Letrozole - When to Start?
- Thread starter ZNIG
- Start date
Start it at the same time as your cycle, if not earlier. Here is some information on letro:
Interestingly, it takes approximately 60 days to get a steady blood plasma level of letrozole once administration of the drug begins*. This may necessitate that a user begin using the compound prior to beginning their cycle if they wish for the effects to be at full strength once their cycle begins. This may also hinder the ability of the compound to respond quickly if a user begins administration of the drug to counteract some side effects that have appeared quickly.
*Buzdar AU. Pharmacology and pharmacokinetics of the newer generation aromatase inhibitors. Clin Cancer Res. 2003 Jan;9(1 Pt 2):468S-72S
Interestingly, it takes approximately 60 days to get a steady blood plasma level of letrozole once administration of the drug begins*. This may necessitate that a user begin using the compound prior to beginning their cycle if they wish for the effects to be at full strength once their cycle begins. This may also hinder the ability of the compound to respond quickly if a user begins administration of the drug to counteract some side effects that have appeared quickly.
*Buzdar AU. Pharmacology and pharmacokinetics of the newer generation aromatase inhibitors. Clin Cancer Res. 2003 Jan;9(1 Pt 2):468S-72S
simpllyhuge
New member
so aboot how should this info affect my dose? maybe im thinking i need a higher dose than i do because it hasnt fully kicked in yet?
Well, depends if you are using it for prevention purposes or to treat an existing condition. If it is just for prevention, I would stick with a moderate dosage. No need to set yourself up for potentially negative side effects. However if you are battling gyno, then yes you may want to err on the side of a larger dosage to try and get it under control quickly.
simpllyhuge
New member
i asked this before but i want your personal opinion. to tottaly keep bloat off on about 750- 1000 of test how much arimidex do u suggest. Im not concernced about gyno just want to keep the bloat off because mentally it allows me to judge my diet better and feel better about bulking. im using liquid so every day is easy for me.
Also i plan on adding Winstrol (winny) in later on so should i drop the letro dose then?
Also i plan on adding Winstrol (winny) in later on so should i drop the letro dose then?
simpllyhuge
New member
sorry i ment letro, im just so used to saying adex. the reason i asked about the Winstrol (winny) was because of the Winstrol (winny) helping with the bloat which you already answered, but i was also curious if it was okay since letro i heard affects lipids and so does Winstrol (winny). thanks
For letro, guys have said that they saw results using anywhere from 25mgs to as much as 2.5mgs per day. Of course you want to use as little as is necessary, so start low and increase as needed. It is rather harsh for some guys so watch for side effects (i.e. possible sexual dysfunction).
As for cholesterol, yes both letro and winstrol negatively impact it. However the severity that they do varies from user to user. As long as you aren't using either compound for an extended period of time there should be no significant risk for harm.
As for cholesterol, yes both letro and winstrol negatively impact it. However the severity that they do varies from user to user. As long as you aren't using either compound for an extended period of time there should be no significant risk for harm.
simpllyhuge
New member
maybe ill try .75 a day or 1.0. im higher than that right now but that was because i wanted it to work faster. i never used to like liquids cause they were messy and i didnt trust them. but since i bought researchology i am confident using them for things that are longer acting with the pump because u dont have to be that accurate because if people are using something like letro every third day and im using it ed than i am comfortable using the convienent pump because it averages out.
