Gh Burst

[DIEZEL666]

Has anyone tried one of the GH bursts that Author Rea writes about? It consists of taking 2iu 4x Day for 3-4 days, then a four day break. It is supposed to mimic the natural GH release of growing teenagers. Any experience?

 

[StoneColdNTO]

Nope........first I've heard about it.

 

[einstein1905]

IMO, it's backwards logic.....mixing up cause and effect. While growing, we grow in spurts because of erratic GH release......NOT, we grow in spurts, so GH is released to accommodate.
Consistently elevated levels of GH (and therefore IGF-1) promote consistent growth.

 

[DIEZEL666]

What about negative feedback loops over time?

 

[ld50]

slow and steady wins the race.

there is a negative feedback loop w/ everything. you just cycle on and off, like anything else.

-ida

 

[Mudge]

IMO, it's backwards logic.....mixing up cause and effect.

Do we even have to get into his 500mg a day shots of enanthate for a couple weeks at a time theories?

Sorry but that guy is on the chronic.

 

[einstein1905]

What about negative feedback loops over time?

GH is regulated over very short periods. GH pulses occur about every 4 hrs, although GH itself has an inhibitory effect on its own release, it's IGF-1 that is the main negative feedback molecule. IGF-1 increases in response to GH, and it's really the levels of IGF-1 that will determine when the next GH pulse occurs. IGF-1 increases expression of somatostatin, but as IGF-1 levels decrease, expression of GHRH becomes dominatn over somatostatin, and the result is another GH pulse (release of GH from the anterior pituitary). Again, this occurs roughly every 4 hrs, with things like fasting, resistance training and sleep patterns altering it slightly

 

[Homer101]

GH is regulated over very short periods. GH pulses occur about every 4 hrs, although GH itself has an inhibitory effect on its own release, it's IGF-1 that is the main negative feedback molecule. IGF-1 increases in response to GH, and it's really the levels of IGF-1 that will determine when the next GH pulse occurs. IGF-1 increases expression of somatostatin, but as IGF-1 levels decrease, expression of GHRH becomes dominatn over somatostatin, and the result is another GH pulse (release of GH from the anterior pituitary). Again, this occurs roughly every 4 hrs, with things like fasting, resistance training and sleep patterns altering it slightly

good post