Finally! My "comprehensive" Pre-TRT Lab Results. Plz Advise

Flystar

New member
-Hormones

Testosterone, total
216 (286 - 802) ng/dL

Testosterone, free
34.17 (34.51 - 107.78) pg/mL

Testosterone, bioavailable
138 (138 - 430) ng/dL

SHBG
16.0 (14.5 - 48.4) nmol/L

E2 (Estrogen)
32.6 (7.6 - 43.0) pg/mL

LH
4.0 (1.7 - 8.6) mIU/mL

FSH
3.5 (1.5 - 12.4) mIU/mL

Prolactin
16.7 (3.46 - 19.4) ng/mL

Cortisol (AM) (had sex a little less than 48 hours prior to testing)
8.30 (3.7 - 19.4) ug/dL

IGF-1
160.3 (150 - 350) ng/mL

-Thyroid Panel

TSH
4.54 (0.27 - 4.20) uIU/mL

T3, free
3.6 (2.0 - 4.4) pg/mL

T4, free
1.24 (0.93 - 1.70) ng/dL

-Lipid panel

Cholesterol
216.1 mg/dL

Desirable: <200
Borderline: 200 - 239
High risk: >240

HDL
32.7 mg/dL

Low: <130
High: >60

LDL
139.5 (<130) mg/dL

VLDL
27.90 (<40.0) mg/dL

Tg (Triglyceride)
219.5 (<200) mg/dL

-CBC

HB (Hemoglobin)
12.5 (14 - 18) g/dL

Hematocrit
45.1 (42 - 50) %

RBC
4.79 (4.5 - 6.2) x10*6/uL

WBC
5.60 (5.0 - 10.0) x10*3/uL

WBC & diff / Lymphocyte
40.6 (20 - 40) %

MCH
26.0 (27 - 31) pg

MCHC
29.5 (32 - 36) g/dL

MCV
94.2 (80 - 95) fL

RDW
10.1 (2 - 20) %

Platelet count
250.0 (150 - 400) x10_3/uL

ESR
(up to 10) mm/hr

Clotting time
(2 - 6) mins

Bleeding time
(1 - 6) mins

-CMP

--General

Glucose (fasting)
98 (65 - 99) mg/dL

Calcium
8.60 (8.40 - 10.2) mg/dL

--Liver

ALP
82.0 (40 - 130) U/L

ALT (SGBT)
40.2 (Up to 41) U/L

AST (SGOT)
24.9 (Up to 40) U/L

Bilirubin, total
0.80 (up to 1.1) mg/dL

Bilirubin, direct
0.20 (up to 0.25) mg/dL

Bilirubin, indirect
0.60 (0.1 - 0.75) mg/dL

--Kidney

Urea Nitrogen (BUN)
43.5 (<50) mg/dL

Creatinine
0.862 (<1.1) mg/dL

--Electrolytes

Potassium
4.60 (3.60 - 5.5) mmol/L

Sodium
141.0 (135.0 - 152.0) mmol/L

Chloride
99.0 (98.0 - 110.0) mmol/L

--Proteins

Albumin
4.40 (3.6 - 4.6) g/dL

Protein, total
7.30 (6.4 - 8.3) g/dL

=============================================================

-Why I'm here:

1) Interested in starting TRT due to very low testosterone. Looking for advice.
2) Concern about my thyroid... Will it will cause problems later on if I start normal TRT protocol without doing anything about my thyroid issue (is it an issue?)?

-Stats:
Age: 33
Height: 6'5
Weight: 264 lb
Body fat: %27
Waist: 44"

-Body and facial hair:
Got a full on beard and mustache. If i shave now, 3 weeks later i would have a thick, combable beard and mustache.

Body hair I would say is "normal". I got hair on legs and arms and chest but nothing major, just fair amount I guess.

-Fat distribution:
I carry fat almost entirely on hips, thighs, buttocks and then belly.
Got a gut, now that I'm out of the gym. Something I never had when I was working out and dieting. The hips, thighs and buttocks fat have always been there though, although to a much lesser degree when I was working out...which was most of my life prior to 4 years ago (more on that in a little bit).

I was never able to "lean out" in those areas even at single digit body fat. That was extremely frustrating. Whenever I tried to shed fat, I would reach skeleton proportions everywhere else but those areas would still be far from lean.

-Medical history:
None.

Past 3 years...don't drink. Don't smoke.
Before that...smoked for 17 years. Drank for about 14 years or so but just during weekends and socially.

And yeah, no history of head trauma of any kind as far as I recall.

-Medication:
Propecia about 4 years ago.

Quit a few weeks in due to feeling completely lifeless downstairs. Things got back to normal shortly after I quit.

-Diet:
Used to be 6 meals a day, well thought out, strict, daily diet plans for most of my life until about 4 years ago when I started eating like the average American.

About %60 of my food is now fried. Every meal has white carbs. Drinking fruit juice all day.

-Training:
Now, zero.
4 years ago...a well though out, strict weight lifting regiment for 17 years.

Bodybuilding was my passion so I made sure I did everything correctly. I knew the harms of over training so I was sure not to over trained.

-What got me to suspect low testosterone (before getting blood work done):
a) Difficulty / inability to gain muscle.
b) Easily gain fat.
c) Almost all gained fat goes straight to hips, buttocks and thighs.
d) Almost %100 of IMS symptoms.
e) Loss of libido
f) Jewels shrinkage

-Thyroid:
Judging by my elevated TSH levels and normal fT3, I'm "subclinical" hypothyroidism. Basically I'm hypo since I'm higher than the already high TSH lab ranges. Thing is though, except for the weight issue, I got no symptoms of hypothyroidism. My thyroid situation concerns me before starting TRT. Waht would the harms be if I started TRT now? Will my thyroids be able to cope?

Body temp before sleep: 96.98 F
Body temp after wake up: 96.98 F
Body temp mid afternoon: 98 F (this was taken right after climbing a flight of stairs)

--Iodine intake:
I would say normal, but that's solely based on how much iodized salt I eat. I put more salt on my food than the average person. Always been like that since I was a kid. My food can be too salty for most people.

All the salt I eat is iodized, been that way since childhood so definitely had had long term use of iodized salt. Never seen any other salt around here anyway. Restaurants and pretty much everyone around here uses iodized table salt.

-A little history:
I started bodybuilding when i was 13. Seriously when I was 15. So as far as I can remember, I'd been bodybuilding my entire life.

For 15 years, I religiously followed a bodybuilding and nutrition regiment. I knew so much about the two, I honestly felt almost all trainers, bodybuilders and nutritionists were idiots. Even though it wasn't my profession, bodybuilding and nutrition was my passion.

But unfortunately, no matter how much effort and dedication I put in...it never really paid off. People that barely knew anything about bodybuilding, almost zilch about nutrition and were half assing their workouts, were making gains in less than a year what took me 15 years. And I'm not talking about your genetic freaks. I'm talking about your average Joe.

With clothes on, ppl couldn't even tell I worked out. What's more frustrating was when I told people about that, they said "you must be doing something wrong" "you gotta change your diet" "change your training" "you have to hit your muscles slower, faster"...etc. And all I could think was "Really dude? You really think in 15 years I haven't tried every single variable? You think the reason I haven't packed on slabs of muscle is because I didn't go slower on the weights or that I didn't eat an extra spoon of peanut butter?"

About 12 years into bodybuilding natty, I decided to start cycling. Unfortunately, I never done blood work beforehand.

I made nice gains, nothing spectacular, just satisfactory. But for the first time in my life, people were coming at me with "wow!" while checking out my physique. The compliments meant that results weren't bad at all.

Cycle ended. Ran PCT. Went back to my natty regiment.
Unfortunately, I lost most of the gains I'd made in about 6 months even though I tried all I could to maintain and add to the gains.

2 years after my first cycle, I started another one. 6 months after ending it, like the first time, I was left with nothing to brag about.

-Typical stats off-cycle:
Weigh: 214
Body fat: %16

-1st cycle:
Week 1 - 4: D bol 35mg ED
Week 1 - 12: Test E 500mg EW (250mg x 2)

-PCT (1st cycle):
HCG @ 1000 IU ED for 10 days, 4 days after last pin of Test E, then...

Clomid:
100/100/50/50
Nolvadex:
40/40/20/20

-2nd cycle:
Week 1-2: Anadrol @ 50mg ED
Week 3-4: Anadrol @ 100mg ED
Week 1-12: Deca @ 500mg EW
Week 1-15: Test C @ 600mg EW
Week 1-16: Eq @ 600mg EW

-PCT (2nd cycle):
HCG @ 1000 IU ED for 10 days, 4 days after last pin of Test E, then...

Nolvadex: 20/20/20/10/10
Clomid: 50/50/50/25/25

About a year after my 2nd cycle, I moved, started traveling a lot, hence I wasn't able to maintain my bodybuilding and nutrition regiment. I stopped going to the gym. And since I wasn't working out, I felt dieting and 6 healthy meals a day was useless. So for the first time in my life (well, sorta), I started eating junk food. Plan was to get back on track soon as I settled down.

Settling down didn't come till 3 months later. But by then, I'd already broken my habit. I was too lazy and too demotivated to get back to my healthy lifestyle.

4 years later, today, I'm yet to get back to working out and eating healthy. I've been leading a pretty sedentary lifestyle and my diet consists of a lot of fried food and white carbs. Needless to say, 15 years of gains went down the drain. I now stand at the above stats. Used to hover at around %15-18 body fat.

So now I'm looking into TRT and getting back on track with training and nutrition. I'm hoping TRT will enable me to see gains that I should have seen at the gym a long time ago. As well as fix all the other issues in "what got me to suspect low testosterone".

As you can see from the lab results, my testosterone is too low. Cause is something I'm yet to determine. I'm hoping you guys can chime in. Judging by the difficulty in gaining muscle, I really think I've always had below average testosterone levels, but then I can't be sure since I'd never done blood test until now.

Thank you for taking the time to read my post and for any point in the right direction!
 
Man this is a long one. I didn't have time to read the whole thing but your TT is obviously extremely low. You may be able to get the TSH down by adding HCG and pregnenolone to your protocol.

I would always try to fix thyroid with hard meds last, it is extremely tricky to dial them in and you want to try and get the thyroid moving without them if possible.

Physical activity will have a lot to do with this as well.
 
Agree with IMT; TRT brought my TSH back down from subclinical to in range with just diet and exercise. Just remember that it takes time for therapy to bring about truly noticeable results.

The one caveat being that an MRI of your pituitary might be a good idea given your upper range prolactin. SHBG makes sense given hypogonadism, as do the test/free test, but I find it odd to see a higher (in range) estradiol with a matching PRL. Worth looking into to rule out a potential pituitary tumor.

My .02c :)
 
Agree with IMT; TRT brought my TSH back down from subclinical to in range with just diet and exercise. Just remember that it takes time for therapy to bring about truly noticeable results.

The one caveat being that an MRI of your pituitary might be a good idea given your upper range prolactin. SHBG makes sense given hypogonadism, as do the test/free test, but I find it odd to see a higher (in range) estradiol with a matching PRL. Worth looking into to rule out a potential pituitary tumor.

My .02c :)

Thanks for your input halwit!

So low test causes a decrease in SHBG?
 
Thanks for your input halwit!

So low test causes a decrease in SHBG?

Indirectly, yes. Low testosterone can impact the thyroid, which will have a direct impact on SHBG. I believe insulin/glucose also has an impact, but it has been awhile since I delved into that aspect. :)
 
Indirectly, yes. Low testosterone can impact the thyroid, which will have a direct impact on SHBG. I believe insulin/glucose also has an impact, but it has been awhile since I delved into that aspect. :)

So what's your analysis of my situation? Where do you suggest I start with the treatment?
 
So what's your analysis of my situation? Where do you suggest I start with the treatment?

I would ask your physician if an MRI of your pituitary (BEFORE TRT is started) is feasible to rule out a tumor. If that's the case, and it's operable/treatable, there is a potential chance to recover your natural production.

If that is ruled out I would certainly go the TRT route with injections. There's a wonderful sticky at the top that covers many topics one should know before starting therapy as many doctors aren't quite up to speed on testosterone replacement therapy.
 
I would ask your physician if an MRI of your pituitary (BEFORE TRT is started) is feasible to rule out a tumor. If that's the case, and it's operable/treatable, there is a potential chance to recover your natural production.

If that is ruled out I would certainly go the TRT route with injections. There's a wonderful sticky at the top that covers many topics one should know before starting therapy as many doctors aren't quite up to speed on testosterone replacement therapy.

If I start TRT, what about the hypothyroidism?? Is the TRT going to fix that issue?
 
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