common cold viruses: an overview.
Authors
Hulisz D.
Journal
J Am Pharm Assoc (2003). 2004 Sep-Oct;44(5):594-603.
Affiliation
School of Medicine, Case Western Reserve University, Cleveland, Ohio, USA. dth4@cwru.edu
Abstract
OBJECTIVE: To review the laboratory and clinical evidence of the medicinal value of zinc for the treatment of the common cold.
DATA SOURCES: Published articles identified through Medline (1980-2003) using the search terms zinc, rhinovirus, and other pertinent subject headings. Additional sources were identified from the bibliographies of the retrieved articles.
STUDY SELECTION: By the author.
DATA EXTRACTION: By the author.
DATA SYNTHESIS: Human rhinoviruses, by attaching to the nasal epithelium via the intracellular adhesion molecule-1 (ICAM-1) receptor, cause most colds. Ionic zinc, based on its electrical charge, also has an affinity for ICAM-1 receptor sites and may exert an antiviral effect by attaching to the ICAM-1 receptors in the rhinovirus structure and nasal epithelial cells. Clinical tests of zinc for treatment of common colds have been inconsistent, primarily because of study design, blinding, and lozenge contents. Early formulations of lozenges also were unpalatable. In three trials with similar study designs, methodologies, and efficacy assessments, zinc effectively and significantly shortened the duration of the common cold when it was administered within 24 hours of the onset of symptoms. Recent reports of trials with zinc gluconate administered as a nasal gel have supported these findings; in addition, they have shown that treatment with zinc nasal gel is effective in reducing the duration and severity of common cold symptoms in patients with established illness.
CONCLUSION: Clinical trial data support the value of zinc in reducing the duration and severity of symptoms of the common cold when administered within 24 hours of the onset of common cold symptoms. Additional clinical and laboratory evaluations are warranted to further define the role of ionic zinc for the prevention and treatment of the common cold and to elucidate the biochemical mechanisms through which zinc exerts its symptom-relieving effects.
PMID 15496046 [PubMed - indexed for MEDLINE]
When I get a cold I do what gunner does. I drink water til the pointi dint think I can drink anymore, then I drink a bunch more. Also take an extra muti, since I'm drinking so much water. Also use Zicam when I notice I'm first getting sick. A few sprays of that stuff every three hours or so. Works best when you use it early. This goes along with what Megatron was saying because I think the main benefit of the Zicam is the zinc that is in it.
The kind that used as zincum aceticum and directions say to spray into roof of mouth and or on gums. So I think/hope this one is okay.In 2009, the U.S. Food and Drug Administration (FDA) advised consumers to avoid intranasal versions of Zicam Cold Remedy because of a risk of damage to the sense of smell, leading the manufacturer to withdraw these versions from the U.S. market.[4] The Zicam brand has been expanded to include non-zinc formulations.