Decided to use letro this go round. I'm starting at .25mg e3d. I'm getting bloods done in like 8 days as the test will be fully in my system by them. I assume the letro will be fully kicked in by then so I have an accurate number for my e2 then I will be able to adjust my dose accordingly. Do you notice letro quickly or does it take a couple days to fully be in the system?