You must apply the cardispan once per week or two maximum depending on the quantity of exercise you do, the best thing is using this product with cardiovascular and abs if it is the region in which you apply it, the correct way of putting it is to mix it with one g of xylocaine because if you do not do it hurts badly. You must use a small syringe ultra fine and apply measures of 1 ml in different areas. You do this cleaning the area to inject with alcohol, crush the skin or fat and injecting it subcutaneous. Do not abuse of the product and it is not miraculous you must do exercise and you will obtain good results an lean musle. I hope this information helps you. On having injected you must avoid veins because ir could damage some organs.