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Everyone has heard of it. Everyone knows what it's used for. Everyone knows how popular it is. In fact Cialis is rapidly becoming the most popular PDE5 inhibitor available.
So what is PDE5 and what does inhibiting it do? PDE5 is phosphodiesterase type 5. It is an enzyme that causes constriction of blood vessels. A PDE5 inhibitor like Cialis blocks this action is smooth muscle cells like those lining blood vessels. This causes dilation of those blood vessels and increase blood flow to the extremities. This causes a reduction in Blood pressure and to attempt offset that there is constriction of the blood vessels leading back to the heart. This causes increased blood flow and decreased return. The end result is well established.
The thing that separates Cialis from the other PDE5 inhibitors is its long active life. Cialis is active and elicits its effects for up to 36 hrs with one dose. Also mg /mg Cialis is more powerful than its predecessor and counterpart Viagra. Also many report less pronounced side effects using Cialis.
All in all it's easy to see why Cia is so popular as a PDE5 inhibitor. Its long active life and therefore lenient dosing requirements as far as timeframe go, make it a fantastic addition to our research arsenal.
Also of note, the combination of pt-141 and Cialis is proving ASTOUNDING research results. Results worth investigating.
Here it is >> Liquid Cia 30mL 30mg/mL
Refs
* Weiss, B. and Hait, W.N.: Selective cyclic nucleotide phosphodiesterase inhibitors as potential therapeutic agents. Ann. Rev. Pharmacol. Toxicol. 17:441-477, 1977
* Revill, Jo (February 2, 2003). "Drugs giant says its new pill will pack more punch than rival Viagra". The Observer. Retrieved 2007-04-06.
* Loyd, Linda (July 6, 2003). "Two Pills Look to Topple Viagra's Reign in Market; Levitra Expects Approval Next Month, Cialis Later This Year". The Philadelphia Inquirer
So what is PDE5 and what does inhibiting it do? PDE5 is phosphodiesterase type 5. It is an enzyme that causes constriction of blood vessels. A PDE5 inhibitor like Cialis blocks this action is smooth muscle cells like those lining blood vessels. This causes dilation of those blood vessels and increase blood flow to the extremities. This causes a reduction in Blood pressure and to attempt offset that there is constriction of the blood vessels leading back to the heart. This causes increased blood flow and decreased return. The end result is well established.
The thing that separates Cialis from the other PDE5 inhibitors is its long active life. Cialis is active and elicits its effects for up to 36 hrs with one dose. Also mg /mg Cialis is more powerful than its predecessor and counterpart Viagra. Also many report less pronounced side effects using Cialis.
All in all it's easy to see why Cia is so popular as a PDE5 inhibitor. Its long active life and therefore lenient dosing requirements as far as timeframe go, make it a fantastic addition to our research arsenal.
Also of note, the combination of pt-141 and Cialis is proving ASTOUNDING research results. Results worth investigating.
Here it is >> Liquid Cia 30mL 30mg/mL
Refs
* Weiss, B. and Hait, W.N.: Selective cyclic nucleotide phosphodiesterase inhibitors as potential therapeutic agents. Ann. Rev. Pharmacol. Toxicol. 17:441-477, 1977
* Revill, Jo (February 2, 2003). "Drugs giant says its new pill will pack more punch than rival Viagra". The Observer. Retrieved 2007-04-06.
* Loyd, Linda (July 6, 2003). "Two Pills Look to Topple Viagra's Reign in Market; Levitra Expects Approval Next Month, Cialis Later This Year". The Philadelphia Inquirer
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