So this is not attack your friends protocol day. Let's keep things civil. There is nothing wrong with discussion protocols or treatments. Lets remember the Dr are the one prescribing treatment.
Basically it says the BMD benefits of testosterone are not totally related to testosterone. That in order to fight off things like osteoporosis we need estrogen as well. One of the big problems of low-t is frailty.
In a nutshell, thats just one of the many reasons why having low estrogen for long periods of time can be problematic.
Only the combined treatment led to optimal parameters of aBMD suggesting that testosterone needs estrogens as a permissive factor for a direct androgen anabolic action on bone in men.
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