That's the short answer.
This is definitely my area of info if you really would love to know more though, so any questions ask away.
You mentioned specifically Adderall, which if you don't already know is straight amphetamine (75% dextroamp/25% levoamp amphetamine isomers), Dexedrine is just pure dextro-amphetamine aka D-Amphetamine the one with the most CNS efffects, least peripheral in effects and vice versa for the levoamp isomer.
Amphetamines are far harsher, stronger, potent, and physically taxing than caffeine, or any other stim except maybe Cocaine/MDMA but they are illicit drugs, Adderall while having heavy abuse potential is prescription and used by many people daily.
Amphetamines will burn you out and cause your body to get a workout in a way that isn't ideal in that it is literally forcing your body into a constant state of fight or flight mode. It achieves this mainly via releasing stored Norepinephrine and Dopamine in the reward centre of the brain creating a state of hyper awareness and energy, if dose is enough it will cause euphoria/sense of well-being/elevated mood (dopamine release above what can be achieved naturally causes a neurotoxic effect, especially higher the dose and longer the use, methamphetamine is far worse in this department), appetite supression and increased metabolism also result.
Doing cardio or any workout on a low dose 10-20mg max for me with Cialis (for BP) I find to be perfect but I do not go all out and it definitely has potential to be fatal in combo with AAS, but only for increased endurance or on a day you really need it if you don't take it daily if that's how your prescribed, it isn't ideal for your heart and it absolutely is better to do it without. IF you must and are prescribed amphetamines please try keep to the lowest dose and if your using AAS absolutely keep an eye on BP, some Cialis ED with the Adderall WILL help. It does for me whenever I use D-Amp. I don't mix it with any other stimulants either.