Increase skeletal muscle & collagen synthesis with certain AAS

TB500 did nothing for me. After reading this and being plagued with injuries I am ready to give this a chance.

I have been told by a few that even a low dosage of Test alone will help recovery of minor issues such as tendinitis. Is this true if used at <200mg a week? My question is what part of the compound in Deca / EQ relates to the collagen synthesis?

I would do low dose test with decent-high dose var IMO.
 
Increase skeletal muscle & collagen synthesis with certain AAS

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(originally posted by AnimalMass)

While injecting test increases protein synthesis by roughly 50 times, depending on dose and time, most bodybuilders forget that it will reduce collagen synthesis by more than 50% -- more like 80%, giving you the collagen synthesis rate of a senior citizen. Since collagen makes up tendons, bros are very prone to injury if they continue to lift very heavy, unless they cycle off T and let their collagen synthesis get back to normal. It's like having the skeletal muscle of a gorilla with the tendons of a very old man.

Winstrol increases collagen synthesis. It will give you bigger tendons. However, your body compensates for this by making them more brittle, weaker, and more prone to injury. I can't tell you how many bros work out anaerobically and become injured while on winstrol. Guys who lift in the 1-5 rep range while on winstrol, to baseball players who sprint all out from a stationary position -- winstrol should be the LAST drug they choose. Most of them like winstrol because they don't get the weight gain from it but it is very detrimental to bros who train for any sport anaerobically. Tendons tear easily on it.

Also, the drugs I mention increase collagen synthesis while also increasing collagen cross-linking integrity, making for a much stronger tendon.

Winstrol, on the other hand, will dramatically increase collagen syn, but ironically it decreases collagen cross-linking integrity, thus making a much weaker tendon.

You can plan a cycle of AAS which will increase collagen synthesis and skeletal muscle growth at the same time. The key is the drug(s) you choose.

Deca, Equipoise, Anavar, and Primobolan will ALL increase skeletal muscle while at the same time dramatically increase collagen syn and bone mass and density, leaving you with a substantially reduced chance of becoming injured than if you choose to use AAS like sus, cyp, or enth.

While testosterone will increase bone mass and density, even at supra-physiological levels, the result is weaker tendons due to inhibition of collagen syn.

To plan a cycle where the goal is to increase skeletal muscle mass/strength while at the same time increase joint/tendon/ligament strength, enough to keep up with the dramatic increase in skeletal muscle, you must choose drugs like Eq, Deca, Anavar, or Primo as the base of your cycle. Testosterone and its esters can be added to your cycle to keep levels within a 'normal' physiological range (ie, 100-200 mg/wk) but must not go above this. Since drugs like eq, deca, anavar and primo will reduce endogenous, natural levels of test, these levels may be maintained with exogenous test in the 100-200 mg/wk range. Test at this dose will not inhibit collagen syn, but paradoxically, will help increase it. It is when exogenous testosterone is used > 200 mg/wk that collagen syn is inhibited.

Deca @ 3 mg/kg a week(about 270 mg/wk for a 200 lb male) will increase procollagen III levels by 270% by week 2. Procollagen III is a primary indicator used to determine the rate of collagen syn. As you can see, deca is a very good drug at giving you everything you want -- an increase in collagen syn, an increase in skeletal muscle, and increases in bone mass and density. The one thing it does not give you is wood.

Primobolan, @ 5 mg/kg, will increase collagen synthesis by roughly 180% -- less than deca and equipoise but still substantial.

Equipoise @ 3 mg/kg will increase procollagen III by approximately 340% -- slightly better than deca.

Oxandrolone has over a hundred studies documenting its effectiveness at treating patients needing rapid increases in collagen syn to enhance healing.

These drugs have longer half-lives than most other AAS, so this should be considered when timing your post cycle Clomid use. Here they are:

Deca: 15 days Equipoise: 14 days Primobolan: 10.5 days

Anavar has a half-life of only 8 hours so it should not pose a problem.

GH is probably the most remarkable drug at increasing collagen synthesis. It increases collagen syn in a dose dependant manner -- the more you use, the more you will increase collagen syn. It has also demonstrated this ability in short and long term studies. From what I've read, hGH at 6 iu/day increased the collagen deposition rate by around 250% in damaged collagen structures. This result indicates that the increased biomechanical strength of wounds to collagen structures treated with biosynthetic human growth hormone was produced by an increased deposition of collagen in the collagen structures.

Eq, primo, anavar, and deca are all good -- they increase several biomakers of collagen syn -- ie, type III, II, I, procollagen markers. GH just seems to do so most dramatically.

Use of any of these drugs @ supra-physiological levels with a maintenance dose of test will increase collagen syn while at the same time increase skeletal muscle mass. Skeletal muscle mass gains will not be as dramatic as with large testosterone doses but you have to weigh the risk/reward basis for yourself. Also, these drugs do not satisfy the libido like testosterone, but that is not the point of this thread. It is only to demonstrate that you can increase skeletal muscle and collagen syn at the same time with certain AAS -- the decision is up to you.
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Maybe i missed it, but is there any empirical evidence, or references that prove EQ actually does what the writer of this article is claiming that it does? It's a great article... but if there is no proof, then it could be completely useless.
 
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Maybe i missed it, but is there any empirical evidence, or references that prove EQ actually does what the writer of this article is claiming that it does? It's a great article... but if there is no proof, then it could be completely useless.

A few months old, but I was researching anavar and collagen synthesis anyway and found this thread while doing so. Here is some researching showing anavar is amazing for collagen growth:

However, oxandrolone stimulated expression of type III procollagen mRNA 11-fold and type I procollagen mRNA doubled in fibroblasts maintained on collagen, relative to control fibroblasts maintained on collagen. A collagen substrate inhibits types I and III procollagen mRNA expression in fibroblasts. The anabolic steroid, oxandrolone, antagonizes such collagen substrate inhibition of procollagen mRNA expression, stimulating procollagen mRNA expression to levels of fibroblasts growing on plastic. These findings suggest that oxandrolone may directly enhance wound healing by increasing the expression of procollagen mRNA in fibroblasts associated with a collagen matrix analogous to the healing wound.
http://www.medscape.com/viewarticle/403338

I cannot see the entire article, but I think you get the gist of its findings from the executive summary at the start of the article.
 
hei, I'm 34 years old 94kg weight 186cm
have injury in bove shoulders left one had surgery I had splitted two shoulder capsule lips, I had laterjet surgery, after 6 years still trying to recover but sometimes because of pain I need to stop, also I had golf elbow disease so wondering to make a cycle to recover my joints I was thinking to make cycle but before maybe I will try TB 500 to see will it help , because when I will start cycle I do not want to drop after 1 month and begin PCT... So I think to make a cycle after of test propionate, EQ and anavar, but do not know dosage and how long do I need to take it also when I need to start HCG and what kind off PCT should I use, does anyone can make me schema how should I use it . I got some suggestion off PCT to use proviron, clomid, aroma and after One week finish with pregnyl...? is it good plan? I think I should kick in HCG somewhere. thanks
 
References

Increase skeletal muscle & collagen synthesis with certain AAS

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(originally posted by AnimalMass)

While injecting test increases protein synthesis by roughly 50 times, depending on dose and time... Etc

You got references for the claims made in this regarding collagen synthesis and the doses of mentioned AAS?
 
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