Albuterol or Thermorexin

I have use albuterol..here in spain is legal.we use it for "asma"...It better than clembuterol, because it is more specific with beta receptors...If you uese albuterol use ketotifeno o clean the receptors at night..
 
YOMISMICO said:
I have use albuterol..here in spain is legal.we use it for "asma"...It better than clembuterol, because it is more specific with beta receptors...If you uese albuterol use ketotifeno o clean the receptors at night..

I wouldn't jump to that conclusion. I know of at least two people that noticed very little from albuterol and lots from clen, while others noticed thought clen was okay and albuterol was amazing. I would say try both eventually and decide for yourself.

Though it's pretty widely accepted that clen can cause heart damage, i haven't seen anything on albuterol...now I wouldn't take that as saying it's 100% safe, but it's a consideration.

As for Thermorexin, I dont really buy any supps I don't need from the store. Most of them do jack squat and if they do work, the cost vs. results is not worth it. Many people have prepared for comps and came in absolutely shredded without the use of any fat burners...
 
Perfection Awaits said:
why...is 2 weeks the max u should stay on albuterol?

You could stay on albuterol longer. I just feel it would prolong the effectiveness of it by alternating every two weeks. It's what I do with clen/ECA and it works really well.
 
There are some benefits of albuterol over clen:
1. You can use it longer.
2. It raises HDL.
3. Increases in lean muscle mass were seen in studies.
 
DocJ said:
There are some benefits of albuterol over clen:
1. You can use it longer.
2. It raises HDL.
3. Increases in lean muscle mass were seen in studies.


Doc, do you know of any heart studies done with albuterol? I'm under the impression it's fairly new, so I dunno if anything's been done yet.
 
outlawtas2 said:
Doc, do you know of any heart studies done with albuterol? I'm under the impression it's fairly new, so I dunno if anything's been done yet.
Most studies showing cardiac problems were on patients who already had heart problems and the albuterol made them worse (big suprise). I did find this though, again like with the clen studies all done on rats:

Arch Toxicol. 1994;68(4):213-6.
A review of the toxicology of salbutamol (albuterol).Libretto SE.
Pathology and Toxicology Division, Glaxo Group Research Ltd., Ware, Hertfordshire, United Kingdom.

This paper reviews the published toxicology of salbutamol. Salbutamol is a relatively selective beta 2-adrenoreceptor stimulant with rapid, potent bronchodilator activity and only minor inotropic or chronotropic effects. It was not found to be mutagenic. LD50 values and other acute studies indicated low toxicity. Findings published for repeat dose studies were mainly uneventful. Tachycardia and flushing of the skin were observed in dogs. There were several findings peculiar to the rat--growth of the salivary gland, enlargement of the Harderian gland, an increase in colloid in the pituitary, and mesovarian leiomyomas. Increases in heart weights associated with inflammation, hypertrophy of muscle fibres, focal myocardial necrosis and fibrosis were seen in rats. Malformation, in the form of cleft palate, was reported in mice but not in rats or rabbits. These treatment related effects reported for salbutamol are not compound-related but rather are class-related. They are an expression of pharmacological activity brought about by the excessive beta stimulant action of high dosage with the drug.

PMID: 8067892 [PubMed - indexed for MEDLINE]

----------------------------------------------------
Here's one on muscle hypertrophy:
Br J Pharmacol. 2006 Mar;147(6):587-95.
Systemic administration of beta2-adrenoceptor agonists, formoterol and salmeterol, elicit skeletal muscle hypertrophy in rats at micromolar doses.Ryall JG, Sillence MN, Lynch GS.
Basic and Clinical Myology Laboratory, Department of Physiology, The University of Melbourne, Grattan Street, Victoria 3010, Australia.

beta(2)-Adrenoceptor agonists provide a potential therapy for muscle wasting and weakness, but their use may be limited by adverse effects on the heart, mediated in part, by beta(1)-adrenoceptor activation. Two beta(2)-agonists, formoterol and salmeterol, are approved for treating asthma and have an extended duration of action and increased safety, associated with greater beta(2)-adrenoceptor selectivity. The pharmacological profiles of formoterol and salmeterol and their effects on skeletal and cardiac muscle mass were investigated in 12-week-old, male F344 rats. Formoterol and salmeterol were each administered via daily i.p. injection at one of seven doses (ranging from 1 to 2,000 microg kg(-1) day(-1)), for 4 weeks. Rats were anaesthetised and the EDL and soleus muscles and the heart were excised and weighed. Dose-response curves were constructed based on skeletal and cardiac muscle hypertrophy. Formoterol was more potent than salmeterol, with a significantly lower ED(50) in EDL muscles (1 and 130 microg kg(-1) day(-1), P <0.05), whereas salmeterol had greater intrinsic activity than formoterol in both EDL and soleus muscles (12% greater hypertrophy than formoterol). The drugs had similar potency and intrinsic activity in the heart, with a smaller leftward shift for formoterol than seen in skeletal muscle. A dose of 25 microg kg(-1) day(-1) of formoterol elicited greater EDL and soleus hypertrophy than salmeterol, but resulted in similar beta-adrenoceptor downregulation. These results show that doses as low as 1 microg kg(-1) day(-1) of formoterol can elicit significant muscle hypertrophy with minimal cardiac hypertrophy and provide important information regarding the potential therapeutic use of formoterol and salmeterol for muscle wasting.

PMID: 16432501 [PubMed - indexed for MEDLINE]
 
thermorexin is as or more effective than clenbuterol or albuterol. IMH, but biased, O.

the beta agonist cardiac apoptosis that applied to clenbuterol also applies to albuterol. In people that respond well to beta 2 adrenergic stimulation they are good fat burners, though typically there is massive down regulation after 2-3 weeks of use and repeated use are often significantly less effective even with long breaks.

reccomend EC over either clen or albuterol.
 
macro said:
reccomend EC over either clen or albuterol.
Just realized I never answered the original question....I agree with Macro on this, EC is more useful over the long term.
 
Perfection Awaits said:
what the hell is EC? effy and caffine?
Yep.


Here is a question to go along....

Yohimbine....

Is there an optimal time to take it? It is fine to take it with your Ephedra and Caffeine?

I have always thought to take them all together, but I think I may have read a post a while ago saying not too. I don't remember the reason why, so I am asking in here.
 
Easto said:
Yep.


Here is a question to go along....

Yohimbine....

Is there an optimal time to take it? It is fine to take it with your Ephedra and Caffeine?

I have always thought to take them all together, but I think I may have read a post a while ago saying not too. I don't remember the reason why, so I am asking in here.
Blood pressure...some people have problems with it getting too high with that combo. During the day I take it together and don't have any problems but if I take that combo before I workout, I have problems.
 
Back
Top