low HDL
- Thread starter nerdalert
- Start date
CHIP WADOWSKI
New member
Hey "nerd-squirts" lol... sorry about the delayed response. Was completely buried AND my perfect little WHORE told me that if I didn't show her why I Am MR. MAXIMUS, and blow her pussy up for a good couple hours, that she was going to refrain from giving me her tight little Ms. MAXIMUS asshole for ONE WEEK!! FUCK THAT!
So, I preserved my spot at the top of the food chain after dropping 270lbs of POLISH THUNDER into that tight little Garden Of Eden and let her know who's KING! She enjoyed a good nights sleep with an ICE PACK on her pussy after I grabbed it off the wall in the opposite corner of the room and gave it back to her! I did find two articles that you will hopefully find helpful. You guys all know I'm not big on all the copy and paste stuff, but I found these to be relatively basic and comprehensive "reads" that seemed to address your questions and many more. Hope they help you. Thx!
http://www.americanheart.org/presenter.jhtml?identifier=183
Low Testosterone Symptoms
Dreaded Pirate Roberts
Administrator
Niacin is known to increase HDL better than any medication. As shown in the following abstract, athletes who use anabolic steroids have very low HDL (high density lipoprotein) blood levels. HDL is the ***8220;cleaning agent***8221; that removes what the dirty guy (LDL) deposits in the blood vessels. Low HDL can have a dramatic impact of cardovascular health.
Lipids in Power Athletes Self-Administering Testosterone and Anabolic Steroids
M. Alén 1,2, P. Rahkila 2, J. Marniemi 3
1 Department of Health Sciences, University of Jyväskylä, Jyväskylä, Finland
2 Research Unit for Sport and Physical Fitness, Jyväskylä, Finland
3 The Rehabilitation Research Center of the Social Insurance Institution, Turku, Finland
Abstract
The purpose of the present investigation was to study the effects of testosterone and anabolic steroids on serum lipids in power athletes. Altogether 11 national top-level adult athletes completed the study. Five of them volunteered for the study group and the rest for controls. The follow-up consisted of 9 months of a strength training period. During the first 6 months, the subjects in the study group self-administered androgenic steroids on an average of 57+24.9 mg/day.
The most interesting observation was the extremely low high-density lipoprotein (HDL) and HDL2cholesterol concentrations of the androgen users. After 8 weeks of training, the study group had significantly (P < 0.05) lower HDL cholesterol concentrations than the control group (0.53±0.11 and 1.14±0.19 mmol/l, respectively). This difference remained significant from 8 to 32 weeks of training. No systematic changes were observed in the control group. The HDL2 cholesterol concentration decreased by about 80% (P < 0.01) and HDL3 cholesterol by about 55% (P < 0.01) from the onset values in the study group.
A substantial decrease in HDL cholesterol to total cholesterol and in HDL2cholesterol to HDL3cholesterol ratios were also noticed under the influence of exogenous androgens.
The results of this study suggest that the sustained use of testosterone and anabolic steroids have a marked unfavorable effect on the pattern of HDL cholesterol in the serum of male power athletes.
*******************************************************************
Niacin is known to increase HDL better than any medication.
Regular over-the-counter niacin or nicotic acid, usually taken at a dose of 300-500 mg 3 x day, is a B3 vitamin shown to effectively increase good cholesterol, HDL, with some modest decrease in LDL. Many people take it along with a statin for best results. There have been concerns about liver toxicity and insulin resistance with niacin use, but several studies have found no such problem. But it has a flushing effect can make you feel like your skin is burning and itching a lot, which usually goes away after 20 minutes.
Some people say that taking a baby aspirin (81 mg) 30 min to an hour before taking Niacin really helps to minimize the flushing. Some people report less flushing when taking Niacin with a higher fat meal. Some take it before going to bed to sleep through the flushing effect. Start with lower dose of 250 mg a day and build up slowly up to 1000 mg per day. Get your doctor to check your fasting lipids (and liver enzymes) after a month of being on 1000 mg a day to see if this dose needs to be increased to 1500- 2000 mg a day.
Niaspan (KOS Pharmaceuticals) is a prescription form of extended release niacin. A placebo-controlled, double-blind trial in 122 HIV-negative patients with primary dyslipidemia compared Niaspan 1000 and 2000 mg/ day with placebo. Niaspan reduced LDL cholesterol significantly compared with placebo. In addition, triglyceride levels were decreased 21% with the 1000-mg/day dosage and 28% with the 2000-mg/day dosage. Approximately 85% of the patients taking Niaspan had some flushing, but this reaction did not differ in frequency, intensity, or duration between the two dosages. In two patients the aspartate transaminase level (liver enzyme) was more than twice the normal level, and in one the alanine transaminase level was elevated to more than three times normal.
Good sources of niacin include yeast, meat, poultry, red fishes (e.g., tuna, salmon), cereals (especially fortified cereals), legumes, and seeds. Milk, green leafy vegetables, coffee, and tea also provide some niacin.
Inositol hexanicotinate, a chemical cousin of nicotinic acid, is marketed as beneficially raising HDL cholesterol the same as nicotinic acid but without the skin flushing side effect. But critics argue that studies done to support the cholesterol-regulating properties of inositol hexanicotinate are out of date because they were conducted in the early 1960s. They also argue they were not conclusive.
There has been some debate as to whether or not flush-free niacin lowers cholesterol levels. In fact, there have not been enough studies to support or deny this. One study has indicated that up to 2,400 mg of flush-free niacin each day (in divided doses) is needed to lower cholesterol levels, whereas other studies have indicated that flush-free niacin is ineffective in lowering cholesterol.
One interesting study examining different forms of niacin measured the amounts of free nicotinic acid (the main compound in regular niacin) found in the blood after the no flush product was ingested. The study found that after 1.6 grams of inositol hexaniacinate was taken, only 0.6 micromoles/L of nicotinic acid was detected in the blood.
So, if you are using anabolics and are not monitoring your blood lipids, do so. If your HDL is below 40 mg/dl, consider starting over the counter Niacin or getting a prescription of Niaspan from your doctor.
More on HDL : High-density lipoprotein - Wikipedia, the free encyclopedia
Nelson Vergel
Author of ***8220;Testosterone: A Man***8217;s Guide***8221;
Related Posts
Lipids in Power Athletes Self-Administering Testosterone and Anabolic Steroids
M. Alén 1,2, P. Rahkila 2, J. Marniemi 3
1 Department of Health Sciences, University of Jyväskylä, Jyväskylä, Finland
2 Research Unit for Sport and Physical Fitness, Jyväskylä, Finland
3 The Rehabilitation Research Center of the Social Insurance Institution, Turku, Finland
Abstract
The purpose of the present investigation was to study the effects of testosterone and anabolic steroids on serum lipids in power athletes. Altogether 11 national top-level adult athletes completed the study. Five of them volunteered for the study group and the rest for controls. The follow-up consisted of 9 months of a strength training period. During the first 6 months, the subjects in the study group self-administered androgenic steroids on an average of 57+24.9 mg/day.
The most interesting observation was the extremely low high-density lipoprotein (HDL) and HDL2cholesterol concentrations of the androgen users. After 8 weeks of training, the study group had significantly (P < 0.05) lower HDL cholesterol concentrations than the control group (0.53±0.11 and 1.14±0.19 mmol/l, respectively). This difference remained significant from 8 to 32 weeks of training. No systematic changes were observed in the control group. The HDL2 cholesterol concentration decreased by about 80% (P < 0.01) and HDL3 cholesterol by about 55% (P < 0.01) from the onset values in the study group.
A substantial decrease in HDL cholesterol to total cholesterol and in HDL2cholesterol to HDL3cholesterol ratios were also noticed under the influence of exogenous androgens.
The results of this study suggest that the sustained use of testosterone and anabolic steroids have a marked unfavorable effect on the pattern of HDL cholesterol in the serum of male power athletes.
*******************************************************************
Niacin is known to increase HDL better than any medication.
Regular over-the-counter niacin or nicotic acid, usually taken at a dose of 300-500 mg 3 x day, is a B3 vitamin shown to effectively increase good cholesterol, HDL, with some modest decrease in LDL. Many people take it along with a statin for best results. There have been concerns about liver toxicity and insulin resistance with niacin use, but several studies have found no such problem. But it has a flushing effect can make you feel like your skin is burning and itching a lot, which usually goes away after 20 minutes.
Some people say that taking a baby aspirin (81 mg) 30 min to an hour before taking Niacin really helps to minimize the flushing. Some people report less flushing when taking Niacin with a higher fat meal. Some take it before going to bed to sleep through the flushing effect. Start with lower dose of 250 mg a day and build up slowly up to 1000 mg per day. Get your doctor to check your fasting lipids (and liver enzymes) after a month of being on 1000 mg a day to see if this dose needs to be increased to 1500- 2000 mg a day.
Niaspan (KOS Pharmaceuticals) is a prescription form of extended release niacin. A placebo-controlled, double-blind trial in 122 HIV-negative patients with primary dyslipidemia compared Niaspan 1000 and 2000 mg/ day with placebo. Niaspan reduced LDL cholesterol significantly compared with placebo. In addition, triglyceride levels were decreased 21% with the 1000-mg/day dosage and 28% with the 2000-mg/day dosage. Approximately 85% of the patients taking Niaspan had some flushing, but this reaction did not differ in frequency, intensity, or duration between the two dosages. In two patients the aspartate transaminase level (liver enzyme) was more than twice the normal level, and in one the alanine transaminase level was elevated to more than three times normal.
Good sources of niacin include yeast, meat, poultry, red fishes (e.g., tuna, salmon), cereals (especially fortified cereals), legumes, and seeds. Milk, green leafy vegetables, coffee, and tea also provide some niacin.
Inositol hexanicotinate, a chemical cousin of nicotinic acid, is marketed as beneficially raising HDL cholesterol the same as nicotinic acid but without the skin flushing side effect. But critics argue that studies done to support the cholesterol-regulating properties of inositol hexanicotinate are out of date because they were conducted in the early 1960s. They also argue they were not conclusive.
There has been some debate as to whether or not flush-free niacin lowers cholesterol levels. In fact, there have not been enough studies to support or deny this. One study has indicated that up to 2,400 mg of flush-free niacin each day (in divided doses) is needed to lower cholesterol levels, whereas other studies have indicated that flush-free niacin is ineffective in lowering cholesterol.
One interesting study examining different forms of niacin measured the amounts of free nicotinic acid (the main compound in regular niacin) found in the blood after the no flush product was ingested. The study found that after 1.6 grams of inositol hexaniacinate was taken, only 0.6 micromoles/L of nicotinic acid was detected in the blood.
So, if you are using anabolics and are not monitoring your blood lipids, do so. If your HDL is below 40 mg/dl, consider starting over the counter Niacin or getting a prescription of Niaspan from your doctor.
More on HDL : High-density lipoprotein - Wikipedia, the free encyclopedia
Nelson Vergel
Author of ***8220;Testosterone: A Man***8217;s Guide***8221;
Related Posts
JOWS6
I am banned!
I'm getting a lot of contradicting findings that makes it hard to piece together how much testosterone replacement therapy (TRT) impacts HDL levels. Here's some of the findings I came across:
Assessment of possible effects for testosterone replacement therapy in men with symptomatic late-onset hypogonadism
"Total and psychological symptoms scores were measured by the AMS scale and the ADAM questionnaire score, demonstrating that the sum of positive responses to the questions were significantly improved after testosterone replacement therapy (TRT) ( P < 0.05). TC, HDL, and LDL cholesterol, TG, AST, ALT, ***947;-GTP, RBC, Hb, Ht, and PSA were not significantly different between before and after TRT. Although testosterone replacement therapy (TRT) for men with LOH may cause favorable changes in psychological conditions, it may not have effects on lipid metabolism, liver function, RBC, and PSA level."
Effects of testosterone replacement on HDL subfractions and apolipoprotein A-I containing lipoproteins
"In conclusion, testosterone replacement in the form of 4-weekly intramuscular injection of testosterone enanthate,although far from ideal as it could not mimic the natural profile
of endogenous testosterone secretion and resulted in a slightly subphysiological trough testosterone level, was not associated with unfavourable changes in lipid profiles. There were no associated changes in triglyceride, LDL-C and apo(a) and the decrease in HDL-C was transient. The reduction was mainly in HDL-C3 and in LpA-I:A-II particles and not in the more antiatherogenic HDL2 and LpA-I particles. Plasma cholesteryl ester
transfer protein activity in hypogonadal men was similar to controls and was not affected by testosterone replacement. The changes in HDL subclasses was mainly mediated through the effect of testosterone on hepatic lipase activity."
Effects of testosterone on body composition, bone metabolism and serum lipid profile in middle-aged men: a meta-analysis.
"Testosterone also reduced total cholesterol by 0·23 mmol/l (CI: ***8722;0·37 to ***8722;0·10), especially in men with lower baseline T concentrations, with no change in low density lipoprotein (LDL)-cholesterol. A significant reduction of high density lipoprotein (HDL)-cholesterol was found only in studies with higher mean T-values at baseline (***8722;0·085 mmol/l, CI: ***8722;0·017 to ***8722;0·003). Sensitivity and meta-regression analysis revealed that the dose/type of T used, in particular the possibility of aromatization, explained the heterogeneity in findings observed on bone density and HDL-cholesterol among studies."
An Exploratory Study of the Effects of 12 Month Administration of the Novel Long-Acting Testosterone Undecanoate on Measures of Sexual Function and the Metabolic Syndrome
"These parameters were not assessed in this study but the impact of testosterone administration on fat mass and lean body mass has been shown in other studies [Page et al. 2005]. Waist circumference, blood pressure, plasma cholesterol, LDL and triglycerides declined and plasma HDL increased. With the exception of triglycerides these changes were correlated and ascribed to the normalization of plasma T since
diet and physical exercise were not altered."
There seems to be a negative impact on eugonadal men but testosterone administration in hypogonadal men suggests a minimal or positive effect on HDL levels. Is anyone else interpreting these findings the same way?
Assessment of possible effects for testosterone replacement therapy in men with symptomatic late-onset hypogonadism
"Total and psychological symptoms scores were measured by the AMS scale and the ADAM questionnaire score, demonstrating that the sum of positive responses to the questions were significantly improved after testosterone replacement therapy (TRT) ( P < 0.05). TC, HDL, and LDL cholesterol, TG, AST, ALT, ***947;-GTP, RBC, Hb, Ht, and PSA were not significantly different between before and after TRT. Although testosterone replacement therapy (TRT) for men with LOH may cause favorable changes in psychological conditions, it may not have effects on lipid metabolism, liver function, RBC, and PSA level."
Effects of testosterone replacement on HDL subfractions and apolipoprotein A-I containing lipoproteins
"In conclusion, testosterone replacement in the form of 4-weekly intramuscular injection of testosterone enanthate,although far from ideal as it could not mimic the natural profile
of endogenous testosterone secretion and resulted in a slightly subphysiological trough testosterone level, was not associated with unfavourable changes in lipid profiles. There were no associated changes in triglyceride, LDL-C and apo(a) and the decrease in HDL-C was transient. The reduction was mainly in HDL-C3 and in LpA-I:A-II particles and not in the more antiatherogenic HDL2 and LpA-I particles. Plasma cholesteryl ester
transfer protein activity in hypogonadal men was similar to controls and was not affected by testosterone replacement. The changes in HDL subclasses was mainly mediated through the effect of testosterone on hepatic lipase activity."
Effects of testosterone on body composition, bone metabolism and serum lipid profile in middle-aged men: a meta-analysis.
"Testosterone also reduced total cholesterol by 0·23 mmol/l (CI: ***8722;0·37 to ***8722;0·10), especially in men with lower baseline T concentrations, with no change in low density lipoprotein (LDL)-cholesterol. A significant reduction of high density lipoprotein (HDL)-cholesterol was found only in studies with higher mean T-values at baseline (***8722;0·085 mmol/l, CI: ***8722;0·017 to ***8722;0·003). Sensitivity and meta-regression analysis revealed that the dose/type of T used, in particular the possibility of aromatization, explained the heterogeneity in findings observed on bone density and HDL-cholesterol among studies."
An Exploratory Study of the Effects of 12 Month Administration of the Novel Long-Acting Testosterone Undecanoate on Measures of Sexual Function and the Metabolic Syndrome
"These parameters were not assessed in this study but the impact of testosterone administration on fat mass and lean body mass has been shown in other studies [Page et al. 2005]. Waist circumference, blood pressure, plasma cholesterol, LDL and triglycerides declined and plasma HDL increased. With the exception of triglycerides these changes were correlated and ascribed to the normalization of plasma T since
diet and physical exercise were not altered."
There seems to be a negative impact on eugonadal men but testosterone administration in hypogonadal men suggests a minimal or positive effect on HDL levels. Is anyone else interpreting these findings the same way?
The contradictory implications arises from the fact that very few of these studies follow the same experimental protocols for controlling the exogenous variables. Some stratify on age, some on body composition, some on other factors. Most have different treatments and almost none significantly implement controls for correlated factors.
A good example is this study, Testosterone dose-response relationships in healthy young men -- Bhasin et al. 281 (6): E1172 -- AJP - Endocrinology and Metabolism.
It is widely cited but even in its experimental design, there are very few controls.
Without consistent replication of design, there is very little way to compare across studies, the findings reported by each.
Regards.
nerdalert
New member
When I did use the Niaspan it did have a positive effect on my hdl, but it still hadn't raised it to a level that I was comfortable with. At it's low it was only 17 and I had gotten it up to 30. I am still waiting for the results to come back from my dr to see what it is now. It has been a year since I took it.
MoparMuscle
Amateur Bodybuilder
My LDL was 105 and HDL 17 last test. Don't smoke, drink or eat ANYTHING unhealthy (organic nut).
I'm going to try increasing my fish / fish pill intake as well as get a Niacin supp.
I'm going to try increasing my fish / fish pill intake as well as get a Niacin supp.
Kristofer68ss
Squats and Deads S&M
Yep
Slo-Niacin works for sure.
Krill Oils as well.
I use Krill-TS or Krillipid by RPN
Sports nutrition :: Krill-TS - Ruthless Supplements
MoparMuscle
Amateur Bodybuilder
I guess cooking with coocinut oil is good also so I might try that to.
Kristofer68ss
Squats and Deads S&M
EVOO as well.
MoparMuscle
Amateur Bodybuilder
EVOO is great raw or warm but it has a really low heat point / smoke point and if you hot cook with it converts to a more harmful oil (I guess all the "good stuff" burns off above 200f), cocoanut oil has a high heat point and is safe to "hot cook" with foods.
Last edited:
Teutonic
New member
This is good stuff.
My blood work is ussually flawless with the exception of my lipids.
My lipid s were always off the mark..on gear or off.
My GP, who no longer does my testosterone replacement therapy (TRT) but does monitor my health as he know s I break out of doses at times, has recommended the above from the onset of his monitoring my blood level s.
I ll print this and share as he admittedly has limited knowledge of the poential long term effect s of someone who does TRT..and then 2-3 times a year, break s out for 6-10 weeks with double or triple the prescribed dose.
Thank s gents.
T
My blood work is ussually flawless with the exception of my lipids.
My lipid s were always off the mark..on gear or off.
My GP, who no longer does my testosterone replacement therapy (TRT) but does monitor my health as he know s I break out of doses at times, has recommended the above from the onset of his monitoring my blood level s.
I ll print this and share as he admittedly has limited knowledge of the poential long term effect s of someone who does TRT..and then 2-3 times a year, break s out for 6-10 weeks with double or triple the prescribed dose.
Thank s gents.
T
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